Multiple Sclerosis: Tissue Disease and Repair, Johnson
Автор: Cohen Название: Multiple Sclerosis Therapeutics ISBN: 0521766273 ISBN-13(EAN): 9780521766272 Издательство: Cambridge Academ Рейтинг: Цена: 25473 р. Наличие на складе: Есть (1 шт.) Описание: This book comprehensively reviews the current state of clinical trial methods in multiple sclerosis treatment, providing investigators, sponsors and specialists with current knowledge of outcome measures and study designs for disease and symptom management. The status of the rapidly evolving field of disease-modifying drugs is presented, with emphasis on the most promising therapies currently being tested. Experts discuss disease and symptom management for MS subtypes, including neuromyelitis optica and pediatric MS. In addition, key scientific advances in MS pathology, genetics, immunology and epidemiology are presented. The fourth edition has been extensively revised, featuring more than 50% new material. All chapters have been substantially updated to provide current information on rapidly evolving topics and this volume contains 15 new chapters, reflecting the growth of the field in recent years. This book is an essential reference for practitioners caring for MS patients, investigators planning or conducting clinical trials, and clinical trial sponsors.
Автор: Ruggieri Название: Multiple Sclerosis in Childhood ISBN: 3211989307 ISBN-13(EAN): 9783211989302 Издательство: Springer Рейтинг: Цена: 11544 р. Наличие на складе: Поставка под заказ.
Описание: Gives detailed presentations of the protean aspects of Multiple Sclerosis and its rare variants (example Balo`s, Devic`s, Marburg and Schilder`s disease), the clinically isolated syndromes, the acute and chronic parainfectious encephalomyelitides, the Central Nervous System vasculitides and other less common conditions.
Описание: Multiple Sclerosis and CNS Inflammatory Disorders is a practical guide to effective care of patients with multiple sclerosis and other neuroimmunologic and CNS inflammatory disorders. It provides the scientific basis of multiple sclerosis including etio
Автор: Stephen Waxman Название: Multiple Sclerosis As A Neuronal Disease, ISBN: 0127387617 ISBN-13(EAN): 9780127387611 Издательство: Elsevier Science Рейтинг: Цена: 23100 р. Наличие на складе: Поставка под заказ.
Описание: Examines the role of neurons in Multiple Sclerosis (MS) and the changes that occur in neurons as a result of MS. This book explains the basis for symptom production, remission and progress in MS. It brings together information from clinical, pathological, imaging, molecular, and pharmacological realms to explore the neurobiology of MS.
Автор: Finlayson Название: Multiple Sclerosis Rehabilitation ISBN: 1439828849 ISBN-13(EAN): 9781439828847 Издательство: Taylor&Francis Рейтинг: Цена: 24750 р. Наличие на складе: Поставка под заказ.
Описание: "MS is always in the back of your mind. If there is something you want to do, you always wonder if the MS will allow you do to it."—Darlene, living with MS for 22 years Living with multiple sclerosis (MS) is challenging and multidimensional. MS pervades all aspects of life: one’s body becomes unpredictable and unreliable, one’s identity and sense of self are tested, and relationships with others often change. MS symptoms emerge and remit; limitations evolve and progress. MS rehabilitation is an active, person-centered, and goal-oriented process embedded within a respectful and collaborative partnership between the person with MS and the members of his or her rehabilitation treatment team. Using the International Classification of Functioning, Disability and Health (ICF) as a guiding framework, Multiple Sclerosis Rehabilitation: From Impairment to Participation provides a comprehensive and evidence-based resource to inform and guide clinical reasoning and decision making during each phase of the MS rehabilitation process, from initial referral to post-discharge follow-up. With an emphasis on the application of evidence throughout the entire MS rehabilitation process, the specific objectives of the book are to increase the understanding of: The nature and impact of specific impairments, activity limitations, and participation restrictions experienced by people with MS How to select and use valid, reliable, and relevant assessment tools to inform the development of rehabilitation goals and intervention plans, and to evaluate outcomes This book provides information about the nature and impact of MS on the daily lives of people living with the disease, describes evidence-based assessment processes and instruments, and summarizes current knowledge that can inform goal setting and intervention planning. Thoughtful application of the knowledge contained in this book will inform and guide rehabilitation providers to work collaboratively with people with MS and enable them to achieve their goals for participation in everyday life.
Описание: Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis.Over the pastfive years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners.
Описание: This book explores and advances the concept that two neurological diseases, "mad cow disease" and multiple sclerosis, may be linked through exposure to the common microbe Acinetobacter, which is found in human sinuses, on skin and in the soil.
Описание: Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS). A number of research frontiers still exist in this challenging disease. The cause remains elusive, preventing breakthroughs in its prevention. The move towards oral immunomodulatory therapies has been a major advance, as has the finding of new genes linked to susceptibility that may open the door to new therapeutic approaches. However, a frontier that has been making significant strides in recent years has been that surrounding the neurobiology of myelin regeneration and axon protection: such have been the advances that clinical translation is on the cusp of being achieved. Two broad approaches to therapeutic enhancement of remyelination are envisaged: promoting endogenous remyelination by targeting cells present in the CNS, or, replacing lost myelinating cells from exogenous sources. Current research on oligodendrocyte biology, the pathology of MS, imaging of lesions and the biology of remyelination are paving the way toward opening this new translational frontier. Professor Duncan and Professor Franklin have assembled a broad group of experts in the fields of glial cell biology, neuropathology, radiology and clinical neurology to provide the background toward taking remyelination from experimented models into MS patients.
Описание: This reference presents cutting-edge basic and clinical research on all forms of interferon (IFN) involvement in the management of multiple sclerosis (MS)-detailing topics from IFN-receptor molecular interactions to synergy and interference with other agents such as cytotoxic drugs and chemotherapy. Features detailed research findings on IFN ? -1a (Avonex) and IFN -1b (Betaseron).
Описание: Controversy still exists regarding how early disease-modifying agents (DMA) should be commenced and whether all patients with relapsing-remitting MS should in fact be treated. With their novel, multifaceted approach to basic science, the authors of this book offer help to clinicians and hope to patients.
Автор: M. Filippi; M. Rovaris; G. Comi Название: Neurodegeneration in Multiple Sclerosis ISBN: 8847055830 ISBN-13(EAN): 9788847055834 Издательство: Springer Рейтинг: Цена: 19634 р. Наличие на складе: Поставка под заказ.
Описание: Written by world-renowned scientists, the volume provides a state-of-the-art on the most recent MRI techniques related to MS, and it is an indispensable tool for all those working in this field.
Название: Multiple Sclerosis ISBN: 0199603251 ISBN-13(EAN): 9780199603251 Издательство: Oxford Academ Рейтинг: Цена: 4244 р. Наличие на складе: Поставка под заказ.
Описание: Part of the Oxford Neurology Library series, this practical pocketbook will summarise the latest understanding of what might cause the disease, the methods of diagnosis and assessment, and current management techniques.
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