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Process Development: Fine Chemicals from Grams to Kilograms, Lee, Stan;Robinson, Graham (both of Zeneca Pharmac

Process Development: Fine Chemicals from Grams to Kilograms

Автор: Lee, Stan;Robinson, Graham (both of Zeneca Pharmac
Название:  Process Development: Fine Chemicals from Grams to Kilograms   (Развитие процесса: химикаты от граммов до килограммов)
Издательство: Oxford Academ
Классификация:
Органическая химия
Физическая химия
Промышленная химия

ISBN: 0198558244
ISBN-13(EAN): 9780198558248
ISBN: 0-19-855824-4
ISBN-13(EAN): 978-0-19-855824-8
Обложка/Формат: Paperback
Страницы: 96
Вес: 0.19 кг.
Дата издания: 20.07.1995
Серия: Oxford chemistry primers
Язык: ENG
Иллюстрации: Chemical structures
Размер: 24.64 x 18.85 x 0.56 cm
Читательская аудитория: Tertiary education (us: college)
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. In this concise text the authors use real examples to show the problems which may be encountered in scaling up chemical syntheses and the ways in which these problems may be overcome. The major part of the book is devoted to genuine case histories from ICI/Zeneca Pharmaceuticals. Through a range of carefully chosen examples, the book explains how it is possible to synthesise multi-kilogram quantities of a new organic compound which have been made in the laboratory only on the milligram scale. A wide range of aliphatic, aromatic, and heterocyclic compounds is covered. The book will be of particular value to research chemists who are involved in the development phase of novel compounds and to advanced undergraduate and postgraduate students interested in the fine chemicals industry.
Дополнительное описание: Кол-во стр.: 92
Формат: 246 x 189
Дата издания: 1995
Илюстрации: Chemical structures, bibliog
Вес: 190
Круг читателей: academic, specialist



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Managing the Clinical Drug Development Process

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Описание: It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to a number of factors that should be, at least partially, predictable from preclinical testing. Computer Techniques in Preclinical and Clinical Drug Development asks the question, "How can we use computational methods to improve the success rate in drug development?" It shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

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Описание: Preclinical Drug Development, Second Edition discusses the broad realm of preclinical drug development, ranging from assessment of pharmacology and toxicology to the industry trends and regulatory expectations and requirements that support clinical trials. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.

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Описание: This new title describes the tests and processes undertaken to bring new medicines and medical devices to the market, and the work of the government agencies which ensure products of the highest standard. The text covers the controls to prove quality, safety, and efficacy prior to marketing, and postmarketing pharmacovigilance requirements.
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ISBN: 3527310894 ISBN-13(EAN): 9783527310890
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Наличие на складе: Поставка под заказ.
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Описание: The Process of New Drug Discovery and Development, Second Edition presents a practical methodology and up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. This new edition reports on the scientific advances in new drug discovery and development for areas such as combinatorial chemistry, screening technologies, metabonomics, and preclinical testing. It also greatly expands its focus on the business aspects of bringing drugs to market and offers coverage of essential topics for companies involved in drug development, such as the financial aspects of establishing a start-up pharmaceutical enterprise, the regulatory process, risk assessment, liability and litigation, and patent law.
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