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A Practical Approach to Microarray Data Analysis, Berrar Daniel P., Dubitzky Werner, Granzow Martin

A Practical Approach to Microarray Data Analysis

Автор: Berrar Daniel P., Dubitzky Werner, Granzow Martin
Название:  A Practical Approach to Microarray Data Analysis   (Практический подход к анализу данных)
Издательство: Springer
Классификация:
Биологические науки: общие вопросы
Биохимия
Структуры данных
Компьютерная сертификация
Искусственный интеллект

ISBN: 1402072600
ISBN-13(EAN): 9781402072604
ISBN: 1-402-07260-0
ISBN-13(EAN): 978-1-402-07260-4
Обложка/Формат: Hardcover
Страницы: 384
Вес: 0.829 кг.
Дата издания: 2003
Язык: ENG
Размер: 22.96 x 17.17 x 2.77 cm
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: A Practical Approach to Microarray Data Analysis is for all life scientists, statisticians, computer experts, technology developers, managers, and other professionals tasked with developing, deploying, and using microarray technology including the necessary computational infrastructure and analytical tools. The book addresses the requirement of scientists and researchers to gain a basic understanding of microarray analysis methodologies and tools. It is intended for students, teachers, researchers, and research managers who want to understand the state of the art and of the presented methodologies and the areas in which gaps in our knowledge demand further research and development. The book is designed to be used by the practicing professional tasked with the design and analysis of microarray experiments or as a text for a senior undergraduate- or graduate level course in analytical genetics, biology, bioinformatics, computational biology, statistics and data mining, or applied computer science. Key topics covered include: -Format of result from data analysis, analytical modeling/experimentation; -Validation of analytical results; -Data analysis/Modeling task; -Analysis/modeling tools; -Scientific questions, goals, and tasks; -Application; -Data analysis methods; -Criteria for assessing analysis methodologies, models, and tools.
Описание: Addresses the requirement of scientists and researchers to gain an understanding of microarray analysis methodologies and tools. This work is designed as a text for a senior undergraduate- or graduate level course in analytical genetics, biology, bioinformatics, computational biology, statistics and data mining, or applied computer science.
Дополнительное описание: Круг читателей: Life scientists, statisticians, computer experts, technology developers, managers
Язык: eng



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Advanced analysis of gene expression microarray data

Автор: Zhang Aidong
Название: Advanced analysis of gene expression microarray data
ISBN: 9812566457 ISBN-13(EAN): 9789812566454
Издательство: World Scientific Publishing
Цена: 1092 р.
Наличие на складе: Есть (4 шт.)
Описание: This book focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data.Biomedical researchers will find this book invaluable for learning the cutting-edge methods for analyzing gene expression microarray data. Specifically, the coverage includes the following state-of-the-art methods:Ȣ Gene-based analysis: the latest novel clustering algorithms to identify co-expressed genes and coherent patterns in gene expression microarray data setsȢ Sample-based analysis: supervised and unsupervised methods for the reduction of the gene dimensionality to select significant genes. A series of approaches to disease classification and discovery are also describedȢ Pattern-based analysis: methods for ascertaining the relationship between (subsets of) genes and (subsets of) samples. Various novel pattern-based clustering algorithms to find the coherent patterns embedded in the sub-attribute spaces are discussedȢ Visualization tools: various methods for gene expression data visualization. The visualization process is intended to transform the gene expression data set from high-dimensional space into a more easily understood two- or three-dimensional space.
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Nonlinear H2/H-Infinity Constrained Feedback Control / A Practical Design Approach Using Neural Networks

Автор: Abu-Khalaf Murad, Huang Jie, Lewis Frank L.
Название: Nonlinear H2/H-Infinity Constrained Feedback Control / A Practical Design Approach Using Neural Networks
ISBN: 1846283493 ISBN-13(EAN): 9781846283499
Издательство: Springer
Цена: 11549 р.
Наличие на складе: Нет в наличии.
Описание: Modern aerospace, automotive, nautical, industrial, microsystem-assembly and robotic systems are becoming more and more complex. High-performance vehicles no longer have built-in error safety margins, but are inherently unstable by design to allow for more flexible maneuvering options. With the push towards better performance in terms of greater accuracy and faster speed of response, control demands are increasing. The combination of highly nonlinear dynamics, relaxed static stability, and tight performance specifications places increasing demands on the design of feedback systems for control. Current control system design techniques have difficulty in meeting these demands.
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Liposomes: A Practical Approach

Название: Liposomes: A Practical Approach
ISBN: 0199636540 ISBN-13(EAN): 9780199636549
Издательство: Oxford Academ
Цена: 7450 р.
Наличие на складе: Поставка под заказ.
Описание: This book is a collection of experimental protocols from an area of pharmaceutical research that is essential for the development of new, highly specific drugs as well as for the exploration of completely new therapeutic approaches to disease treatments.
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Epitope Mapping: A Practical Approach

Название: Epitope Mapping: A Practical Approach
ISBN: 0199636532 ISBN-13(EAN): 9780199636532
Издательство: Oxford Academ
Цена: 12709 р.
Наличие на складе: Поставка под заказ.
Описание: Epitope Mapping covers all the major methods for the identification and definition of epitopes. The Pepscan assay is used to define B cell epitopes and makes use of synthetic peptides but can only be used if the amino acid sequence is known. It can be adapted for the delineation of both helper T cells and cytotoxic T cells. The identification of combined B and T cell epitopes can also be achieved using synthetic peptides. There are other methodologies for analysing for cytotxic T cell epitopes such as the purification of antigens presented by MHC class I molecules and expression cloning. Site directed mutagenesis is also a powerful tool in epitope mapping and can be used to evaluate the role of single amino acids in immune complex formation. Protein footprinting makes use of monoclonal antibodies produced by hybridoma technology and relies on the fact that the epitope is protected from cleavage when bound as an antibody-antigen complex. It is only useful for small antigens. Other monoclonal antibody assays such as enzyme linked immunosorbent assay and haemaglutination and slot-blotting may also be used in epitope mapping. Random phage display libraries bring together the genetic and amino acid peptide sequence and can be screened with antibody and the resulting peptide DNA sequenced to confirm the amino acid sequence of a specific eptiope. Investigation of carbohydrates can also be useful to eptitope mapping as deglycosylation can lead to loss of antigenic activity. Epitopes are important to the pharmaceutical industry and wherever appropriate, pharmaceutical applications of the methods described are included. For each method there is a description of the technology, protocols, trouble-shooting, and advice on when to use the method. This book will therefore be invaluable to any researcher involved in epitope mapping.
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Essential Algorithms: A Practical Approach to Computer Algorithms

Автор: Stephens
Название: Essential Algorithms: A Practical Approach to Computer Algorithms
ISBN: 1118612108 ISBN-13(EAN): 9781118612101
Издательство: Wiley
Цена: 4400 р.
Наличие на складе: Поставка под заказ.
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Immunoassays: A Practical Approach

Автор: Gosling
Название: Immunoassays: A Practical Approach
ISBN: 0199637105 ISBN-13(EAN): 9780199637102
Издательство: Oxford Academ
Цена: 7450 р.
Наличие на складе: Поставка под заказ.
Описание: Immunoassays is the first practical volume designed to help any biologist develop an immunoassay of any common format for any suitable analyte. The basic principles are described and the choices of assay types and formats listed. Methods for raising and for characterizing antibodies, for preparing radioactive, enzymatic, fluorescent and other labels, are described. Solid-phase reagents, standards and immunogens are explained, with procedures for their preparation. But
most components can be obtained commercially and comprehensive lists of suppliers are given. Approaches to combining the reagentnd optimizing the required assay are described, including how to eliminate common interferences, and thorough validation procedures are given. Manual and computer methods for the calculation of concentrations are explained. Since only assays that are within control give valid results, a graded and comprehensive approach to internal and external quality assurance
methods
detailed, including how to prepare control samples.

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Post-translational Processing: A Practical Approach

Название: Post-translational Processing: A Practical Approach
ISBN: 0199637954 ISBN-13(EAN): 9780199637959
Издательство: Oxford Academ
Цена: 7012 р.
Наличие на складе: Поставка под заказ.
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Gel Electrophoresis of Proteins: A Practical Approach

Название: Gel Electrophoresis of Proteins: A Practical Approach
ISBN: 0199636400 ISBN-13(EAN): 9780199636402
Издательство: Oxford Academ
Цена: 4645 р.
Наличие на складе: Поставка под заказ.
Описание: This text presents the best methods, hints and tips for core procedures such as one-dimensional polyacrylamide gel electrophoresis, isoelectric focusing, two-dimensional gel electrophoresis, preparative gel electrophoresis, and peptide mapping, with refinements and updates of the procedures.
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HPLC of Macromolecules: A Practical Approach

Автор: Oliver, R.W.A.
Название: HPLC of Macromolecules: A Practical Approach
ISBN: 0199635706 ISBN-13(EAN): 9780199635702
Издательство: Oxford Academ
Цена: 4821 р.
Наличие на складе: Поставка под заказ.
Описание: HPLC stands for high pressure (or performance) liquid chromatography, and is a standard biochemical technique for separating molecules. This volume covers the larger biomolecules - oligosaccharides, glycopeptides, oligonucleotides, polypeptides and proteins.
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MHC : Vol 1. Antigen Processing and Presentation: A Practical Approach

Название: MHC : Vol 1. Antigen Processing and Presentation: A Practical Approach
ISBN: 0199635536 ISBN-13(EAN): 9780199635535
Издательство: Oxford Academ
Цена: 7450 р.
Наличие на складе: Поставка под заказ.
Описание: In the PRACTICAL APPROACH series, Volume 1 of a two-volume introduction, for immunology laboratories, to biochemical and genetic techniques for the study of the structure of major histocompatibility complex proteins and their function as antigen presenting molecules.
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Protein Structure Prediction: A Practical Approach

Название: Protein Structure Prediction: A Practical Approach
ISBN: 0199634963 ISBN-13(EAN): 9780199634965
Издательство: Oxford Academ
Цена: 3945 р.
Наличие на складе: Поставка под заказ.
Описание: The three-dimensional structure of proteins is a key factor in their biological activity. There is a need to be able to predict the structure of a protein once its amino-acid sequence is known. This text presents practical methods of achieving that aim, using computer modelling algorithms.
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Enzyme Assays: A Practical Approach

Название: Enzyme Assays: A Practical Approach
ISBN: 0199638217 ISBN-13(EAN): 9780199638215
Издательство: Oxford Academ
Цена: 12709 р.
Наличие на складе: Поставка под заказ.
Описание: Topics include experimental protocols covering photometric, radiometric, HPLC, and electrochemical assays, along with methods for determining enzyme assays after gel electrophoresis. The theory underlying each method is outlined, together with the instrumentation, sensitivity and sources of error.
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