Описание: Iron is essential for most forms of life, including humans. On the other hand, iron is also potentially toxic. Therefore, the control of iron metabolism and maintenance of iron hemostasis is an crucial part of many aspects of human health and disease. Iron deficiency anemia is one of the most common diseases worldwide, but there are also anemias associated with chronic diseases, and other acquired or hereditary defects. Understanding the control of iron metabolism is furthermore important for understanding diseases of iron overload, like hemochromatosis. This booklet is designed for physicians, clinical lab personnel and medical students. It gives an overview about the principles of regulation of iron metabolism and erythropoiesis. In addition, the various disturbances of iron metabolism and the associated clinical findings are described. Special focus lies on the differential diagnosis of the disorders, and the approaches of therapy. Finally, a comprehensive schedule of tests is included available for the determination of iron metabolism-related parameters in serum/plasma and blood, with indication of methodologies applied and reference ranges.
Описание: A panel of highly experienced neurosurgeons, neurophysiologists, neuropsychologists, and neuroanatomists join forces to create an integrated, cutting-edge survey all of the methodologies necessary for successful surgical treatment. On the surgical side they review a variety of techniques for Parkinson's disease, including thalamotomy, pallidotomy and bilateral pallidotomy, subthalamotomy, pallidal and thalamic deep brain stimulation, and subthalmic deep brain stimulation. Surgical therapy for tremor and dystonia is also covered. On the patient side, the authors systematically examine the key issues involved in any surgical procedure: Patient selection, patient assessment before and after surgery, brain target localization, and postoperative programming of brain stimulators.
Описание: This is the sixth set of Handbook of Porphyrin Science.This 5-volume set provides a comprehensive review of the most up-to-date research on porphyrin, heme and chlorophyll biochemistry, as well as applications to biomedicine and bio-inspired energy. In-depth coverage of topics along with perspectives on outstanding questions and future research directions by the authors make these volumes an essential resource for both beginning and advanced investigators in the field. It is also suitable for non-experts in porphyrin, who wish to have an overview of the fundamental discoveries and breakthroughs in the porphyrin arena related to medicine and bio-inspired energy.Bringing together the biochemistry of porphyrin-binding proteins and their clinical relevance and applications to medicine and renewable energy, this set provides readers with an integrated coverage of porphyrin biochemistry. At the same time, it challenges readers with new questions and perspectives of research regarding the role of porphyrin biochemistry in the future of medicine and renewable energy.
Описание: Disturbances of iron metabolism, particularly iron deficiency, are among the most commonly overlooked or misinterpreted diseases. This is due to the fact that the determination of transport iron in serum or plasma, which used to be the test in conventional diagnosis, does not allow a representative estimate of the bodyвЂ™s total iron reserves. A proper estimate was formerly possible only by the costly and invasive determination of storage iron in the bone marrow, however, sensitive, well-standardized immuno-chemical methods for the precise determination of the iron storage protein ferritin in plasma are now available. Since the secretion of this protein correctly reflects the iron stores in the majority of cases, these methods permit fast and reliable diagnosis, particularly of iron deficiency conditions. The fact that iron deficiency is so common and is usually simple to treat ought to be well known in the medical world.Even non-iron-determined causes of anemia can now be identified rapidly by highly sensitive, well-standardized immuno-chemical methods. This book is intended to contribute to a better understanding of the main pathophysiological foundations and diagnostic principles.
Автор: Lawrence Petz Название: Immune Hemolytic Anemias ISBN: 0443085595 ISBN-13(EAN): 9780443085598 Издательство: Elsevier Science Цена: 19454 р. Наличие на складе: Невозможна поставка.
Описание: This extensively revised edition details the management of the full range of immune hemolytic anemias. It examines the selection and interpretation of laboratory tests as well as all of today's best diagnostic and treatment methods. Readers will find the latest advances in neonatal-related disease, bone marrow transplantation-related disease, hemolytic anemia as a concomitant disorder occurring in B-cell lymphoma, certain viral entities, and more.
Описание: This book allows the movement disorder clinician or therapist access to concise, practical, comprehensive and expert information on movement disorder diagnosis and treatment, in a convenient handbook form.
Автор: Richards Название: The Human Brain & its Disorders. 2007 ISBN: 0199299846 ISBN-13(EAN): 9780199299843 Издательство: Oxford Academ Рейтинг: Цена: 4518 р. Наличие на складе: Поставка под заказ.
Описание: The first authoritative review on the parasomnias - disorders that cause abnormal behavior during sleep - this book contains many topics never before covered in detail. The behaviors associated with parasomnias may lead to injury of the patient or bed-partner, and may have forensic implications. These phenomena are common but often unrecognized, misdiagnosed, or ignored in clinical practice. With increasing awareness of abnormal behaviors in sleep, the book fulfils the need for in-depth descriptions of clinical and research aspects of these disorders, including differential diagnosis, pathophysiology, morbidity, and functional consequences of each condition, where known. Appropriate behavioral and pharmacological treatments are addressed in detail. There are authoritative sections on disorders of arousal, parasomnias usually associated with REM sleep, sleep-related movement disorders and other variants, and therapy of parasomnias. Sleep specialists, neurologists, psychiatrists, psychologists and other healthcare professionals with an interest in sleep disorders will find this book essential reading.
Описание: Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain transmission pathways. Because of its potential for managing multiple pain types, including osteoarthritis,
Описание: Conversion is very common but often misdiagnosed; even when diagnosed, treatment is difficult. It is critical for physicians to have the necessary knowledge to manage these patients in the most effective way. This volume gives all of the available, up-to-date information on when to think about conversion in movement disorders, how to make a diagnosis, how to use the laboratory to support a clinical diagnosis and how to develop a therapeutic plan. Written by experts in neurology, psychiatry, psychology, neuroimaging, neurophysiology and genetics, this book covers psychogenic movement disorders and other conversion disorders from all of the most relevant clinical angles. An accompanying CD-ROM with a video library featuring over 100 real-life examples of movement disorders will aid diagnosis. Neurologists and psychiatrists, as well as others interested in brain pathophysiology at the boundary of neurology and psychiatry, will find this a useful aid to both clinical practice and research.
Автор: Lipton Richard B Название: Migraine & Other Headache Disorders ISBN: 0849336953 ISBN-13(EAN): 9780849336959 Издательство: Informa Цена: 32539 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Following recent guidelines set by the International Classification of Headache Disorders, this reference presents the most current diagnostic and treatment protocols for migraine and other headache conditions. Chapters are authored by internationally renowned headache clinicians and scientists, including several past presidents of the American Headache Society and the International Headache Society. User-friendly and up-to-date, this reference offers useful tables, algorithms, and diagrams that lead clinicians to effective treatments for the management of migraine and the reduction of migraine severity.
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