Автор: Ainscough Название: Nuclear Reprogramming and Stem Cells ISBN: 1617792241 ISBN-13(EAN): 9781617792243 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states. Importantly, in addition to offering the opportunity to delve deeply into the mechanisms that drive disease aetiology the research is realistically opening the doors for development of targeted and personalized therapeutic applications that many considered, until recently, to be nothing more that a far fetched dream. This volume provides a timely glimpse into the methods that have been developed to instigate, and the mechanisms that have been identified to drive, the process of nuclear reprogramming, chronicling how the field has developed over the last 50-60 years. Since the early 1950s a small number of notable experiments have provided significant impetus to the field, primarily the demonstration of reprogramming ability, first by the complex cytoplasmic milieu that constitutes the amphibian egg, then that of the mammalian egg, and finally that of the mammalian embryonic stem cell. Most recently, the demonstration that a limited pool of defined molecules is capable of reprogramming a multitude of cell types has provided massive impetus and facilitated transition towards realistic therapeutic application. We have therefore reproduced some of the key articles that elegantly document these dramatic stages of development of the field in an inclusive appendix to the book, for the benefit of readers keen to investigate the history of how the field of stem cell biology has evolved. Owing to the ever broadening nature of this field, and the incredible rate at which it is evolving, the main content of this volume focuses on areas that have shown significant movement in recent years, are most likely to translate into personalized therapeutic application, and thus provide greatest potential for significant impact on human health in the not too distant future. We recognize that research into many other disease states and cell types are all equally worthy of discussion. We would therefore like to acknowledge those researchers involved whose work we have not been able to include in this volume. Nuclear Reprogramming and Stem Cells will serve as a valuable resource for all researchers in the field of stem cell biology, including those just setting out on their career path as well as those already established in the field.
Автор: Zhang Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 1607617684 ISBN-13(EAN): 9781607617686 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This cutting-edge text will be a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and exciting areas of research such as regenerative medicine and cancer.
Автор: Yaoliang Tang Название: Genetics of Stem Cells,111 ISBN: 0123984599 ISBN-13(EAN): 9780123984593 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Поставка под заказ.
Описание: Focuses on the genetics of stem cells.
Автор: Goldenberg Название: Resident Stem Cells and Regenerative Therapy, ISBN: 0124160123 ISBN-13(EAN): 9780124160125 Издательство: Elsevier Science Рейтинг: Цена: 21054.00 р. Наличие на складе: Поставка под заказ.
Описание: Stem cells have greatly impacted the scientific and lay communities, providing advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, cystic fibrosis, cirrhosis, and osteoporosis. This title presents the important factors to be considered when considering resident stem cells in regenerative therapies.
Автор: Quigley Muireann Название: Stem Cells: New Frontiers in Science & Ethics ISBN: 9814374245 ISBN-13(EAN): 9789814374248 Издательство: World Scientific Publishing Рейтинг: Цена: 15048.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Deals with various aspects of the stem cell debate, from the ethical challenges of conducting stem cell research to those of the clinical application of stem cell technology. This title brings fresh perspectives on the permissibility of using embryos in stem cell research.
Автор: Charles J. Malemud; Eben Alsberg Название: Mesenchymal Stem Cells and Immunomodulation ISBN: 331946731X ISBN-13(EAN): 9783319467313 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This essential volume explores mesenchymal stem cells (MSCs) and their potential to suppress immune-mediated inflammation. The chapters examine applications in autoimmune diseases such as lupus, rheumatoid arthritis and multiple sclerosis; blood cancers such as leukemia and lymphoma; and reproductive complications, specifically pre-term labor and use of MSCs in vitro and in animal models to discover methods of suppressing the causal inflammatory response. It also further defines the methodologies required to develop research on MSCs in vitro into established preclinical animal models including those which are proven replicas of autoimmunity and pre-term labor, to name but two.
Mesenchymal Stem Cells and Immunomodulation, part of Springer’s Stem Cell Biology and Regenerative Medicine, is an invaluable resource for researchers and clinicians working with stem cells, autoimmune disease, oncology, and reproductive medicine.
Автор: ?ahin Название: Dental Stem Cells ISBN: 3319289454 ISBN-13(EAN): 9783319289458 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book explores Dental Stem Cell (DSC) biology, from a review of basic concepts for cell culture, to isolation, self-renewal, multipotency and differentiation, regulation by molecular medicine, and prospective research areas for regenerative medicine. The first seven chapters delve into basic DSC properties, vital signaling pathways involved in differentiation, pluripotency, iPS cell development from DSCs, and genetic engineering approaches of DSCs in accordance with the current literature. A comprehensive review of possible clinical applications and in vitro/in vivo studies follows, illustrating the future of DSC research for in the tissue engineering field. The text also discusses the political, ethical, social, and legal ramifications of the use of dental stem cells.
Expertly authored and drawing from a multitude of international perspectives, Dental Stem Cells is an invaluable addition to Springer’s Stem Cell Biology and Regenerative Medicine series. It is essential reading for advanced graduate students, basic researchers, and clinical investigators in the fields of stem cell therapy, biological sciences of dentistry, and regenerative medicine.
Автор: Sell Название: Stem Cells Handbook.2003 ISBN: 1588291138 ISBN-13(EAN): 9781588291134 Издательство: Springer Цена: 20257.00 р. Наличие на складе: Поставка под заказ.
Описание: This survey on the "state-of-the-science" of stem cell biology explains the origins of stem cells and describes how they function, how they can cause illness, and how they might be employed to cure or ameliorate disease. In particular, the authors discuss the roles of stem cells in development and organogenesis, in normal tissue turnover, in the repair response to injury, and in carcinogenesis. They also explain how to obtain stem cells from different organs, culture them in vitro, and manipulate them for therapeutic use.
Автор: Morser Название: Stem Cells in Reproduction and in the Brain. 2006 ISBN: 3540314369 ISBN-13(EAN): 9783540314363 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: What Lessons can Regenerative Medicine Learn From Developmental Biology?- What is a Stem Cell Niche?- New Strategy for Comprehensive Analysis of Gene Functions in ES Cells.-Paternal Dual Barrier by Ifg2-H9 and Dlk1-Gtl2 to parthenogenesis in Mice?- Cell-Cell Fusion as a Means to Establish Pluripotency.- Towards Reprogramming Cells to Pluripotency.- Molecular Switches and Developmental Potential of Adult Stem Cells.- Adult Small Intestinal Stem Cells. Identification, Location, Characteristics and Clinical Applications. Tracking Stem Cells in vivo. Establishment of Nuclear Transfer Embryonic Stem Cell Lines From Adult Somatic Cells by Nuclear Transfer and its Application.- Derivation of Germ Cells From Embryonic Stem Cells.-Germline Recruitment in Mice: A Genetic Program for Epigenetic Reprogramming.- Transplantation of Germ Line Stem Cells for the Study and Manipulation of Spermatogenesis.- Progenitor Cell-Based Myelination as a Model for Cell-Based Therapy of the CNS.- Adult Neural Stem Cells and CNS Repair.- Stem Cell Therapy for Parkinson’s Disease
Автор: Ulrich Название: Working with Stem Cells ISBN: 3319305808 ISBN-13(EAN): 9783319305806 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The content covered encompass not only the theoretic and methodological aspects for culturing human pluripotent stem cells, but also the establishment of induced pluripotent stem cells and their differentiation into specific cellular subtypes. This book has the most updated methods and technologies in an accessible and clear language, presenting protocols developed and optimized by researchers that use them every day. Stem cell research is a growing field that offers the potential to comprehend mechanisms of neural development and tissue regeneration and maintenance as well as the development-related human diseases and the establishment of novel therapies. Questions of basic biology can also be exploited by this cutting-edge approach.
Автор: Zavan Название: Dental Stem Cells: Regenerative Potential ISBN: 331933297X ISBN-13(EAN): 9783319332970 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology.
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