Описание: This important reference offers a comprehensive review of the graft-versus-leukemia (GVL) or -tumor (GVT) effect following allogeneic stem cell transplantation and lymphocyte transfusion, covering a wide range of topics from alloimmune responses to clinical applications of GVL, and providing the basics to understand the mechanisms of the GVL effect while demonstrating methods that use the GVL effect to cure a greater number of cancer patients. Presents preliminary data supporting the idea that allogeneic cell therapy can be used not only for the treatment of leukemia but also for metastatic solid tumors! Written by over 40 world renowned experts in the field and containing more than 1450 references for in-depth exploration of the subject, Allogeneic Immunotherapy for Malignant Diseases
investigates the capacity of the donor-and the host-to destroy residual leukemia cells by allogeneic immune reaction
determines how to direct immune reactions against hematopoietic malignancies safely
reveals which other malignant conditions may be responsive to allogeneic-mediated graft-versus-tumor reactions
covers the mechanisms that contribute to the development of responses to minor histocompatibility complex (mHC) molecules
focuses on the biology of effector cells and their role in mediating GVL reactions in chronic myeloid leukemia (CML)
summarizes the putative impact of human mHag on the GVL effect in bone marrow transplantation (BMT)
addresses the potential and limitations of oncogene-based immunotherapy
examines ways to isolate and control the GVL component of allograft immunity
discusses efforts to develop specific anti-leukemic T-cell immunotherapy
and more! Attributing the curative effect of allogeneic stem cell transplantation to the GVL or GVT effect, Allogeneic Immunotherapy for Malignant Diseases is an indispensable reference for hemat
Описание: Lung cancer is the neoplastic disease with the highest mortality numbers in the world. The disease is very common in industrialized countries. This textbook synthesizes the basic science of lung cancer with state-of-the-art accounts of diagnosis and treatment. Written by a distinguished panel of experts from Europe, Asia, and North America, it covers all of the most important fields: biology, pathology, epidemiology, screening, diagnosis, therapy, supportive care, and prognosis. All physicians caring for patients with lung cancer, especially surgeons, chest physicians, radiation oncologists, and medical oncologists, will find a wealth of information that meets their needs. Whenever possible, the principles of evidence-based medicine are followed by providing data from systematic reviews, meta-analyses, methodology-based guidelines, and randomized clinical trials.
Автор: Saba Название: Advances in Malignant Hematology ISBN: 1405196262 ISBN-13(EAN): 9781405196260 Издательство: Wiley Рейтинг: Цена: 13340 р. Наличие на складе: Нет в наличии.
Описание: Advances in Malignant Hematology captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current o
Автор: Degos Название: Textbook Of Malignant Haematology ISBN: 1853173223 ISBN-13(EAN): 9781853173226 Издательство: Informa Рейтинг: Цена: 14955 р. Наличие на складе: Нет в наличии.
Описание: This textbook provides a concise overview of malignant haematology, including reviews of cell and molecular biology, and implications for new trends in treatment.
Описание: The TNM system is the most widely used means for classifying the extent of cancer spread. "TNM Classification of Malignant Tumours, Sixth Edition" provides the new, internationally agreed-upon standards to describe and categorize cancer stages and progression. Published in affiliation with the International Union Against Cancer (UICC), this pocket guide contains important new and updated organ-specific classifications that oncologists and other professionals who treat patients with cancer must use (starting with cases diagnosed and treated in 2003) to adequately classify tumours for prognosis and treatment. Revised standards include: major alterations in the classifications concerning carcinomas of the liver, biliary tract and pancreas, pleural mesothelioma, bone tumours, malignant melanoma of the skin, ophthalmic tumours, and the regional lymph node classification of breast carcinoma; a nasal cavity tumour classification; changes in classification of head and neck tumours; risk factors for gestational trophoblastic tumours have been modified according to FIGO recommendations; new subcategories in gastric, prostate, and kidney tumour classifications and in the stage grouping of colorectal carcinoma; and schemes for recording the assessment of sentinel lymph nodes and isolated tumour cells. The definition of the 'y' symbol for cases classified during or after initial multimodality therapy has been further clarified. These changes will enhance the value of TNM in treatment planning and as a prognostic indicator.
Автор: Buchan John, Lopes Tito, Roberts Dafydd, Naik Raj, Название: Pocket Guide to Malignant Melanoma ISBN: 0632054212 ISBN-13(EAN): 9780632054213 Издательство: Wiley Рейтинг: Цена: 2309 р. Наличие на складе: Нет в наличии.
Описание: This pocket guide can be used as a background reference to help healthcare professionals become familiar with the appearance of melanoma and its differential diagnosis; and as a just-in-time resource to provide advice on borderline cases, or help in interpreting a pathology report.
Автор: Jain S. Lochlann, Jain Sarah S. Lochlann Название: Malignant: How Cancer Becomes Us ISBN: 0520276574 ISBN-13(EAN): 9780520276574 Издательство: Wiley Рейтинг: Цена: 2888 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer can kill: this fact makes it concrete. Still, it`s a devious knave. Nearly every American will experience it up-close and all too personally, wondering why the billions of research dollars thrown at the word haven`t exterminated it from the English language. This title deals with this cancer.
Автор: G J Mufti Название: Malignant Haematology ISBN: 1853170542 ISBN-13(EAN): 9781853170546 Издательство: Informa Рейтинг: Цена: 17256 р. Наличие на складе: Нет в наличии.
Описание: A collection of images which constitute a detailed pathological coverage of the haematological malignancies. The text includes a review of all aspects of the various disorders, including morpological abnormalities, FAB classification, and cytochemical and immunocytochemical characteristics.
Автор: Barnhill Raymond L., Trotter M.J. Название: Pathology of Malignant Melanoma ISBN: 0387207104 ISBN-13(EAN): 9780387207100 Издательство: Springer Рейтинг: Цена: 12539 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An excerpt from "Pathology of Melanocytic Nevi and Malignant Melanoma, Second Edition", Pathology of Malignant Melanoma provides a highly practical approach to the histopathological diagnosis of melanoma of the skin. Emphasis is placed on the differential diagnosis of major forms of conventional melanoma, and the book also discusses unusual or rare variants that are difficult to recognize. This portable, user-friendly handbook addresses epidemiology, criteria for diagnosis and classification of melanoma, risk factors, and other morphological and cytological variants. More than 30 easy-to-read tables provide at-a-glance reference and over 100 full color illustrations complement the text.
Автор: Galateau-Sall? Название: Pathology of Malignant Mesothelioma ISBN: 1849969396 ISBN-13(EAN): 9781849969390 Издательство: Springer Рейтинг: Цена: 19854 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Mesothelioma is a global problem, its incidence is rising in Europe, and it is a major health problem in the USA and other parts of the world, largely related to the previous use of asbestos products. Diagnosis, which rests on the pathology, is very difficult because of its diverse appearances and the potential for other diseases to mimic it.
This monograph has been assembled by an international group of experts with a wealth of experience from France, UK, USA, Australia and Canada to aid in pathological diagnosis. In all these countries, the disease poses significant health problems. This book deals with clinical, radiological, epidemiological, molecular, and histopathological aspects of the disease. Tumors of the pleural, pericardial, peritoneal cavities as well as the ovary and tunica vaginalis are considered. Differential diagnoses of serosal-based lesions are fully discussed and the use of immunohistochemical stains is explained. Plentiful illustrations give further aid to diagnosis
An essential read for all diagnostic pathologists as well as general pathologists, who are sometimes required to diagnose the disease at biopsy or post mortem. The book will be also invaluable to members of the medical and legal professions who are involved with various aspects of this disease.
Автор: Tannapfel Название: Malignant Mesothelioma ISBN: 364210861X ISBN-13(EAN): 9783642108617 Издательство: Springer Рейтинг: Цена: 20900 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Malignant mesothelioma is an aggressive and fatal neoplasm of serous membranes that still shows a rising incidence worldwide. This book covers all the important aspects of the disease by bringing together contributions from selected experts in the fields of epidemiology, imaging, pathological diagnosis, therapy, genetics, and screening. Special emphasis is placed on the latest diagnostic techniques and current therapy standards. In addition, the mineralogy of asbestos is reviewed and clear advice is included on the analysis of tissue mineral fiber content. By providing a compact, scientifically based, and up-to-date overview of the management of malignant mesothelioma, this volume will be invaluable for all clinicians and pathologists who are engaged in the diagnosis and treatment of the disease or in related research.
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