Inductively Coupled Plasma Spectrometry and its Applications, Hill J Steve, Hooper David, Hughes James,
Автор: Gross Название: Mass Spectrometry ISBN: 3642107095 ISBN-13(EAN): 9783642107092 Издательство: Springer Рейтинг: Цена: 12571.00 р. Наличие на складе: Поставка под заказ.
Описание: This highly successful textbook, acclaimed for its comprehensiveness, accuracy, and its many excellent illustrations and photographs now comes in its second edition. Completely revised and substantially extended it offers:– New chapter on Tandem Mass Spectrometry covering instrumentation, methods for ion activation (CID, ECD, ETD, IRMPD), and applications– New chapter on Ambient Mass Spectrometry (DART, DESI, and more)– New chapter on Inorganic Mass Spectrometry including element speciation and imaging– Learning Objectives for all chapters– Advanced Instrumentation such as orbitraps, linear ion traps, tandem TOFs, FT-ICR and the highly variable hybrid instruments– Updated Problems and Solutions website (www.ms-textbook.com) J?rgen H. Gross provides in-depth explanations of concepts, methods, and techniques. Students and professionals alike are guided step-by-step from the basics to the successful application of mass spectrometry. Starting from the very principles of gas-phase ion chemistry, isotopic composition, and accurate mass, J?rgen H. Gross leads through the design of all types of mass analyzers and ionization methods to mass spectral interpretation and coupling techniques. His book offers a balanced mixture of practice-oriented information and theoretical background supported by a wealth of references.From reviews of the previous edition:“…one of the best textbooks on mass spectrometry I have seen so far.” International Journal of Mass Spectrometry“…can be recommended unreservedly as a textbook and reference source…” Angewandte Chemie, International Edition
This book deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years time-of-flight (ToF) and Orbitrap MS have both experienced a tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance.
This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of strengths and weaknesses of both techniques.
In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing: quantitative capabilities are increasingly being explored, so are non-target approaches for unbiased broad-scope screening.
In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerablewith manynovel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector but also allow insight into the advances in other fields that alsorely on hi-res MS. Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis.Explores a variety of specialized techniques Provides a general overview of imaging techniques within analysis"
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