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Chiral drugs, Lin, Guo-qiang You, Qi-dong Cheng, Jie-fei

Chiral drugs

Автор: Lin, Guo-qiang You, Qi-dong Cheng, Jie-fei
Название:  Chiral drugs   (Кустарные лекарственные препараты)
Издательство: Wiley
Классификация:
Промышленная химия

ISBN: 0470587202
ISBN-13(EAN): 9780470587201
ISBN: 0-470-58720-2
ISBN-13(EAN): 978-0-470-58720-1
Обложка/Формат: Hardback
Страницы: 472
Вес: 0.842 кг.
Дата издания: 26.08.2011
Язык: ENG
Иллюстрации: Illustrations
Размер: 244 x 166 x 29
Читательская аудитория: Professional & vocational
Подзаголовок: Chemistry and biological action
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: An integrated view of chiral drugs?—from concept and synthesisto pharmaceutical properties Chirality greatly influences a drugs biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and
Описание: Presenting an overview of chiral drugs and their impact on the pharmaceutical industry, Chiral Drugs: Chemistry and Biological Action provides an integrated perspective of chiral drugs from concept, synthesis, and pharmaceutical properties.
Дополнительное описание: ABOUT THE EDITORS vii CONTRIBUTORS ix INTRODUCTION 1 1 OVERVIEW OF CHIRALITY AND CHIRAL DRUGS 3 Guo-Qiang Lin, Jian-Ge Zhang, and Jie-Fei Cheng 2 CHIRAL DRUGS THROUGH ASYMMETRIC SYNTHESIS 29 Guo-Qiang Lin and Xing-Wen Sun 3 CHIRAL


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Handbook of Chiral Chemicals, Second Edition

Автор: David Ager
Название: Handbook of Chiral Chemicals, Second Edition
ISBN: 1574446649 ISBN-13(EAN): 9781574446647
Издательство: Taylor&Francis
Цена: 10120 р.
Наличие на складе: Поставка под заказ.
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Chiral Drugs

Автор: Cynthia A. Challener
Название: Chiral Drugs
ISBN: 0566084112 ISBN-13(EAN): 9780566084119
Издательство: Wiley
Цена: 17072 р.
Наличие на складе: Поставка под заказ.
Описание: In the early twentieth century the relevance of chirality to the pharmaceutical industry was established by the fact that one enantiomer of hyoscyamine possessed greater pharmacological activity than the other. Today, most new drugs and those under development consist of a single optically active isomer, and chirality is also becoming an issue for the agrochemical and other industries. Regulatory agencies throughout the world are currently reviewing the importance of chirality with regard to pharmaceutical and agrochemical products. New guidelines from such agencies have been key drivers for the focus on single enantiomer products in these industries. These scientific and regulatory developments have created the need for a guide for workers in the pharmaceutical and chemical industries seeking information on chiral molecules, processes, and commercially available chiral chemicals. "Chiral Drugs" is a comprehensive listing of over 2500 chiral drugs, classified by therapeutic class, and including structures and physical properties for each entry in the listing. Its companion volume, "Chiral Intermediates", presents the same detailed information for over 4700 commercially available chiral chemicals. The 'Chiral Pool' of readily available, relatively inexpensive chiral compounds has been expanding at a rapid rate as more and more products are produced in large quantities at ecomical prices. New developments in various technologies for isolating, preparing, and purifying chiral materials have greatly increased the opportunities for utilizing optically pure compounds in commercial applications. Novel techniques for classical resolution, new methodologies for developing selective enzymes for biocatalysis, advances in the application of microorganisms for chemical production, and continued progress in the area of asymmetric synthesis have all contributed to the growth of this field. Part One of each book contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds. Part Two presents entries for over 2500 chiral drugs, classified by therapeutic class. For each main entry, the chemical name and a list of trade names and synonyms is provided; the CAS Registry Number, the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number are given when available. The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended. "Chiral Drugs" provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for researchers in the pharmaceutical and biotechnology sectors as well as to those working in the basic biochemical sciences. "Chiral Intermediates" provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for information on available chiral molecules. "Chiral Intermediates" and "Chiral Drugs" are the most comprehensive and detailed guides to chiral compounds available.
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Chiral Intermediates

Автор: Cynthia A. Challener
Название: Chiral Intermediates
ISBN: 0566084120 ISBN-13(EAN): 9780566084126
Издательство: Wiley
Цена: 33264 р.
Наличие на складе: Поставка под заказ.
Описание: In the early twentieth century the relevance of chirality to the pharmaceutical industry was established by the fact that one enantiomer of hyoscyamine possessed greater pharmacological activity than the other. Today, most new drugs and those under development consist of a single optically active isomer, and chirality is also becoming an issue for the agrochemical and other industries. Regulatory agencies throughout the world are currently reviewing the importance of chirality with regard to pharmaceutical and agrochemical products. New guidelines from such agencies have been key drivers for the focus on single enantiomer products in these industries. These scientific and regulatory developments have created the need for a guide for workers in the pharmaceutical and chemical industries seeking information on chiral molecules, processes, and commercially available chiral chemicals. Chiral Intermediates presents the chemical professional with a comprehensive listing of over 4700 available chiral chemicals including specific data of interest for each entry in the listing. Its companion volume, Chiral Drugs presents the same detailed information for over 2000 chiral drugs. The 'Chiral Pool' of readily available, relatively inexpensive chiral compounds has been expanding at a rapid rate as more and more products are produced in large quantities at economical prices. New developments in various technologies for isolating, preparing, and purifying chiral materials have greatly increased the opportunities for utilizing optically pure compounds in commercial applications. Novel techniques for classical resolution, new methodologies for developing selective enzymes for biocatalysis, advances in the application of microorganisms for chemical production, and continued progress in the area of asymmetric synthesis have all contributed to the growth of this field. Part I contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds. Part II presents entries for 4700 commercially available chiral compounds. For each main entry, the chemical name and a list of trade names and synonyms is provided; the CAS Registry Number, the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number are given when available. The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended. Chiral Intermediates provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for information on available chiral molecules. Chiral Intermediates and Chiral Drugs are the most comprehensive and detailed guides to chiral compounds available.
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Chiral Catalyst Immobilization and Recycling

Автор: Dirk E. De Vos
Название: Chiral Catalyst Immobilization and Recycling
ISBN: 3527299521 ISBN-13(EAN): 9783527299522
Издательство: Wiley
Цена: 9680 р.
Наличие на складе: Поставка под заказ.
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Chiral separation methods for pharmaceutical and biotechnological products

Автор: Ahuja, Satinder
Название: Chiral separation methods for pharmaceutical and biotechnological products
ISBN: 0470406917 ISBN-13(EAN): 9780470406915
Издательство: Wiley
Цена: 11088 р.
Наличие на складе: Поставка под заказ.
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Chiral Environmental Pollutants / Trace Analysis and Ecotoxicology

Автор: Kallenborn R., HГјhnerfuss H.
Название: Chiral Environmental Pollutants / Trace Analysis and Ecotoxicology
ISBN: 3540664238 ISBN-13(EAN): 9783540664239
Издательство: Springer
Цена: 12316 р.
Наличие на складе: Есть у поставщика.Поставка под заказ.
Описание: The central topic of the book is to present the state of the art and future development of environmental enantioselective trace analysis. Areas such as toxicology, ecotoxicology, synthetic chemistry, biology, physics are also covered in detail in order to explain the different properties of enantiomers in environmental samples. This monograph delivers a comprehensive survey for environmental trace analysts, analytical chemists, ecotoxicologists, food scientists and experienced laboratory personnel.
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Chirality in Natural and Applied Science

Автор: Lough Wj, Brasier Martin, Wainer Iw, Olsen Y,
Название: Chirality in Natural and Applied Science
ISBN: 0632054352 ISBN-13(EAN): 9780632054350
Издательство: Wiley
Цена: 16368 р.
Наличие на складе: Поставка под заказ.
Описание: This text covers the applications of chirality in industry and beyond, and its natural occurrence on a variety of scales from the nano to the macro. The importance of this field has continued to grow with applications in the pharmaceutical, flavour and fragrance industries.
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