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ABC Proteins, Holland

Автор: Holland
Название:  ABC Proteins   (Белки АВС)
Издательство: Elsevier Science
Классификация:
Энциклопедии и справочные материалы
Прикладная физика и специальные разделы
Биохимия

ISBN: 0123525519
ISBN-13(EAN): 9780123525512
ISBN: 0-12-352551-9
ISBN-13(EAN): 978-0-12-352551-2
Обложка/Формат: Hardcover
Страницы: 672
Вес: 2.01 кг.
Дата издания: January 7, 2003
Ссылка на Издательство: Link
Поставляется из: Англии
Описание: ABC proteins (ATP-Binding Cassette proteins) transport a variety of molecules across membranes. They comprise one of the largest protein families known - 56 members have been identified in humans alone. Different ABC proteins transport a remarkably varied range of vital molecules across membranes, from small molecules such as chloride ions through to large molecules such as cholesterol, anti-cancer drugs and bacterial toxins. Many mammalian ABC are of considerable medical importance and are implicated in genetic diseases such as heart disease, cystic fibrosis, Stargardts retinal dystrophy and adrenoleukodystrophy. Others are involved in the immune system, lung function, the arterial system, digestive system, kidney and liver function, apoptosis, retinal function, clinical multiple drug resistance, tumour cell growth and in infectious agents. The same family of proteins is also found in bacteria, fungi, insects, plants and mammals. In bacteria, ABC transporters are not only required for nutrient uptake, but are implicated in toxin and protease secretion, as well as multiple antibiotic resistance. The family is one of the fastest growing protein groups, and research - especially given the medical importance of these proteins - is increasing at an exponential rate. For instance, the number of NIH grants concerning ABC Proteins has risen 11-fold in the last 10 years. The pace is accelerating, and is expected to continue. This title forms an in depth analysis of all we know about ABC Proteins to date.
Дополнительное описание: Кол-во стр.: 672
Формат: 270 x 200
Дата издания: 2002
Страна: UK
Круг читателей: academic, specialist
Иллюстрации: Colour illustrations
Вес: 2010



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How proteins work

Автор: Williamson, Mike
Название: How proteins work
ISBN: 0815344465 ISBN-13(EAN): 9780815344469
Издательство: Taylor&Francis
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Цена: 4769 р.
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Crystallization of Nucleic Acids and Proteins: A Practical Approach

Название: Crystallization of Nucleic Acids and Proteins: A Practical Approach
ISBN: 0199636788 ISBN-13(EAN): 9780199636785
Издательство: Oxford Academ
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Цена: 7916 р.
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Описание: Crystallography is the major method of determining structures of biological macromolecules yet crystallization techniques are still regarded as difficult to perform. This new edition of Crystallization of Nucliec Acids and Proteins: A Practical Approach continues in the vein of the first edition by providing a detailed and rational guide to producing crystals oroteins and nucleic acids of sufficient quantity and quality for diffraction studies. It has been thoroughly updated to include all the major new techniques such as the uses of molecular biology in structural biology (maximizing expression systems, sequence modifications to enable crystallization, and the introduction of anomalous scatterers); diagnostic analysis of prenucleation and nucleation by spectroscopic methods; and the two- dimensional electron crystallography of soluble proteins on planar lipid films. As well as an introduction to crystallogenesis, the other topics covered are: Handling macromolecular solutions, experimental design, seeding, proceeding from solutions to crystals Crystallization in gels Crystallization of nucleic acid complexes and membrane proteins Soaking techniques Preliminary characterization As with all Practical Approach books the protocols have been written by experienced researchers and are tried an tested methods. The underlying theory is brought together with the laboratory protocols to provide researchers with the conceptual and methodological tools necessary to exploit these powerful techniques. Crystallization of Nucliec Acids and Proteins: A Practical Approach 2e will be an invaluable manual of practical crystallization methods to researchers in molecular biology, crystallography, protein engineering, and biological chemistry.

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Cellular Lipid Binding Proteins

Автор: Glatz Jan F.C.
Название: Cellular Lipid Binding Proteins
ISBN: 1402072201 ISBN-13(EAN): 9781402072208
Издательство: Springer
Цена: 16962 р.
Наличие на складе: Поставка под заказ.

Описание: It is well established that cellular lipid binding proteins serve central roles in cellular lipid uptake and metabolism. Evidence has been presented that various metabolic diseases, such as hyperlipidemia, atherosclerosis, insulin resistance, and diabetes, are characterized by malfunctioning or deficiencies in cellular lipid binding proteins. For better understanding of the action of lipids as signaling compounds and the role of lipids in intermediary metabolism, it is essential to have detailed knowledge of the interactions between lipids and their cognant binding proteins. In view of this growing interest in lipid-protein interaction, the 4th International Conference on Lipid Binding Proteins was held in Maastricht, The Netherlands, in June 2001. The proceedings of the previous three meetings have been published in Molecular and Cellular Biochemistry. The present focused issue of Molecular and Cellular Biochemistry comprises selected papers based on the lectures and posters presented during the 4th conference, and provides insight into the significance of these proteins for the functioning of the cell.

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PAS Proteins: Regulators and Sensors of Development and Physiology

Автор: Crews Stephen T.
Название: PAS Proteins: Regulators and Sensors of Development and Physiology
ISBN: 1402075863 ISBN-13(EAN): 9781402075865
Издательство: Springer
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Цена: 11962 р.
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Описание: The subject of this volume is a comprehensive examination of the biochemistry and biology of all classes of known PAS proteins, with the intention that readers will find insight into their own work and ideas from study of the multitude of PAS protein functions. PAS proteins control numerous physiological and developmental events, and span phylogeny from bacteria to man. Bacterial and plant PAS proteins act as sensors of environmental stimuli, including light, oxygen, and energy status.PAS proteins encompass many fields of biology, and scientists who work in these fields (circadian rhythms, oxygen regulation, toxin metabolism, bacterial sensors, and development) are an audience, particularly those who actively work on PAS proteins and researchers interested in transcriptional control, signal transduction, and evolution.

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Capillary Electrophoresis of Proteins and Peptides

Автор: Strege Mark A., Lagu Avinash L.
Название: Capillary Electrophoresis of Proteins and Peptides
ISBN: 1588290174 ISBN-13(EAN): 9781588290175
Издательство: Springer
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Цена: 15262 р.
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Описание: Expert academic and pharmaceutical researchers describe their best capillary electrophoresis techniques for protein and peptide analysis. The authors present cutting-edge techniques for both capillary coatings and analytic detection via laser-induced fluorescence, for the development and commercialization of biopharmaceuticals, and for affinity capillary electrophoresis in the evaluation of protein binding, including the use of protein charge ladders. Areas of special interest covered include combining CE and capillary isoelectric focusing with electrospray mass spectrometry detection to perform proteomic studies and applications in the field of protein-ligand binding.

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G Proteins, Receptors, and Disease

Автор: Spiegel Allen M.
Название: G Proteins, Receptors, and Disease
ISBN: 0896034305 ISBN-13(EAN): 9780896034303
Издательство: Springer
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Цена: 18893 р.
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Описание: This collection of cutting-edge chapters summarizes in depth the state of our knowledge today concerning how cells communicate via G protein-coupled signal transduction and how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function of a particular G protein or receptor, lists possible mutations, and discusses fully the molecular pathogenesis of associated diseases. Full advantage is taken of insights from artificially created disorders using transgenic and gene knockout approaches. Diagnostic and therapeutic implications are also discussed where relevant. In its unique blend of basic science and clinical medicine, G Proteins, Receptors, and Disease offers deep insights into the physiological significance of this key signal transduction pathway and into the molecular basis of diseases ranging from obesity to malignancy.

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Mass Spectrometry of Proteins and Peptides

Автор: Chapman John R.
Название: Mass Spectrometry of Proteins and Peptides
ISBN: 089603609X ISBN-13(EAN): 9780896036093
Издательство: Springer
Цена: 9071 р.
Наличие на складе: Поставка под заказ.

Описание: John R. Chapman recreates the success of his earlier acclaimed book (Protein and Peptide Analysis by Mass Spectrometry, 1996) with a major new collection of cutting-edge methods in the analysis of proteins and peptides. Contributed by well-established investigators, each chapter provides background information before guiding the researcher step-by-step through the experimental process, with detailed instructions to help assure experimental success. The applications covered range widely and include protein sequencing, higher-order structure determination, epitope mapping, kinetics, quantitation, glycosylation analysis, and bacterial typing. Authoritative and eminently practical, Mass Spectrometry of Proteins and Peptides demonstrates the full scope of this versatile analytical technique. All protein chemists and biochemists, as well as bioanalytical scientists, who want to exploit these powerful methods in their work, will find this book indispensable.

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Molecular Modeling of Proteins

Автор: Kukol Andreas
Название: Molecular Modeling of Proteins
ISBN: 1588298647 ISBN-13(EAN): 9781588298645
Издательство: Springer
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Цена: 10724 р.
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Описание: offers introductions and methods applicable to problems faced by non-specialists - especially those new to the software packages used in molecular modeling. This book provides tips on troubleshooting and avoiding common pitfalls, along with chapters covering a range of subjects ranging from free energy calculation to applications for drug design.

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Cell Death Proteins,53

Автор: Gerald Litwack
Название: Cell Death Proteins,53
ISBN: 0127098534 ISBN-13(EAN): 9780127098531
Издательство: Elsevier Science
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Цена: 14025 р.
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Описание: This volume studies cell death, and includes new discoveries concerning proteins that are produced by dying cells as well as the proteins that signal cells to iniate cell death.

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Bioseparations of Proteins,1

Автор: Ajit Sadana
Название: Bioseparations of Proteins,1
ISBN: 0126140405 ISBN-13(EAN): 9780126140408
Издательство: Elsevier Science
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Описание: Covers the fundamentals of protein inactivation during bioseparation and the effect on protein processing. This book provides a background of the bioseparation processes, and emphasizes the influence of the different bioseparation processes on protein inactivation. It includes case studies from the literature on separation processes and economics.

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Electrochemistry of Nucleic Acids and Proteins,1

Автор: E. Palecek
Название: Electrochemistry of Nucleic Acids and Proteins,1
ISBN: 044452150X ISBN-13(EAN): 9780444521507
Издательство: Elsevier Science
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Цена: 29288 р.
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Описание: DNA (sometimes referred to as the molecule of life), is the most interesting and most important of all molecules. This book deals with the electrochemistry of DNA and RNA and to the development of sensors for detecting DNA damage and DNA hybridization. It covers the methods of electrochemical analysis of nucleic acids and proteins.

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Proteins, Peptides, and Amino Acids SourceBook

Автор: White John Stephen, White Dorothy Chong
Название: Proteins, Peptides, and Amino Acids SourceBook
ISBN: 0896036138 ISBN-13(EAN): 9780896036130
Издательство: Springer
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Цена: 21588 р.
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Описание: Building on the success of their Source Book of Enzymes, John and Dorothy Chong White have assembled an exhaustive catalog of over 26,000 commercially available proteins, peptides, and amino acids, all arranged alphabetically and by sequence for fast access, and each replete with technical details and vendor information. Compounds can be easily located by either directly searching the appropriate section by chemical name, or by consulting the general index by name, synonym, or derivative formula. Peptides with known sequences may be found alphabetically by basic sequence (no modification) or by consulting the Sequences Index. A Glossary of Abbreviations and Acronyms makes it possible to quickly find compounds by their common names. Once the desired compound is located, the selection of the right product for an application is facilitated by presenting its specific technical data in an easy-to-use format that permits comparison across sources. This valuable data covers sequence, sequence modification, chemical derivatives, preparation form, purity, composition, activity, functionality, temperature/pH optima, as well as product notes that list known applications, compound importance, and literature references. The selected compound may then be ordered by using the catalog number provided and the Reagent Suppliers Index.

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