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In Situ Detection of DNA Damage / Methods and Protocols, Didenko Vladimir V.

In Situ Detection of DNA Damage / Methods and Protocols

Автор: Didenko Vladimir V.
Название:  In Situ Detection of DNA Damage / Methods and Protocols   (Внутреннее обнаружение повреждений ДНК, методы и протоколы)
Издательство: Springer
Классификация:
Клеточная биология

ISBN: 0896039528
ISBN-13(EAN): 9780896039520
ISBN: 0-89603-952-8
ISBN-13(EAN): 978-0-89603-952-0
Обложка/Формат: Hardcover
Страницы: 336
Вес: 0.68 кг.
Дата издания: 2002
Серия: Methods in Molecular Biology
Язык: ENG
Размер: 23.47 x 16.10 x 2.41 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: In In Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single- and double-stranded DNA breaks in tissue sections while using polymerases, ligases, nucleases, and kinases. There are also novel instrumental techniques that use ultrasound for in vivo and in situ detection of apoptotic DNA damage, and in situ applications of flow and laser-scanning cytometry for analysis of DNA strand breaks and apoptosis. State-of-the-art and highly practical, In Situ Detection of DNA Damage: Methods and Protocols presents for the first time a complete set of enzymatic methods for determining DNA breaks, and will greatly facilitate the work of all those studying the in situ detection of DNA damage and the labeling of apoptotic cells.
Дополнительное описание: Формат: 229x152
Илюстрации: 33
Круг читателей: Molecular biologists, cell biologists, pathologists, embryologists, toxicologists, radiobiologists, experimental and clinical pathologists, experimental pharmacologists, research oncologists, drug design specialists, and environmental scientists
Ключевые слова:
Язык: eng



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In Situ Detection of DNA Damage

Автор: Vladimir V. Didenko (Ed.)
Название: In Situ Detection of DNA Damage
ISBN: 1603274081 ISBN-13(EAN): 9781603274081
Издательство: Springer
Цена: 7312 р.
Наличие на складе: Нет в наличии.
Описание: Recent advances in organic chemistry, fluorescent microscopy, and materials science have created an entirely new range of techniques and probes for imaging DNA damage in molecular and cellular biology. In DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols, expert researchers explore the latest advances in the area, covering both recent and established techniques to detect and quantify DNA damage at scales ranging from subcellular to the level of a whole live organism. Chapters present all major assays used in molecular and cellular biology for the labeling of DNA damage in situ, ex vivo, and in vivo. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and current, DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols is an essential handbook for novice and experienced researchers in a variety of fields, including molecular and cellular biology, experimental and clinical pathology, toxicology, radiobiology, oncology, embryology, experimental pharmacology, drug design, and environmental science.
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Postlabelling Methods for the Detection of DNA Adducts

Автор: Phillips, D.H., Castegnaro, M., Bartsch, H.
Название: Postlabelling Methods for the Detection of DNA Adducts
ISBN: 9283221249 ISBN-13(EAN): 9789283221241
Издательство: WHO Press
Цена: 3105 р.
Наличие на складе: Невозможна поставка.
Описание: This volume describes developments in the methodology and applications of the highly sensitive postlabelling methods that analyze interactions between genes and toxic substances.
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Free-Radical-Induced DNA Damage and Its Repair / A Chemical Perspective

Автор: Sonntag Clemens von
Название: Free-Radical-Induced DNA Damage and Its Repair / A Chemical Perspective
ISBN: 3540261206 ISBN-13(EAN): 9783540261209
Издательство: Springer
Цена: 19943 р.
Наличие на складе: Нет в наличии.
Описание: Both chemists and molecular biologists will find this an invaluable reference work for the study of free radical induced DNA damage and its repair.
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DNA Damage and Repair / Volume III: Advances from Phage to Humans

Автор: Nickoloff Jac A., Hoekstra Merl F.
Название: DNA Damage and Repair / Volume III: Advances from Phage to Humans
ISBN: 0896038033 ISBN-13(EAN): 9780896038035
Издательство: Springer
Цена: 8467 р.
Наличие на складе: Нет в наличии.
Описание: Jac A. Nickoloff and Merl F. Hoekstra update and expand their two earlier acclaimed volumes (Vol. I: DNA Repair in Prokaryotes and Lower Eukaryotes and Vol. II: DNA Repair in Higher Eurkaryotes) with cutting-edge reviews by leading authorities of primary experimental findings about DNA repair processes in cancer biology. The reviews cover a wide range of topics from viruses and prokaryotes to higher eukaryotes, and include several new topics, among them the role of recombination in replication of damaged DNA, X-ray crystallographic analysis of DNA repair protein structures, DNA repair proteins and teleomere function, and the roles of BRCA1 and BRCA2 in DNA repair. Authoritative and up-to-date, DNA Damage and Repair, Vol. III: Advances from Phage to Humans surveys the rapidly moving research in DNA damage and repair, and explains the important functional relationships among different DNA repair pathways and the relationship between DNA repair pathways, cancer etiology, and cancer therapies.
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DNA Damage and Repair / Volume I: DNA Repair in Prokaryotes and Lower Eukaryotes

Автор: Nickoloff Jac A., Hoekstra Merl F.
Название: DNA Damage and Repair / Volume I: DNA Repair in Prokaryotes and Lower Eukaryotes
ISBN: 0896033562 ISBN-13(EAN): 9780896033566
Издательство: Springer
Цена: 9237 р.
Наличие на складе: Нет в наличии.
Описание: Award-winning researchers review of key aspects of DNA repair in a wide variety of organisms, including all-important model systems. The book focuses on DNA damage and repair in prokaryotic and model eukaryotic systems, emphasizing the significant progress that has been made in the past five years. Each chapter has undergone a rigorous peer-review cycle to ensure definitive and comprehensive treatment. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in cell cycle regulation.
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Recombinant Protein Protocols / Detection and Isolation

Автор: Tuan Rocky S.
Название: Recombinant Protein Protocols / Detection and Isolation
ISBN: 089603481X ISBN-13(EAN): 9780896034815
Издательство: Springer
Цена: 8082 р.
Наличие на складе: Нет в наличии.
Описание: Leading researchers and experts present wide-ranging methods for detecting and isolating expressed gene products-recombinant proteins. These state-of-the-art techniques describe a large number of molecular tags and labels, including enzymes, ligand-binding moieties, and immunodetectable molecules. There are also methods to detect interactive proteins and gene expression-mediated alterations in cellular activity, as well as chapters on in situ detection of gene expression. When combined with a companion volume by the same editor, Recombinant Gene Expression Protocols, both volumes guide the research worker through the entire journey of recombinant gene expression.
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Recombinant Protein Protocols / Detection and Isolation

Автор: Tuan Rocky S.
Название: Recombinant Protein Protocols / Detection and Isolation
ISBN: 0896034003 ISBN-13(EAN): 9780896034006
Издательство: Springer
Цена: 6157 р.
Наличие на складе: Нет в наличии.
Описание: Leading researchers and experts present wide-ranging methods for detecting and isolating expressed gene products-recombinant proteins. These state-of-the-art techniques describe a large number of molecular tags and labels, including enzymes, ligand-binding moieties, and immunodetectable molecules. There are also methods to detect interactive proteins and gene expression-mediated alterations in cellular activity, as well as chapters on in situ detection of gene expression. When combined with a companion volume by the same editor, Recombinant Gene Expression Protocols, both volumes guide the research worker through the entire journey of recombinant gene expression.
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PCR Mutation Detection Protocols

Автор: Theophilus Bimal D. M., Rapley Ralph
Название: PCR Mutation Detection Protocols
ISBN: 0896036170 ISBN-13(EAN): 9780896036178
Издательство: Springer
Цена: 5618 р.
Наличие на складе: Нет в наличии.
Описание: Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.
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DNA Damage and Repair / Volume II: DNA Repair in Higher Eukaryotes

Автор: Nickoloff Jac A., Hoekstra Merl F.
Название: DNA Damage and Repair / Volume II: DNA Repair in Higher Eukaryotes
ISBN: 089603500X ISBN-13(EAN): 9780896035003
Издательство: Springer
Цена: 9237 р.
Наличие на складе: Нет в наличии.
Описание: Cutting edge reviews by leading researchers illuminate key aspects of DNA repair in mammalian systems and its relationship to human genetic disease and cancer. Major topics include UV and X-Ray repair, repair of chemical damage, recombinational repair, mismatch repair, transcription-repair coupling, and the role of DNA repair in disease prevention. Extensive up-to-date references and rigorous peer-review of each chapter make this volume definitive and bring it to the active frontiers of research.
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Medical Biofilms, Detection, Prevention and Control

Автор: Jana Jass
Название: Medical Biofilms, Detection, Prevention and Control
ISBN: 0471988677 ISBN-13(EAN): 9780471988670
Издательство: Wiley
Цена: 12672 р.
Наличие на складе: Поставка под заказ.
Описание: Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortaty. * This will be the first book dedicated to medical biofilms. * It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.
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PCR Detection of Microbial Pathogens

Автор: Mark Wilks (Ed.)
Название: PCR Detection of Microbial Pathogens
ISBN: 1603273522 ISBN-13(EAN): 9781603273527
Издательство: Springer
Цена: 7312 р.
Наличие на складе: Нет в наличии.
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PCR Detection of Microbial Pathogens

Автор: Mark Wilks (Ed.)
Название: PCR Detection of Microbial Pathogens
ISBN: 1603273484 ISBN-13(EAN): 9781603273480
Издательство: Springer
Цена: 5902 р.
Наличие на складе: Нет в наличии.
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