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Cancer Drug Design and Discovery, Niedle


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Автор: Niedle
Название:  Cancer Drug Design and Discovery
Перевод названия: Лекарства против рака проектирование и открытие
ISBN: 9780123694485
Издательство: Elsevier Science
Классификация:


ISBN-10: 0123694485
Обложка/Формат: Hardback
Страницы: 496
Вес: 1.32 кг.
Дата издания: 30.11.2007
Язык: English
Иллюстрации: Illustrations
Размер: 26.19 x 19.41 x 3.58 cm
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Европейский союз
Описание: Covers available drugs as well as those under development and provides a clinical perspective on trials of anticancer agents. This book also presents drug discovery examples through the use of case histories.


The Organic Chemistry of Drug Design and Drug Action,

Автор: Richard B. Silverman
Название: The Organic Chemistry of Drug Design and Drug Action,
ISBN: 0123820308 ISBN-13(EAN): 9780123820303
Издательство: Elsevier Science
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Цена: 13304.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules.

This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage.

This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.

Antiepileptic Drug Discovery

Автор: Talevi
Название: Antiepileptic Drug Discovery
ISBN: 1493963538 ISBN-13(EAN): 9781493963539
Издательство: Springer
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Цена: 19564.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy. The last section illustrates the potential benefits that network pharmacology and rational drug repurposing could bring to the antiepileptic drug discovery community. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of detailed description and implementation advice to ensure results in the laboratory.

Authoritative and practical, Antiepileptic Drug Discovery: Novel Approaches aims to provide medicinal chemists, pharmacologists, and other researchers with the tools need to further explore the study of pharmacoresistant epilepsy and the discovery of new antiepileptic drugs.
Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Автор: Trabocchi
Название: Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology
ISBN: 1118145658 ISBN-13(EAN): 9781118145654
Издательство: Wiley
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Цена: 22168.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book reviews diversity-oriented synthesis (DOS), a leading and dynamic area in organic chemistry and drug discovery. It first covers key chemical methods for the generation of small molecules according to DOS principles as well as important classes of molecules generated through DOS approaches.

Textbook of Drug Design and Discovery, Fifth Edition

Название: Textbook of Drug Design and Discovery, Fifth Edition
ISBN: 1498702783 ISBN-13(EAN): 9781498702782
Издательство: Taylor&Francis
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Цена: 19906.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.

Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.

The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding).

The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.


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