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Genomic Perl, Rex A. Dwyer

Genomic Perl

Автор: Rex A. Dwyer
Название:  Genomic Perl   (Геномы)
Издательство: Cambridge Academ
Молекулярная биология
Языки программирования

ISBN: 052180177X
ISBN-13(EAN): 9780521801775
ISBN: 0-521-80177-X
ISBN-13(EAN): 978-0-521-80177-5
Обложка/Формат: Hardcover
Страницы: 352
Вес: 0.816 кг.
Дата издания: 20.02.2003
Язык: ENG
Ссылка на Издательство: Link
Поставляется из: Англии
Описание: This introduction to computational molecular biology will help programmers and biologists learn the skills needed to start work in this important, expanding field. The author explains many of the basic computational problems and gives concise, working programs to solve them in the Perl programming language. With minimal prerequisites, the author explains the biological background for each problem, develops a model for the solution, then introduces the Perl concepts needed to implement the solution. The book covers pairwise and multiple sequence alignment, fast database searches for homologous sequences, protein motif identification, genome rearrangement, physical mapping, phylogeny reconstruction, satellite identification, sequence assembly, gene finding, and RNA secondary structure. The concrete examples and step-by-step approach make it easy to grasp the computational and statistical methods, including dynamic programming, branch-and-bound optimization, greedy methods, maximum likelihood methods, substitution matrices, BLAST searching, and Karlin-Altschul statistics. Perl code is provided on the accompanying CD.
Дополнительное описание: Subject: Computer science / Computational Biology and Bioinformatics
Readership: computational biology, molecular biology, bioinformatics, genetics
Level: undergraduate students, graduate students, academic researchers, professionals
Format: 253 x 177 mm 352pp 100 exercises
Chapter Titles: 1. The central dogma; 2. RNA secondary structure; 3. Comparing DNA sequences; 4. Statistical models; 5. Substitution matrices for amino acids; 6. Sequence databases; 7. Local alignment and the BLAST heuristic; 8. Statistics of BLAST database searches; 9. Multiple sequence alignment I; 10. Multiple sequence alignment II; 11. Phylogeny reconstruction; 12. Protein motifs and PROSITE; 13. Fragment assembly; 14. Coding sequence prediction with dicodon frequencies; 15. Satellite identification; 16. Restriction mapping; 17. Hybridization mapping; 18. Genome rearrangement: gates and hurdles; 19. Now what?; Appendix A: drawing RNA cloverleaves; Appendix B: space-saving strategies for alignment; Appendix C. a data structure for disjoint sets; Appendix D. a data structure for set operations.

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Molecular Biology and Genomics,

Автор: Cornel Mulhardt
Название: Molecular Biology and Genomics,
ISBN: 0120885468 ISBN-13(EAN): 9780120885466
Издательство: Elsevier Science
Цена: 3538 р.
Наличие на складе: Есть (1 шт.)
Описание: Exploring the methodological variety of molecular biology and genomics, this book addresses the assets and drawbacks as well as critical points. It provides summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods. It also shows how to avoid experimental dead ends.

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Automation: Genomic and Functional Analyses,28

Автор: Alister G. Craig
Название: Automation: Genomic and Functional Analyses,28
ISBN: 0125215274 ISBN-13(EAN): 9780125215275
Издательство: Elsevier Science
Цена: 12705 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

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Genomic Imprinting / Methods and Protocols

Автор: Ward Andrew
Название: Genomic Imprinting / Methods and Protocols
ISBN: 089603741X ISBN-13(EAN): 9780896037410
Издательство: Springer
Цена: 6156 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: Andrew Ward and a team of experienced researchers have brought together a collection of optimized classic and vanguard techniques for the identification and analysis of imprinted genes. Protocols are included for identifying and cloning imprinted genes, for analyzing imprinted gene expression, for the study of DNA methylation and methylation-sensitive DNA-binding proteins, and for examining chromatin structure. There are also methods for the manipulation of mouse embryos to produce monoparental embryos and embryonic stem cells, and for the generation of transgenic mice with BAC, PAC,and YAC constructs. Each technique is described in step-by-step detail to ensure successful results.

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Genomic Imprinting: Frontiers in Molecular Biology

Название: Genomic Imprinting: Frontiers in Molecular Biology
ISBN: 0199636257 ISBN-13(EAN): 9780199636259
Издательство: Oxford Academ
Цена: 7450 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: This book is intended for post-graduate and post-doctoral researchers and academic staff. It includes coverage of the role of DNA methylation in mammalian development; development regulation of imprinting by DNA methylation; and consequences of genomic imprinting for foetal development.

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Automation: Genomic and Functional Analyses,28

Автор: Alister G. Craig
Название: Automation: Genomic and Functional Analyses,28
ISBN: 0121948609 ISBN-13(EAN): 9780121948603
Издательство: Elsevier Science
Цена: 12705 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: Offers an explanation of the experimental techniques. This book discusses the clone library construction, genome analysis, sequencing, computation data evaluation and functional analysis. It describes automated procedures used in microbiology and molecular biology and includes developments in robotics and vision systems.

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Plant Genomics Databases

Автор: Aalt-Jan van Dijk
Название: Plant Genomics Databases
ISBN: 1493966561 ISBN-13(EAN): 9781493966561
Издательство: Springer
Цена: 8469 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: This volume introduces databases containing the results from the recent revolution in sequencing technologies. Chapters in Plant Genomics Databases: Methods and Protocols describe database content, as well as typical use-cases. Some chapters explore databases that primarily present genome sequences focusing on one or a few related species, while others include additional datatypes and/or data from various plant species. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and comprehensive, Plant Genomics Databases: Methods and Protocols is a valuable resource for providing clear guidance in accessing an important collection of plant databases that can be used to add biological value to genomic data.

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Автор: Primrose B Sandy, Khan Michael, Twyman Richard, Di
Название: Genomics
ISBN: 1405108193 ISBN-13(EAN): 9781405108195
Издательство: Wiley
Цена: 6468 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: Shows how the science of genomics is adding impetus to the advances in human health provided by biotechnology. This book introduces the role of biotechnology and genomics in medicine and sets out some of the technological advances that have been the basis of medical breakthroughs.

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Guide to Yeast Genetics: Functional Genomics, Proteomics and Othe

Автор: Jonathan Weissman
Название: Guide to Yeast Genetics: Functional Genomics, Proteomics and Othe
ISBN: 0123751713 ISBN-13(EAN): 9780123751713
Издательство: Elsevier Science
Цена: 6079 р.
Наличие на складе: Поставка под заказ.

Описание: Part of the "Methods in Enzymology" series, this title is specifically designed to meet the needs of graduate students, postdoctoral students, and researchers by providing various methods necessary to study genes in yeast. It also includes procedures that enable newcomers to set up a yeast laboratory and to master basic manipulations.

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Bioinformatics and the Cell / Modern Computational Approaches in Genomics, Proteomics and Transcriptomics

Автор: Xia Xuhua
Название: Bioinformatics and the Cell / Modern Computational Approaches in Genomics, Proteomics and Transcriptomics
ISBN: 0387713360 ISBN-13(EAN): 9780387713366
Издательство: Springer
Цена: 14392 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: The many books that have been written on bioinformatics tend to fall on two extremes: books that feature computational details with a great deal of mathematics, for computational scientists and mathematicians, or books that treat bioinformatics mostly as a giant black box, for biologists. Previous books written on bioinformatics often have limited contribution to creating interdisciplinary scientists needed in modern biological and biomedical sciences.This book aims to render both mathematical equations and biology to numbers, to help truly interdisciplinary scientists. Although the book covers bioinformatics methods at a level more advanced than most other bioinformatics books, the extensive numerical illustration of these methods should make it accessible to most senior undergraduate students and graduate students majoring in science and software engineering. Nearly all algorithms in the book are implemented in a free and user-friendly computer program (DAMBE).

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Genomics and Personalized Medicine

Автор: Snyder, Michael
Название: Genomics and Personalized Medicine
ISBN: 0190234776 ISBN-13(EAN): 9780190234775
Издательство: Oxford Academ
Цена: 4206 р.
Наличие на складе: Поставка под заказ.

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Structural Genomics, Part A,75

Автор: Andrzej Joachimiak
Название: Structural Genomics, Part A,75
ISBN: 0123744369 ISBN-13(EAN): 9780123744364
Издательство: Elsevier Science
Цена: 11011 р.
Наличие на складе: Поставка под заказ.

Описание: Structural genomics is the systematic determination of 3-dimensional structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.<br><br>While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large scale cloning, expression and purification. One main advantage of this approach is economy of scale. <br><br>Key Features<br>*Examines the three dimensional structure of all proteins of a given organism, by experimental methods such as X-ray crystallography and NMR spectroscopy <br><br>* Looks at structural genomics as a foundation of drug discovery as discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission<br><br>

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Foundations of Comparative Genomics,

Автор: Arcady R. Mushegian
Название: Foundations of Comparative Genomics,
ISBN: 0120887940 ISBN-13(EAN): 9780120887941
Издательство: Elsevier Science
Цена: 6079 р.
Наличие на складе: Поставка под заказ.

Описание: This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. "Foundations of Comparative Genomics" presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions.This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics.

It presents an historic overview of genome biology and its achievements. It includes topics not covered in other books such as minimal and ancestral genomes. It discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level.

It critically reviews horizontal gene transfer and other contentious issues. It covers comparative virology as a somewhat overlooked foundation of modern genome science.

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