Описание: A TASER Conducted Electrical Weapons is a hand-held device that delivers a 400-volt pulse with a duration tuned to control the skeletal muscles without affecting the heart at a distance of up to 6.5 meters over tiny wires. This title deals with this device and is of interest to cardiologists, emergency physicians, and pathologists.
Описание: Provides an analysis of the conduct of clinical investigation in patients with acute decompensated heart failure (ADHF). This title tackles the difficult questions involved in patient population, trial conduct, surrogate endpoints, clinical endpoints, and statistical considerations.
Автор: Kirby, Margaret Loewy Название: Cardiac Development ISBN: 019517819X ISBN-13(EAN): 9780195178197 Издательство: Oxford Academ Рейтинг: Цена: 17256 р. Наличие на складе: Невозможна поставка.
Описание: This new book is the only in-depth, single-author reference on heart development. Clearly written, with lavish colour illustrations, it provides a more clinical, systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classic anatomic studies to recent findings in molecular biology. Author Margaret Kirby posits a unifying understanding of heart tube formation from the cardiogenic fields, and the book covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, conduction system development, evolutionary developmental biology of the heart, and myocardial stem cells. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.
Описание: Basic and clinical researchers from industry and academia detail the preclinical, clinical, and regulatory principles currently used to assess the cardiac safety of new drugs. The authors explain the parameters of cardiac safety at all stages of clinical research and drug development, including both the preclinical and pharmacogenomic aspects generally and the clinical methodologies and technical aspects for investigational drugs based on cardiac repolarization, as defined by the duration of the QTc interval. Additional chapters comprehensively review the application of electrocardiography in clinical research, the fundamentals of ECG interpretation in clinical trials, the statistical analysis plans for ECG data obtained in formal clinical trials, and the practical interpretation of the ECG results. Highlights include practical guidance on how to conduct a thorough ECG Trial in New Drug Development, how to use new ECG and web based technology in clinical research, and how to follow the new FDA requirements for ECG submissions.
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