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Chiral drugs, Lin, Guo-qiang You, Qi-dong Cheng, Jie-fei

Chiral drugs

Автор: Lin, Guo-qiang You, Qi-dong Cheng, Jie-fei
Название:  Chiral drugs   (Кустарные лекарственные препараты)
Издательство: Wiley
Классификация:
Промышленная химия

ISBN: 0470587202
ISBN-13(EAN): 9780470587201
ISBN: 0-470-58720-2
ISBN-13(EAN): 978-0-470-58720-1
Обложка/Формат: Hardcover
Страницы: 472
Дата издания: 26.08.2011
Язык: ENG
Читательская аудитория: Professional & vocational
Рейтинг:
Поставляется из: Англии
Описание: An integrated view of chiral drugs?—from concept and synthesisto pharmaceutical properties Chirality greatly influences a drugs biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and
Дополнительное описание: ABOUT THE EDITORS vii CONTRIBUTORS ix INTRODUCTION 1 1 OVERVIEW OF CHIRALITY AND CHIRAL DRUGS 3 Guo-Qiang Lin, Jian-Ge Zhang, and Jie-Fei Cheng 2 CHIRAL DRUGS THROUGH ASYMMETRIC SYNTHESIS 29 Guo-Qiang Lin and Xing-Wen Sun 3 CHIRAL


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Handbook of Chiral Chemicals, Second Edition

Автор: David Ager
Название: Handbook of Chiral Chemicals, Second Edition
ISBN: 1574446649 ISBN-13(EAN): 9781574446647
Издательство: Taylor&Francis
Цена: 10120 р.
Наличие на складе: Нет в наличии.
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Chiral Intermediates

Автор: Cynthia A. Challener
Название: Chiral Intermediates
ISBN: 0566084120 ISBN-13(EAN): 9780566084126
Издательство: Wiley
Цена: 20856 р.
Наличие на складе: Поставка под заказ.
Описание: In the early twentieth century the relevance of chirality to the pharmaceutical industry was established by the fact that one enantiomer of hyoscyamine possessed greater pharmacological activity than the other. Today, most new drugs and those under development consist of a single optically active isomer, and chirality is also becoming an issue for the agrochemical and other industries. Regulatory agencies throughout the world are currently reviewing the importance of chirality with regard to pharmaceutical and agrochemical products. New guidelines from such agencies have been key drivers for the focus on single enantiomer products in these industries. These scientific and regulatory developments have created the need for a guide for workers in the pharmaceutical and chemical industries seeking information on chiral molecules, processes, and commercially available chiral chemicals. Chiral Intermediates presents the chemical professional with a comprehensive listing of over 4700 available chiral chemicals including specific data of interest for each entry in the listing. Its companion volume, Chiral Drugs presents the same detailed information for over 2000 chiral drugs. The 'Chiral Pool' of readily available, relatively inexpensive chiral compounds has been expanding at a rapid rate as more and more products are produced in large quantities at economical prices. New developments in various technologies for isolating, preparing, and purifying chiral materials have greatly increased the opportunities for utilizing optically pure compounds in commercial applications. Novel techniques for classical resolution, new methodologies for developing selective enzymes for biocatalysis, advances in the application of microorganisms for chemical production, and continued progress in the area of asymmetric synthesis have all contributed to the growth of this field. Part I contains four chapters which provide an introduction to topics relevant to the field of chiral chemistry and includes a brief overview of chirality, a short discussion on the current market drivers in the area of chiral chemistry, and a basic presentation of the various sources and methods for obtaining chiral compounds. Part II presents entries for 4700 commercially available chiral compounds. For each main entry, the chemical name and a list of trade names and synonyms is provided; the CAS Registry Number, the European Inventory of Existing Commercial Chemical Substances (EINECS) number, and the Merck Index (12th edition) number are given when available. The physical properties, including specific rotation, of each compound are described and indicated applications are presented. The structure of nearly every compound is provided, and the manufacturers and suppliers of the compounds are also given. Indexes, including a master index of names and synonyms and an index of custom manufacturing services for production of chiral compounds, are appended. Chiral Intermediates provides an introduction to the types of sources and methods currently in use for obtaining chiral molecules and is an invaluable resource for information on available chiral molecules. Chiral Intermediates and Chiral Drugs are the most comprehensive and detailed guides to chiral compounds available.
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Chiral Catalyst Immobilization and Recycling

Автор: Dirk E. De Vos
Название: Chiral Catalyst Immobilization and Recycling
ISBN: 3527299521 ISBN-13(EAN): 9783527299522
Издательство: Wiley
Цена: 9680 р.
Наличие на складе: Поставка под заказ.
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Recombinant Protein Drugs

Автор: Buckel P.
Название: Recombinant Protein Drugs
ISBN: 3764359048 ISBN-13(EAN): 9783764359041
Издательство: Birkhauser Verlag AG
Цена: 15147 р.
Наличие на складе: Нет в наличии.
Описание: Recombinant protein drugs are intimately associated with the impressive success story of the Biotech Industry during the past thirty years, some of them belonging to the most successful pharmaceutical products. More than thirty different proteins are available for a variety of clinical applications, over 300 proteins are presently being evaluated in clinical trials. In this new volume of the MDT series, historical, technical and clinical aspects of recombinant protein drug discovery and development are presented, covering past, present and future highlights. Leading scientists and co-founders of early Biotech companies describe technical breakthroughs and the fascinating story of pioneering discoveries, as well as the long way of translating them into products and business. Therefore, this book represents an exciting documentation of the beginning of a new era in the pharmaceutical industry. In addition, scientists from basic research, clinic and industry actively involved in new developments discuss...
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New Drugs for Asthma, Allergy and COPD

Автор: Hansel, T.T. (London); Barnes, P.J. (London);
Название: New Drugs for Asthma, Allergy and COPD
ISBN: 3805568622 ISBN-13(EAN): 9783805568623
Издательство: Karger
Цена: 19317 р.
Наличие на складе: Нет в наличии.
Описание: This book provides a state-of-the-art account by academic respiratory physicians and senior pharmaceutical industry personnel on the development of new drugs for asthma, allergy and COPD. It contains 80 chapters of highly condensed information, presented in an attractive, reader-friendly format with much use of tables, figures and diagrams. In addition to summarizing the diverse range of current approaches, this handbook also looks into the future, considering many topics that are promising, but have only emerged in the last few years.

Developments within established drug categories such as beta-2-agonists, steroids and leukotriene antagonists are also reviewed. Never before has a single book brought together so many pharmaceutical drug developers sharing their experience on such a wide range of respiratory topics!

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Chiral Environmental Pollutants / Trace Analysis and Ecotoxicology

Автор: Kallenborn R., HГјhnerfuss H.
Название: Chiral Environmental Pollutants / Trace Analysis and Ecotoxicology
ISBN: 3540664238 ISBN-13(EAN): 9783540664239
Издательство: Springer
Цена: 12317 р.
Наличие на складе: Нет в наличии.
Описание: The central topic of the book is to present the state of the art and future development of environmental enantioselective trace analysis. Areas such as toxicology, ecotoxicology, synthetic chemistry, biology, physics are also covered in detail in order to explain the different properties of enantiomers in environmental samples. This monograph delivers a comprehensive survey for environmental trace analysts, analytical chemists, ecotoxicologists, food scientists and experienced laboratory personnel.
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Chiral separation methods for pharmaceutical and biotechnological products

Автор: Ahuja, Satinder
Название: Chiral separation methods for pharmaceutical and biotechnological products
ISBN: 0470406917 ISBN-13(EAN): 9780470406915
Издательство: Wiley
Цена: 7920 р.
Наличие на складе: Поставка под заказ.
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Approaches to Design and Synthesis of Antiparasitic Drugs,

Автор: N. Anand
Название: Approaches to Design and Synthesis of Antiparasitic Drugs,
ISBN: 0444894764 ISBN-13(EAN): 9780444894762
Издательство: Elsevier Science
Цена: 17325 р.
Наличие на складе: Поставка под заказ.
Описание: Presents an account of the chemotherapy of parasitic diseases, human and veterinary. This book provides an overview of parasitic diseases. It is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. It deals with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and more.
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Targeted Delivery of Small and Macromolecular Drugs

Название: Targeted Delivery of Small and Macromolecular Drugs
ISBN: 142008772X ISBN-13(EAN): 9781420087727
Издательство: CRC Press
Цена: 5608 р.
Наличие на складе: Нет в наличии.
Описание: Site-specific drug delivery and targeting has attracted much research interest from both academia and industry, but because of the wide array of challenges faced in the development of these systems, only a very few targeted therapies have made it to clinics. Bringing together key research, this volume summarizes current progress with a focus on the novel ideas that are being explored to overcome these challenges. This forward-looking volume includes an in-depth review of various aspects of these drug delivery approaches as well as a detailed discussion of a few case studies in each category.
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Modern Drug Research: Paths To Better And Safer Drugs

Автор: Martin Yvonne C
Название: Modern Drug Research: Paths To Better And Safer Drugs
ISBN: 0824779029 ISBN-13(EAN): 9780824779023
Издательство: Informa
Цена: 13147 р.
Наличие на складе: Поставка под заказ.
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Handbook Of Pharmaceutical Manufacturing Formulations: Uncompressed Drugs Products

Автор: Niazi Sarfaraz K
Название: Handbook Of Pharmaceutical Manufacturing Formulations: Uncompressed Drugs Products
ISBN: 0849317479 ISBN-13(EAN): 9780849317477
Издательство: Informa
Цена: 17529 р.
Наличие на складе: Поставка под заказ.
Описание: The second volume in the six-volume Handbook of Pharmaceutical Manufacturing Formulations, this book covers uncompressed solids, which include formulations of powders, capsules, powders ready for reconstitution and other similar products from publicly available but widely dispersed information from FDA New Drug Applications (NDA), patent applications, and other sources of generic and proprietary formulations. Each entry begins with a fully validated scaleable manufacturing formula and a summary of manufacturing process. The book provides a detailed discussion on the difficulties encountered in formulating and manufacturing uncompressed drugs, the common elements of formulations.

The section on regulatory and manufacturing guidance deals with the topics of cGMP considerations in liquid manufacturing, stability testing of new drugs substances and products, container closure systems, pre-approval inspection, in addition to providing quick tips on resolving the common problems in formulating liquid drugs.

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Handbook Of Pharmaceutical Manufacturing Formulations: Over The Counter Drugs

Автор: Niazi Sarfaraz K
Название: Handbook Of Pharmaceutical Manufacturing Formulations: Over The Counter Drugs
ISBN: 0849317509 ISBN-13(EAN): 9780849317507
Издательство: Informa
Цена: 17529 р.
Наличие на складе: Поставка под заказ.
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