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Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology, Jose Luis Millan

Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology

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Автор: Jose Luis Millan
Название:  Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology   (Щелочные фосфатазы млекопитающих: от биологии до применений в медицине и биотехнологии)
Издательство: Wiley
Классификация:
Химия
Биология и естественные науки
Биохимия

ISBN: 3527310797
ISBN-13(EAN): 9783527310791
ISBN: 3-527-31079-7
ISBN-13(EAN): 978-3-527-31079-1
Обложка/Формат: Hardback
Страницы: 338
Вес: 0.776 кг.
Дата издания: January 20, 2006
Язык: ENG
Иллюстрации: Illustrations (some col.)
Размер: 246 x 186 x 22
Читательская аудитория: Professional & vocational
Подзаголовок: From biology to applications in medicine and biotechnology
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: the structure, regulation and expression of the AP genes; the three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes; the phenotypic abnormalities of the different AP knockout mice; and our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.
Дополнительное описание: Кол-во стр.: 300
Формат: 240 x 170
Дата издания: 2005
Круг читателей: academic, specialist; research, professional


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Protein Phosphatases

Автор: Arino JoaquГ­n, Alexander Denis R.
Название: Protein Phosphatases
ISBN: 3540205608 ISBN-13(EAN): 9783540205609
Издательство: Springer
Цена: 28413 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: This book provides an up-to-date and comprehensive overview of protein phosphatase research, a rapidly evolving field with increasing importance in our understanding of the molecular basis of cell biology and of pathological processes. The book covers dephosphorylation processes involving serine/threonine, as well as tyrosine and histidine residues, and aims to be a useful resource for both the advanced reader as well as the newcomer to the field. It is also valuable for those working in the pharmaceutical and Biotech industries.

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Protein Phosphatases,366

Автор: Susanne Klumpp
Название: Protein Phosphatases,366
ISBN: 0121822699 ISBN-13(EAN): 9780121822699
Издательство: Elsevier Science
Цена: 13090 р.
Наличие на складе: Поставка под заказ.

Описание: Protein phosphatases are a group of enzymes responsible for the dephosphorylation of various proteins and enzymes in a cell. This role is an extremely important one since protein phosphorylation and dephosphorylation is required for the regulation of a large number of cellular activities.

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Protein Tyrosine Phosphatases

Автор: Pulido
Название: Protein Tyrosine Phosphatases
ISBN: 1493937448 ISBN-13(EAN): 9781493937448
Издательство: Springer
Цена: 8469 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: This book provides coverage, methodology, and laboratory protocols on the more essential aspects of protein tyrosine phosphatase (PTP) function and regulation, including the use of standardized in vitro functional assays, suitable cell systems, and animal and microorganism models. Chapters covering state-of-the-art technical approaches suitable to decipher the physiologic roles of PTPs, and their involvement in tissue-specific functions, are also included, which will be of utility for both newcomers and experienced researchers in the field of tyrosine- and phosphoinositide- phosphorylation/dephosphorylation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Protein Tyrosine Phosphatases: Methods and Protocols aims to aid researchers in better defining the common and individual features of the PTP family members and translating this knowledge into PTP-based therapy for human disease.
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Protein Tyrosine Phosphatases in Cancer

Автор: Neel
Название: Protein Tyrosine Phosphatases in Cancer
ISBN: 1493936476 ISBN-13(EAN): 9781493936472
Издательство: Springer
Цена: 12952 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: This book aims to bridge the gap in understanding how protein-tyrosine phosphatases (PTPs), which carry out the reverse reaction of tyrosine phosphorylation, feature in cancer cell biology. The expertly authored chapters will first review the general features of the PTP superfamily, including their overall structure and enzymological properties; use selected examples of individual PTP superfamily members, to illustrate emerging data on the role of PTPs in cancer; and will review the current status of PTP-based drug development efforts.

Protein Tyrosine Phosphatases in Cancer,from renowned researchers Benjamin Neel and Nicholas Tonks, is invaluable reading for researchers in oncology, stem cell signaling,and biochemistry.
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Tyrosine Phosphoprotein Phosphatases 2/e (Paperback)

Автор: Goldstein, Barry J.
Название: Tyrosine Phosphoprotein Phosphatases 2/e (Paperback)
ISBN: 0198502478 ISBN-13(EAN): 9780198502470
Издательство: Oxford Academ
Цена: 7450 р.
Наличие на складе: Поставка под заказ.

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Mammalian Cell Biotechnology A Practical Approach (Paperback)

Автор: Butler, M.
Название: Mammalian Cell Biotechnology A Practical Approach (Paperback)
ISBN: 019963209X ISBN-13(EAN): 9780199632091
Издательство: Oxford Academ
Цена: 7450 р.
Наличие на складе: Поставка под заказ.

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Genomics and Systems Biology of Mammalian Cell Culture

Автор: Hu
Название: Genomics and Systems Biology of Mammalian Cell Culture
ISBN: 3642283497 ISBN-13(EAN): 9783642283499
Издательство: Springer
Цена: 25186 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: Transcriptome Analysis, by Frank Stahl, Bernd Hitzmann, Kai Mutz, Daniel Landgrebe, Miriam L?bbecke, Cornelia Kasper, Johanna Walter und Thomas Scheper Transcriptome Data Analysis for Cell Culture Processes, by Marlene Castro-Melchor, Huong Le und Wei-Shou Hu Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, by Ziomara P. Gerdtzen Metabolic Flux Analysis in Systems Biology of Mammalian Cells, by Jens Niklas und Elmar Heinzle Advancing Biopharmaceutical Process Development by System-Level Data Analysis and Integration of Omics Data, by Jochen Schaub, Christoph Clemens, Hitto Kaufmann und Torsten W. Schulz Protein Glycosylation and Its Impact on Biotechnology, by Markus Berger, Matthias Kaup und V?ronique Blanchard Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects, by Patrick Hossler Modeling of Intracellular Transport and Compartmentation, by Uwe Jandt und An-Ping Zeng Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective, by L. Botezatu, S. Sievers, L. Gama-Norton, R. Schucht, H. Hauser und D. Wirth.

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Mammalian Toxicology

Автор: Abou-Donia
Название: Mammalian Toxicology
ISBN: 1119940419 ISBN-13(EAN): 9781119940418
Издательство: Wiley
Цена: 7040 р.
Наличие на складе: Поставка под заказ.

Описание: Mammalian Toxicology surveys chemical agents and examines how such chemicals impact on human health, emphasizing the importance in minimizing environmental exposure to chemical and physical hazards in our homes, communities and workplaces through such media as contaminated water, soil and air. Starting with the basic principles on a wide range of toxic agents, this textbook describes how they enter the body, their mechanisms of action once inside, and strategies for diagnosis, prevention, and treatment. Topics covered include: General principles of toxicology: pharmacological and toxicological principles underpinning the study of toxicology, risk assessments and mechanisms of cell death Disposition: routes of chemical exposures, entry into the body and various tissues, storage, metabolic biotransformation and elimination, with examples of various toxicants Toxic agents: the occurrences, disposition in the body, health effects, toxic mechanisms, antidotes and treatments of a range of agents including pesticides, metals, solvents, gases, nanomaterials, food components and additives, pharmaceuticals, drugs of abuse, natural toxins, endocrine disruptors, radiation, and warfare weapons Toxic effects: including neurotoxicity, developmental toxicity, immunotoxicity, teratogenicity, male and female reproductive toxicity, mutagenicity, carcinogenicity, pulmonary toxicity, cardiovascular toxicity, hepatotoxicity, gastrointestinal toxicity and cardiovascular toxicity Toxicology and society: epidemiological studies of chemical–induced diseases in human populations, and a vision for toxicology in the 21st century. Mammalian Toxicology is an essential primer for students of toxicology, biochemistry, biology, medicine and chemistry. It is also appropriate for professional toxicologists in research or regulatory affairs, and anyone who needs to understand the adverse effects of toxic agents on the human body.

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Protein Expression in Mammalian Cells

Автор: Hartley
Название: Protein Expression in Mammalian Cells
ISBN: 1617793515 ISBN-13(EAN): 9781617793516
Издательство: Springer
Цена: 9239 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: Through all of the recent progress provided by high throughput DNA sequencing technologies, it has become clearer and clearer that the study of proteins and protein organelles will be the key to unlocking our ability to manipulate cells and intervene in human disease.  In Protein Expression in Mammalian Cells: Methods and Protocols, expert researchers in the field present a compendium of vital techniques to further our knowledge of mammalian protein expression.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and concise, Protein Expression in Mammalian Cells: Methods and Protocols will aid scientists seeking to delve deeper into our own biology through the medium of other mammalian cells and proteins.

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A Laboratory Guide to the Mammalian Embryo (Paperback)

Автор: Gardner, David K.; Lane, Michelle; Watson, Andrew
Название: A Laboratory Guide to the Mammalian Embryo (Paperback)
ISBN: 0195142268 ISBN-13(EAN): 9780195142266
Издательство: Oxford Academ
Цена: 3724 р.
Наличие на складе: Поставка под заказ.

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Gene Transfer and Expression in Mammalian Cells,38

Автор: S.C. Makrides
Название: Gene Transfer and Expression in Mammalian Cells,38
ISBN: 044451371X ISBN-13(EAN): 9780444513717
Издательство: Elsevier Science
Цена: 20405 р.
Наличие на складе: Поставка под заказ.

Описание: The production of proteins in mammalian cells is an important tool in numerous scientific and commercial areas. For example, proteins for human therapy, vaccination or diagnostic applications are typically produced in mammalian cells. Gene cloning, protein engineering, biochemical and biophysical characterization of proteins also require the use of gene expression in mammalian cells.

Other applications in widespread use involve screening of libraries of chemical compounds in drug discovery, and the development of cell-based biosensors. This book presents a state-of-the-art comprehensive coverage of the technical aspects of gene expression in mammalian cells, written by experienced scientists working at the forefront of the field.

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Gene Delivery to Mammalian Cells / Volume 1: Nonviral Gene Transfer Techniques

Автор: Heiser William C.
Название: Gene Delivery to Mammalian Cells / Volume 1: Nonviral Gene Transfer Techniques
ISBN: 1588290867 ISBN-13(EAN): 9781588290861
Издательство: Springer
Цена: 11164 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.

Описание: Highly experienced researchers describe in step-by-step detail methods that have proven most useful in delivering genes to mammalian cells. Volume 1: Nonviral Gene Transfer Techniques focuses on gene delivery by a variety of chemical and physical methods, including ultrasound, biolistics, peptides, PNA clamps, liposomes, microinjection, electroporation, particle bombardment, dendrimers, and hydrodynamics. An accompanying volume, Volume 2: Viral Gene Transfer Techniques, details procedures for delivering genes to cells in vitro and in vivo, including the use of lentiviral vectors.

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