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Pharmaceutical process chemistry for synthesis: rethinking the routes to scale-up, Peter J. Harrington

Pharmaceutical process chemistry for synthesis: rethinking the routes to scale-up

Автор: Peter J. Harrington
Название:  Pharmaceutical process chemistry for synthesis: rethinking the routes to scale-up   (Синтез в производстве фармацевтической продукции)
Издательство: Wiley
Классификация:
Фармакология
Химия
Промышленная химия

ISBN: 047057755X
ISBN-13(EAN): 9780470577554
ISBN: 0-470-57755-X
ISBN-13(EAN): 978-0-470-57755-4
Обложка/Формат: Hardback
Страницы: 369
Вес: 1.158 кг.
Дата издания: 28.01.2011
Язык: ENG
Иллюстрации: Illustrations
Размер: 2.79 cms H x 27.94 cms L x 21.84 cms W
Читательская аудитория: Professional & vocational
Подзаголовок: Rethinking the routes to scale-up
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: There is a need explain that generic versions of a drug may not be manufactured by the same process as brand-name drugs and that the different processes may have dramatically different environmental impacts. Two global forces are at odds today—the push for greener processes and the push for lower drug prices. This book brings this conflict into sharp focus by discussing in detail the published process chemistry for top-selling small molecule drugs. Providing insights about process route selection, choice of reagents, and reaction conditions, Pharmaceutical Process Chemistry for Synthesis guides process chemists in identifying best processes for manufacturing these blockbuster drugs as they lose patent protection. Further, it highlights the strategies and methodology that might be useful for expediting the process research and development of the blockbusters of the future. Written from a refreshingly objective perspective, this book is essential for process chemists who need to devise practical syntheses for increasingly complex drugs in a constantly decreasing time frame.
Описание: Two global forces are at odds today: the push for "greener" processes and the push for lower drug prices. Offering detailed discussions of the published process chemistry of the ten top-selling small molecule drugs in the US in 2007, this book includes information which is usually carefully protected by the current and future manufacturers.
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Pharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules

Автор: Christine Bladon
Название: Pharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules
ISBN: 0471496375 ISBN-13(EAN): 9780471496373
Издательство: Wiley
Цена: 6772 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Explores the way in which peptides, proteins, nucleic acids and carbohydrates use therapeutically. With help of illustrations, this book covers both compounds and how therapeutics exert their influence through an understanding of biological processes.
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Автор: Watson
Название: Pharmaceutical and Medicinal Chemistry. International Edition
ISBN: 0443072337 ISBN-13(EAN): 9780443072338
Издательство: Elsevier Science
Цена: 1616 р.
Наличие на складе: Поставка под заказ.
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Pharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules

Автор: Christine Bladon
Название: Pharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules
ISBN: 0471496367 ISBN-13(EAN): 9780471496366
Издательство: Wiley
Цена: 16984 р.
Наличие на складе: Нет в наличии.
Описание: Explores the way in which peptides, proteins, nucleic acids and carbohydrates use therapeutically. With help of illustrations, this book covers both compounds and how therapeutics exert their influence through an understanding of biological processes.
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Wilson & Gisvold`s Textbook of Organic Medicinal and Pharmaceutical Chemistry

Автор: Block
Название: Wilson & Gisvold`s Textbook of Organic Medicinal and Pharmaceutical Chemistry
ISBN: 0781734819 ISBN-13(EAN): 9780781734813
Издательство: Lippincott Williams & Wilkins
Цена: 4224 р.
Наличие на складе: Поставка под заказ.
Описание: For over half a century, this book has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Eleventh Edition, coverage begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications.
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Автор: Katja Strohfeldt-Venables
Название: Essentials of Inorganic Chemistry: For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry
ISBN: 0470665580 ISBN-13(EAN): 9780470665589
Издательство: Wiley
Цена: 3740 р.
Наличие на складе: Нет в наличии.
Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal–based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective. Written for students of pharmacy and pharmacology, pharmaceutical sciences, medicinal chemistry and other health–care related subjects, this accessible text introduces chemical principles with relevant pharmaceutical examples rather than as stand–alone concepts, allowing students to see the relevance of this subject for their future professions. It includes exercises and case studies.
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ISBN: 0470170867 ISBN-13(EAN): 9780470170861
Издательство: Wiley
Цена: 12848 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Learn how to improve your odds of developing a successful drug candidate Drug development is a highly resource intensive effort. The high attrition rate during nonclinical and especially clinical evaluation demands that the candidate drug selection proc
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ISBN: 0824706250 ISBN-13(EAN): 9780824706258
Издательство: Informa
Цена: 10956 р.
Наличие на складе: Поставка под заказ.
Описание: Focusing on scientific and practical aspects of process scale-up, this resource details the theory and practice of transferring pharmaceutical processes from laboratory scale to the pilot plant and production scale. It covers parenteral and nonparenterel liquids and semi-solids, products derived from biotechnology, dry blending and powder handling, granulation and drying, fluid bed applications, compaction and tableting, and film coating and regulatory requirements for scale-up and postapproval changes. Drawing on the experience of twenty contributing researchers, the book employs dimensional analysis as a unified scientific approach to quantify similar processes on different scales.
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ISBN: 0443072329 ISBN-13(EAN): 9780443072321
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ISBN: 012804148X ISBN-13(EAN): 9780128041482
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Цена: 2768 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
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ISBN: 082471914X ISBN-13(EAN): 9780824719142
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ISBN: 0849398770 ISBN-13(EAN): 9780849398773
Издательство: Taylor&Francis
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Наличие на складе: Поставка под заказ.
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ISBN: 1848166346 ISBN-13(EAN): 9781848166349
Издательство: World Scientific Publishing
Цена: 13396 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging. This book provides an overview of the impact that fluorine has made in the life sciences.
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