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Histopathology of Preclinical Toxicity Studies,, Peter Greaves

Histopathology of Preclinical Toxicity Studies,

Автор: Peter Greaves
Название:  Histopathology of Preclinical Toxicity Studies,   (Петер Гревс: Гистопатология. Доклинические исследования отравлений)
Издательство: Elsevier Science
Классификация:
Медицинское оборудование и методы
Фармакология

ISBN: 0444538569
ISBN-13(EAN): 9780444538567
ISBN: 0-444-53856-9
ISBN-13(EAN): 978-0-444-53856-7
Обложка/Формат: Hardback
Страницы: 892
Вес: 2.532 кг.
Дата издания: 23.11.2011
Серия: Life Sciences
Язык: ENG
Издание: 4 rev ed
Иллюстрации: Approx. 200 illustrations (50 in full color)
Размер: 23.88 x 19.81 x 4.32 cm
Читательская аудитория: Professional & vocational
Подзаголовок: Interpretation and relevance in drug safety evaluation
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: Describes the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. This reference is suitable for those involved in drug safety evaluation, including pathologists, toxicologists, and pharmacologists.
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Histopathology Of Preclinical Toxicity Studies, Interpretation An

Автор: Greaves
Название: Histopathology Of Preclinical Toxicity Studies, Interpretation An
ISBN: 0444505148 ISBN-13(EAN): 9780444505149
Издательство: Elsevier Science
Цена: 22176 р.
Наличие на складе: Нет в наличии.
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Histopathology of preclinical toxicity studies

Автор: Greaves, Peter
Название: Histopathology of preclinical toxicity studies
ISBN: 0444527710 ISBN-13(EAN): 9780444527714
Издательство: Elsevier Science
Цена: 10006 р.
Наличие на складе: Невозможна поставка.
Описание: Covers various aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. This work relates to the preclinical safety assessment of new medicines. It also covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies.
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Preclinical safety evaluation of biopharmaceuticals

Название: Preclinical safety evaluation of biopharmaceuticals
ISBN: 0470108843 ISBN-13(EAN): 9780470108840
Издательство: Wiley
Цена: 14344 р.
Наличие на складе: Нет в наличии.
Описание: Includes an overview of biopharmaceuticals with information on regulation and methods of production. This book discusses the principles of ICH S6 and their implementation in the US, Europe, and Japan. It covers practices in preclinical development and compares safety assessments for small molecules with those for biopharmaceuticals.
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Evaluation of drug candidates for preclinical development

Название: Evaluation of drug candidates for preclinical development
ISBN: 0470044918 ISBN-13(EAN): 9780470044919
Издательство: Wiley
Цена: 8976 р.
Наличие на складе: Нет в наличии.
Описание: Explaining the assessment of potential drug compounds, this title includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. It is suitable for scientists, medicinal chemists, and others working in drug discovery.
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Preclinical Development Handbook: Toxicology

Автор: Shayne Cox Gad
Название: Preclinical Development Handbook: Toxicology
ISBN: 0470248467 ISBN-13(EAN): 9780470248461
Издательство: Wiley
Цена: 16544 р.
Наличие на складе: Нет в наличии.
Описание: This book provides drug safety and toxicology scientists with practical guidance for testing and determining the effectiveness and safety of a new drug candidate. It authoritatively covers the important topics within toxicity testing, pharmacogenomics, and regulations for the preclinical safety testing of drug candidates.
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Preclinical Development Handbook: ADME and Biopharmaceutical Properties

Автор: Shayne Cox Gad
Название: Preclinical Development Handbook: ADME and Biopharmaceutical Properties
ISBN: 0470248475 ISBN-13(EAN): 9780470248478
Издательство: Wiley
Цена: 16544 р.
Наличие на складе: Нет в наличии.
Описание: Guides you through preclinical drug development. This book serves as a reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. It also sets forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.
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Flavonoid Pharmacokinetics: Methods of Analysis, Preclinical and Clinical Pharmacokinetics, Safety, and Toxicology

Автор: Davies
Название: Flavonoid Pharmacokinetics: Methods of Analysis, Preclinical and Clinical Pharmacokinetics, Safety, and Toxicology
ISBN: 0470578718 ISBN-13(EAN): 9780470578711
Издательство: Wiley
Цена: 8976 р.
Наличие на складе: Нет в наличии.
Описание: SETS FORTH A FRAMEWORK FOR THE ANALYSIS AND STUDY OF FLAVONOIDS More and more dietary supplements contain flavonoids. These products are typically viewed as food rather than drug products by regulatory agencies and therefore not subjected to rigorous cl
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Regenerative Medicine II / Clinical and Preclinical Applications

Автор: Yannas Ioannis V.
Название: Regenerative Medicine II / Clinical and Preclinical Applications
ISBN: 3540228683 ISBN-13(EAN): 9783540228684
Издательство: Springer
Цена: 22253 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Organ regeneration, once unknown in adult mammals, is at the threshold of maturity as a clinical method for restoration of organ function in humans. Several laboratories around the world are engaged in the development of new tools such as stem cells and biologically active scaffolds. Others are taking fresh looks at well-known clinical problems of replacement of a large variety of organs: Bone, skin, the spinal cord, peripheral nerves, articular cartilage, the conjunctiva, heart valves and urologic organs. Still other investigators are working out the mechanistic pathways of regeneration and the theoretical implications of growing back organs in an adult. The time has come to present a collection of these efforts from leading practitioners in the field of organ regeneration.
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From Morphological Imaging to Molecular Targeting / Implications to Preclinical Development

Автор: Schwaiger M., Dinkelborg L., Schweinfurth H.
Название: From Morphological Imaging to Molecular Targeting / Implications to Preclinical Development
ISBN: 3540201378 ISBN-13(EAN): 9783540201373
Издательство: Springer
Цена: 4616 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
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Erythropoietins and Erythropoiesis / Molecular, Cellular, Preclinical, and Clinical Biology

Автор: Molineux Graham, Foote Mary A., Elliott Steven
Название: Erythropoietins and Erythropoiesis / Molecular, Cellular, Preclinical, and Clinical Biology
ISBN: 3764375426 ISBN-13(EAN): 9783764375423
Издательство: Springer
Цена: 6929 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: This volume is a one-source guide to the most current information about red blood cell formation and the action of recombinant human erythropoietins. Topics in the fields of erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia will be covered. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed. It is of interest to researchers and clinical investigators in academia and biotechnology and pharmaceutical companies, to clinical research associates, clinical monitors, and physician investigators. This softcover volume is an unchanged second printing of the hardcover edition published in 2003.
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Computer Techniques in Preclinical and Clinical Drug Development

Автор: Jackson
Название: Computer Techniques in Preclinical and Clinical Drug Development
ISBN: 0849376823 ISBN-13(EAN): 9780849376825
Издательство: Taylor&Francis
Цена: 11339 р.
Наличие на складе: Нет в наличии.
Описание: It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to a number of factors that should be, at least partially, predictable from preclinical testing. Computer Techniques in Preclinical and Clinical Drug Development asks the question, "How can we use computational methods to improve the success rate in drug development?" It shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

Short TOC

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Histopathology

Автор: Orchard, Guy; Nation, Brian
Название: Histopathology
ISBN: 0199574340 ISBN-13(EAN): 9780199574346
Издательство: Oxford Academ
Цена: 3242 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Histopathology describes the processes and practices that are central to the role of the histopathologist from pre-sampling to diagnosis to laboratory management. An understanding of the physiology of cells and tissue is vital for the successful identification of clinical conditions and, as such, this book beginnings by laying out the key features of both and their significance for diagnosis. But histopathology relies heavily on optical technology and microscopy is covered in detail from fixing, through staining to light and electron imaging methods. A complete course on the concepts and skills needed for a biomedical scientist to work within a functioning histopathology laboratory.
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Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Com

Автор: J. Thomas August
Название: Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Com
ISBN: 0120329271 ISBN-13(EAN): 9780120329274
Издательство: Elsevier Science
Цена: 4000 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: Conjugation reactions have long been associated with the detoxification of xenobiotics. This volume features a two-color dust jacket, and summarizes the information on: xenobiotic conjugation; drug toxicity, hypersensitivity, and targeting; glutathione-, sulfate conjugate-, and glucuranide conjugate-dependent toxicity; and more.
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In-Vitro Toxicity Testing: Applications to Safety Evaluation

Автор: J. M. Frazier
Название: In-Vitro Toxicity Testing: Applications to Safety Evaluation
ISBN: 0824786149 ISBN-13(EAN): 9780824786144
Издательство: Informa
Цена: 8765 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: This volume focuses on the potential application of in vitro procedures to identify and quantify the toxicological risk to target organs associated with the use of commerical products and therapeutic drugs.;Revealing how the results of in vitro toxicity testing can be used in safety assessment, In Vitro Toxicity Testing: explores whether existing test methods can accomplish the necessary goals and, if not, what research is needed to make these techniques a practical reality; presents the current status of toxicity testing in the areas of hepatotoxicity, renal toxicity, ocular irritation, and many others; outlines the role of validation in technology transfer from the research laboratory to safety evaluation; examines testing strategies and regulatory acceptance and addresses common concerns about the ultimate utilization of available methods in chemical safety/hazard considerations; and analyzes the perspective of industrial and regulatory agencies on the application of in vitro toxicity testing.;Generously referenced with over 1400 literature citations, In Vitro Toxicity Testing is for academic, industrial, and regulatory toxicologists; applied, molecular, and cell biologists; pharmacologists; animal welfare activists; and graduate students in pharmacology and toxicology courses.
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