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ABC Proteins, Holland

ABC Proteins

Автор: Holland
Название:  ABC Proteins   (Белки АВС)
Издательство: Elsevier Science
Классификация:
Энциклопедии и справочные материалы
Прикладная физика и специальные разделы
Биохимия

ISBN: 0123525519
ISBN-13(EAN): 9780123525512
ISBN: 0-12-352551-9
ISBN-13(EAN): 978-0-12-352551-2
Обложка/Формат: Hardcover
Страницы: 672
Вес: 2.01 кг.
Дата издания: January 7, 2003
Ссылка на Издательство: Link
Поставляется из: Англии
Описание: ABC proteins (ATP-Binding Cassette proteins) transport a variety of molecules across membranes. They comprise one of the largest protein families known - 56 members have been identified in humans alone. Different ABC proteins transport a remarkably varied range of vital molecules across membranes, from small molecules such as chloride ions through to large molecules such as cholesterol, anti-cancer drugs and bacterial toxins. Many mammalian ABC are of considerable medical importance and are implicated in genetic diseases such as heart disease, cystic fibrosis, Stargardts retinal dystrophy and adrenoleukodystrophy. Others are involved in the immune system, lung function, the arterial system, digestive system, kidney and liver function, apoptosis, retinal function, clinical multiple drug resistance, tumour cell growth and in infectious agents. The same family of proteins is also found in bacteria, fungi, insects, plants and mammals. In bacteria, ABC transporters are not only required for nutrient uptake, but are implicated in toxin and protease secretion, as well as multiple antibiotic resistance. The family is one of the fastest growing protein groups, and research - especially given the medical importance of these proteins - is increasing at an exponential rate. For instance, the number of NIH grants concerning ABC Proteins has risen 11-fold in the last 10 years. The pace is accelerating, and is expected to continue. This title forms an in depth analysis of all we know about ABC Proteins to date.
Дополнительное описание: Кол-во стр.: 672
Формат: 270 x 200
Дата издания: 2002
Страна: UK
Круг читателей: academic, specialist
Иллюстрации: Colour illustrations
Вес: 2010



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How proteins work

Автор: Williamson, Mike
Название: How proteins work
ISBN: 0815344465 ISBN-13(EAN): 9780815344469
Издательство: Taylor&Francis
Цена: 4488 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
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Cellular Lipid Binding Proteins

Автор: Glatz Jan F.C.
Название: Cellular Lipid Binding Proteins
ISBN: 1402072201 ISBN-13(EAN): 9781402072208
Издательство: Springer
Цена: 11931 р.
Наличие на складе: Нет в наличии.
Описание: It is well established that cellular lipid binding proteins serve central roles in cellular lipid uptake and metabolism. Evidence has been presented that various metabolic diseases, such as hyperlipidemia, atherosclerosis, insulin resistance, and diabetes, are characterized by malfunctioning or deficiencies in cellular lipid binding proteins. For better understanding of the action of lipids as signaling compounds and the role of lipids in intermediary metabolism, it is essential to have detailed knowledge of the interactions between lipids and their cognant binding proteins. In view of this growing interest in lipid-protein interaction, the 4th International Conference on Lipid Binding Proteins was held in Maastricht, The Netherlands, in June 2001. The proceedings of the previous three meetings have been published in Molecular and Cellular Biochemistry. The present focused issue of Molecular and Cellular Biochemistry comprises selected papers based on the lectures and posters presented during the 4th conference, and provides insight into the significance of these proteins for the functioning of the cell.
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PAS Proteins: Regulators and Sensors of Development and Physiology

Автор: Crews Stephen T.
Название: PAS Proteins: Regulators and Sensors of Development and Physiology
ISBN: 1402075863 ISBN-13(EAN): 9781402075865
Издательство: Springer
Цена: 7157 р.
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Описание: The subject of this volume is a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.
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Fluorescence Spectroscopy in Biology / Advanced Methods and their Applications to Membranes, Proteins, DNA, and Cells

Автор: Hof Martin, Hutterer Rudolf, Fidler Vlastimil
Название: Fluorescence Spectroscopy in Biology / Advanced Methods and their Applications to Membranes, Proteins, DNA, and Cells
ISBN: 354022338X ISBN-13(EAN): 9783540223382
Издательство: Springer
Цена: 8851 р.
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Описание: Volume 3 of this new series focuses on brandnew research and applications in biology, biophysics and other fields of life sciences. Many frontline researcher have contributed to this highly attractive and interdisciplinary volume which spans the entire field of present fluorescence spectroscopy including nanotechnology, membrane and DNA studies and fluorescence imaging in cancer research.
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Amyloid Proteins

Автор: Sigurdsson Einar M.
Название: Amyloid Proteins
ISBN: 1588293378 ISBN-13(EAN): 9781588293374
Издательство: Springer
Цена: 6926 р.
Наличие на складе: Нет в наличии.
Описание: A proven collection of readily reproducible techniques for studying amyloid proteins and their involvement in the etiology, pathogenesis, diagnosis, and therapy of amyloid diseases. The contributors provide methods for the preparation of amyloid and its precursors (oligomers and protofibrils), in vitro assays and analytical techniques for their study, and cell culture models and assays for the production of amyloid proteins. Additional chapters present readily reproducible techniques for amyloid extraction from tissue, its detection in vitro and in vivo, as well as nontransgenic methods for developing amyloid mouse models. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
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G Proteins, Receptors, and Disease

Автор: Spiegel Allen M.
Название: G Proteins, Receptors, and Disease
ISBN: 0896034305 ISBN-13(EAN): 9780896034303
Издательство: Springer
Цена: 9236 р.
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Описание: This collection of cutting-edge chapters summarizes in depth the state of our knowledge today concerning how cells communicate via G protein-coupled signal transduction and how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function of a particular G protein or receptor, lists possible mutations, and discusses fully the molecular pathogenesis of associated diseases. Full advantage is taken of insights from artificially created disorders using transgenic and gene knockout approaches. Diagnostic and therapeutic implications are also discussed where relevant. In its unique blend of basic science and clinical medicine, G Proteins, Receptors, and Disease offers deep insights into the physiological significance of this key signal transduction pathway and into the molecular basis of diseases ranging from obesity to malignancy.
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HPLC of Peptides and Proteins / Methods and Protocols

Автор: Aguilar Marie-Isabel
Название: HPLC of Peptides and Proteins / Methods and Protocols
ISBN: 0896039773 ISBN-13(EAN): 9780896039773
Издательство: Springer
Цена: 7311 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Hands-on experts from academia and industry comprehensively describe how to successfully perform all the critical HPLC techniques needed for the analysis of peptides and proteins. The methods range from commonly used techniques to those for capillary to large-scale preparative isolation. The authors have also presented a number of specific applications as case studies to illustrate the analytical approaches to a particular separation or assay challenge, with examples drawn from contemporary fields in biochemistry and biotechnology.
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Mass Spectrometry of Proteins and Peptides

Автор: Chapman John R.
Название: Mass Spectrometry of Proteins and Peptides
ISBN: 089603609X ISBN-13(EAN): 9780896036093
Издательство: Springer
Цена: 8466 р.
Наличие на складе: Нет в наличии.
Описание: John R. Chapman recreates the success of his earlier acclaimed book (Protein and Peptide Analysis by Mass Spectrometry, 1996) with a major new collection of cutting-edge methods in the analysis of proteins and peptides. Contributed by well-established investigators, each chapter provides background information before guiding the researcher step-by-step through the experimental process, with detailed instructions to help assure experimental success. The applications covered range widely and include protein sequencing, higher-order structure determination, epitope mapping, kinetics, quantitation, glycosylation analysis, and bacterial typing. Authoritative and eminently practical, Mass Spectrometry of Proteins and Peptides demonstrates the full scope of this versatile analytical technique. All protein chemists and biochemists, as well as bioanalytical scientists, who want to exploit these powerful methods in their work, will find this book indispensable.
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Molecular Modeling of Proteins

Автор: Kukol Andreas
Название: Molecular Modeling of Proteins
ISBN: 1588298647 ISBN-13(EAN): 9781588298645
Издательство: Springer
Цена: 6156 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: offers introductions and methods applicable to problems faced by non-specialists - especially those new to the software packages used in molecular modeling. This book provides tips on troubleshooting and avoiding common pitfalls, along with chapters covering a range of subjects ranging from free energy calculation to applications for drug design.
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Therapeutic Proteins / Methods and Protocols

Автор: Smales C. Mark, James David C.
Название: Therapeutic Proteins / Methods and Protocols
ISBN: 1588293904 ISBN-13(EAN): 9781588293909
Издательство: Springer
Цена: 11546 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: World-class researchers share their innovative and proven techniques for the production of therapeutic proteins downstream of the discovery stage. The methods use a variety of sources for producing therapeutic proteins, including bacterial and yeast expression systems, and insect and mammalian cells, and then cover the purification of the resulting protein using both state-of-the-art and traditional methods, such as those sourced from plasma. Additional chapters offer methods for the characterization of therapeutic proteins throughout the production process, along with methods and strategies for viral inactivation and protein formulation. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
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Proteins, Peptides, and Amino Acids SourceBook

Автор: White John Stephen, White Dorothy Chong
Название: Proteins, Peptides, and Amino Acids SourceBook
ISBN: 0896036138 ISBN-13(EAN): 9780896036130
Издательство: Springer
Цена: 9236 р.
Наличие на складе: Нет в наличии.
Описание: Building on the success of their Source Book of Enzymes, John and Dorothy Chong White have assembled an exhaustive catalog of over 26,000 commercially available proteins, peptides, and amino acids, all arranged alphabetically and by sequence for fast access, and each replete with technical details and vendor information. Compounds can be easily located by either directly searching the appropriate section by chemical name, or by consulting the general index by name, synonym, or derivative formula. Peptides with known sequences may be found alphabetically by basic sequence (no modification) or by consulting the Sequences Index. A Glossary of Abbreviations and Acronyms makes it possible to quickly find compounds by their common names. Once the desired compound is located, the selection of the right product for an application is facilitated by presenting its specific technical data in an easy-to-use format that permits comparison across sources. This valuable data covers sequence, sequence modification, chemical derivatives, preparation form, purity, composition, activity, functionality, temperature/pH optima, as well as product notes that list known applications, compound importance, and literature references. The selected compound may then be ordered by using the catalog number provided and the Reagent Suppliers Index.
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Downstream Processing of Proteins / Methods and Protocols

Автор: Desai Mohamed A.
Название: Downstream Processing of Proteins / Methods and Protocols
ISBN: 0896035646 ISBN-13(EAN): 9780896035645
Издательство: Springer
Цена: 8081 р.
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Описание: Mohamed A. Desai and a team of experienced biotechnologists review both conventional and novel isolation techniques used in industrial applications for the downstream processing of protein molecules. These techniques include primary and secondary separations during the isolation of biomolecules, as well as unique laboratory-scale research methods from academia with a potential for scale-up. Also treated are various strands of the downstream biological process essential for a successful product license application, including both the validation of DSP stages, and the design and validation of viral clearance stages during the purification process. Downstream Processing of Proteins: Methods and Protocols provides scientists everywhere, but particularly in the biopharmaceutical and biotechnology industry, with a much-needed introduction to this critical technology.
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