Автор: De Ley Название: Cytokine Protocols ISBN: 1617794384 ISBN-13(EAN): 9781617794384 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: “Recent studies have discovered new known and characterized cytokines, allowing for advancement in miniaturization of micro-analytical methods as well as the extensive development of bio-informatics and nanotechnology. These advancements have allowed researchers to reduces sample sizes making for more accurate determinations then previously possible. In Cytokine Protocols: Second Edition, expert researchers in the field detail many of the methods which are now commonly used to study cytokines. These methods and techniques for studying cytokines include historical importance and the importance of researchers using bioassay, quantification, and characterization of cytokine related RNAs, posttranscriptional modifications of RNA, either naturally or artificially, and observations at the protein level. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Cytokine Protocols: Second Edition seeks to aid scientists in furthering the crucially important advancement of cytokine research.”
Автор: Balkwill Название: Cytokine Molecular Biology ISBN: 0199638594 ISBN-13(EAN): 9780199638598 Издательство: Oxford Academ Рейтинг: Цена: 13464.00 р. Наличие на складе: Поставка под заказ.
Описание: This work examines techniques for studying cytokines, cytokine receptors, and cytokine driven processes. Assays for human B-cell responses, leucocyte migration, haematopoietic growth factors, macrophage activation by cytokine and quantitative biological assays for cytokines are covered.
Автор: Katherine A. Fitzgerald Название: The Cytokine Factsbook and Webfacts, ISBN: 0121551423 ISBN-13(EAN): 9780121551421 Издательство: Elsevier Science Рейтинг: Цена: 18275.00 р. Наличие на складе: Поставка под заказ.
Описание: This is a reference manual for all current well-characterised interleukins, cytokines and their receptors. Introductory chapters provide background information on the cytokine network and cytokine receptor superfamilies. This is followed by over 100 comprehensive individual entries covering each characterised cytokine/chemokine/growth factor. Information is also provided on cytokine standards and protein sequence retrieval database servers. The manual also includes free online access to Cytokine Webfacts, which provides online access to a comprehensive compendium of facts about cytokines and their receptors. This compendium includes a variety of data representations, such as text information, signal pathway diagrams and 3D images.
Описание: This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.
Автор: Mantovani Название: Pharmacology of Cytokines.2000 ISBN: 0198500424 ISBN-13(EAN): 9780198500421 Издательство: Oxford Academ Рейтинг: Цена: 22176.00 р. Наличие на складе: Поставка под заказ.
Описание: Cytokines are polypeptide mediators which act as communication signals among cells of the immune system as well as among other cells and tissues in the body. They are a heterogeneous and complex group and include interferons, tumor necrosis factor and chemokines. They play a key role in homeostasis and in host defence and are involved in such inflammatory and autoimmune diseases such as rheumatoid arthritis as well as infectious diseases such as HIV infection and septic shock. Modulation of the production and action of cytokines, as well as their exploitation as therapeutic agents, has been the object of intense and competitive research. The pharmacology of cytokines is an exploding area which is entering the clinical arena. This book gives an overview of cytokine research and describes the various approaches that have been taken to develop the pharmacology of these novel mediators. Within the framework of the immunobiology of cytokines, the book examines the interactions with the cytokine system of a variety of compounds ranging from simple synthetic chemicals to biotechnological products . In addition to examining individual agents and approaches, it reviews the pathophysiology o
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