Hematopoietic Stem Cell Transplantation, Champlin,Richard

Автор: Champlin,Richard
Название:  Hematopoietic Stem Cell Transplantation
Издательство: Informa
Классификация:
Иммунология
Клеточная биология
ISBN: 0824702735
ISBN-13(EAN): 9780824702731
ISBN: 0-8247-0273-5
ISBN-13(EAN): 978-0-8247-0273-1
Обложка: Hardcover
Страницы: 624 pages, illustrat
Вес: 1.21 кг.
Дата издания: 25/07/2000
Серия: Hematology
Язык: ENG
Формат: 267 x 190 mm, 1212 grams
Читательская аудитория: Professional & VocationalPostgraduate, Research &
Рейтинг:
Формат: Книга
Поставляется из:
Описание: This book integrates recent advances in molecular and cell biology of hematopoietic stem cells (HSC) with developments in clinical research in stem cell-based therapy-providing an up-to-date review of novel cytokines and cellular components; animal models; cell preparation, selection, and collection; minimal residual disease and purging; expansion of progenitor cells; allogeneic and autologous transplantation; cellular gene and immunotherapy; and more. Examines key areas for treatment with HSC, including ambulatory care and monitoring, regimen-related toxicities, immunodeficiency and immunization, infection, chronic graft-versus-host and disease, secondary malignancies, and long-term quality of life. Covering stem cell pool regulation and the complex interplay of extrinsic and intrinsic events, Hematopoietic Stem Cell Transplantation summarizes current understanding and development of clinical allogeneic HSC tran plantation.

Discusses the use of allogeneic transplantations with reduced conditioning regimen or mini-transplantation. Considers various strategies for mobilization of HSCs from peripheral blood (PB) of normal donors. Details detection of bone marrow contamination by tumor cells and removal procedures.

Focuses on efforts to increase the ex vivo transduction efficiency of human HSCs with retroviral vectors. Explores the effects of growth factor administration and leukapheresis on PB stem cell donors. Shows the impact of CD34+ cell isolation and the relevance of expansion of HSC from bone marrow for clinical use.

Reveals how minimal residue disease detection assays are crucial for tracking the clinical significance of infused tumor cells. Employs automated fluorescence image cytometry to study early HSC behavior following seeding. Incorporating contributions from over 90 researchers who cite more than 2180 references to encourage continued study, Hematopoietic Stem Cell Transplantation is a blue-chip reference for hematologists, hematopathologists, oncologists, cytotherapists, transplantation immunologists, and molecular biologists.
Наличие на складе:
При оформлении заказа до: 15 сен 2010
Ориентировочная дата поставки: 1 окт 2010
При условии наличия книги в издательстве.

Цена: 6325.00 р.

Добавить в корзину

Add to Wish list