Gene and Genome Technology, Primrose B Sandy, Herod Andrew, Twyman Richard, Br
Автор: T. Brown Название: Genomes 4 ISBN: 0815345089 ISBN-13(EAN): 9780815345084 Издательство: Taylor&Francis Рейтинг: Цена: 9645.00 р. Наличие на складе: Поставка под заказ.
Описание:
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.
Автор: Dennis Название: The Human Genome.2001 ISBN: 0333971434 ISBN-13(EAN): 9780333971437 Издательство: Palgrave Рейтинг: Цена: 3538.00 р. Наличие на складе: Нет в наличии.
Описание: The sequencing of the human genome has been hailed as the most ground breaking scientific event of the new century. It offers the exciting prospect of fresh insights into our collective history, our shared identity and our individuality, and opens up important possibilities for the identification, treatment and prevention of disease. Not since Crick and Watson's seminal paper on the structure of DNA has a scientific publication been greeted with so much public expectation for a new understanding of the basis of life itself. In this illustrated account, written and compiled by Carina Dennis and Richard Gallagher of "Nature", thenome project is made accessible for a general readership. It offers an introduction to the basic biology and techniques, a guide to the main players and events in the history of genetic science, and a range of viewpoints on its impact and reception around the world, in addition to the full text of the research paper itself.
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