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Drug Delivery Systems In Cancer Therapy, Brown, Dennis M.


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Цена: 20097р.
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Наличие: Поставка под заказ.  Есть в наличии на складе поставщика.
Склад Англия: 628 шт.  Склад Америка: 127 шт.  
При оформлении заказа до: 25 окт 2019
Ориентировочная дата поставки: конец Ноября

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Автор: Brown, Dennis M.
Название:  Drug Delivery Systems In Cancer Therapy   (Деннис М. Браун: Снабжение лекарственными препаратами при лечении рака)
Издательство: Springer
Классификация:
Онкология
Фармакология / отпуск лекарств

ISBN: 0896038882
ISBN-13(EAN): 9780896038882
ISBN: 0-89603-888-2
ISBN-13(EAN): 978-0-89603-888-2
Обложка/Формат: Hardback
Страницы: 400
Вес: 0.936 кг.
Дата издания: 2004
Серия: Cancer Drug Discovery and Development
Язык: ENG
Иллюстрации: 57 black & white illustrations, biography
Размер: 25.76 x 18.14 x 2.79 cm
Читательская аудитория: Postgraduate, research & scholarly
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Leading experts survey the currently available technologies designed to improve the delivery of todays cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.
Дополнительное описание: Формат: 254x178
Илюстрации: 59
Круг читателей: Experimental oncologists, pharmacologists, medicinal chemists, oncologists, and clinical pharmacologists
Ключевые слова:
Язык: eng





Ansel`s Pharmaceutical Dosage Forms and Drug Delivery Systems

Автор: Allen, Loyd
Название: Ansel`s Pharmaceutical Dosage Forms and Drug Delivery Systems
ISBN: 1469855682 ISBN-13(EAN): 9781469855684
Издательство: Lippincott Williams & Wilkins
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Цена: 5643 р. 6270.00 -10%
Наличие на складе: Поставка под заказ.

Описание: Succeed in your course with the most comprehensive source on pharmaceutical dosage forms and drug delivery systems available today. Reflecting the CAPE, APhA, and NAPLEX® competencies, this trusted resource covers physical pharmacy, pharmacy practice, pharmaceutics, compounding, and dosage forms and the clinical application of the various dosing forms in patient care. The 10th edition features a dynamic new full color design, new coverage of prescription flavoring, and additional coverage of expiration dates.   See pharmaceutical concepts in action through the two case studies (one pharmaceutical and one clinical) in each dosing forms chapter. Practice applying material using the group and individual activities in Applying the Principles and Concepts sections in every chapter. Master important underlying pharmaceutical principles through Physical Pharmacy Capsules. Extend your learning beyond the book with the online glossary and the online quiz bank that features 300 NAPLEX-style questions.Focus on what’s important with Chapter Objectives that highlight key material you need to master.

Proteasome Inhibitors in Cancer Therapy

Автор: Adams Julian
Название: Proteasome Inhibitors in Cancer Therapy
ISBN: 1588292509 ISBN-13(EAN): 9781588292506
Издательство: Springer
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Цена: 21412 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: A panel of leading academic and pharmaceutical investigators takes stock of the remarkable work that has been accomplished to date with proteasome inhibitors in cancer, and examines emerging therapeutic possibilities. The topics range from a discussion of the chemistry and cell biology of the proteasome and the rationale for proteasome inhibitors in cancer to a review of current clinical trials underway. The discussion of rationales for testing proteasome inhibitors in cancer models covers the role of the proteasome in NF-kB activation, the combining of conventional chemotherapy and radiation with proteasome inhibition, notably PS-341, new proteasome methods of inhibiting viral maturation, and the role of protesome inhibition in the treatment of AIDS. The authors also document the development of bortezomib (Velcadeв„ў) in Phase I clinical trials and in a multicentered Phase II clinical trials in patients with relapsed and refractory myeloma.

Acute Care Therapy: A Clinicians Guide

Автор: Attridge
Название: Acute Care Therapy: A Clinicians Guide
ISBN: 0071745807 ISBN-13(EAN): 9780071745802
Издательство: McGraw-Hill
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Цена: 3970 р.
Наличие на складе: Поставка под заказ.

Описание: Offers important therapeutic treatment options for the most common diseases managed by clinicians practicing internal medicine. This title also offers drug tables that include product availability, disease-specific dosing, common adverse reactions and drug/drug interactions.

Ansel`s pharmaceutical dosage forms and drug delivery systems

Название: Ansel`s pharmaceutical dosage forms and drug delivery systems
ISBN: 0781779340 ISBN-13(EAN): 9780781779340
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 4609 р. 5121.00 -10%
Наличие на складе: Поставка под заказ.

Описание: Suitable for pharmaceutics courses, this book provides a comprehensive source on pharmaceutical dosage forms and drug delivery systems. It features content that coincides with the CAPE, APhA, and NAPLEX competencies. It offers coverage that incorporates various dosage forms on the market and those in the US Pharmacopoeia-National Formulary.

Polymer Therapeutics I / Polymers as Drugs, Conjugates and Gene Delivery Systems

Автор: Satchi-Fainaro Ronit, Duncan Ruth
Название: Polymer Therapeutics I / Polymers as Drugs, Conjugates and Gene Delivery Systems
ISBN: 3540292101 ISBN-13(EAN): 9783540292104
Издательство: Springer
Рейтинг:
Цена: 27022 р.
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Описание: 1 Duncan, H. Ringsdorf, R. Satchi-Fainaro: Polymer Therapeutics: Polymers as Drugs, Drug and Protein Conjugates and Gene Delivery Systems: Past, Present and Future Opportunities.- 2 P.K. Dhal, S.R. Holmes-Farley, C.C. Huval, T.H. Jozefiak: Polymers as Drugs.- 3 R.J. Amir, D. Shabat: Domino Dendrimers.- 4 G. Pasut, F.M. Veronese: PEGylation of Proteins as Tailored Chemistry for Optimized Bioconjugates.- E. Wagner, J. Kloeckner: Gene Delivery Using Polymer Therapeutics.-  

Antiangiogenic Agents in Cancer Therapy

Автор: Teicher Beverly A.
Название: Antiangiogenic Agents in Cancer Therapy
ISBN: 0896036413 ISBN-13(EAN): 9780896036413
Издательство: Springer
Цена: 13085 р.
Наличие на складе: Поставка под заказ.

Antifolate Drugs in Cancer Therapy

Автор: Jackman Ann L.
Название: Antifolate Drugs in Cancer Therapy
ISBN: 0896035964 ISBN-13(EAN): 9780896035966
Издательство: Springer
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Цена: 21845 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This collection of cutting-edge reviews comprehensively examines the current status of novel antifolates, an important class of anticancer drugs. The distinguished contributors discuss the preclinical and clinical pharmacology of methotrexate, other dihydrofolate reductase inhibitors, 5-fluorouracil, and the new generation of antifolates-the thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. In addition, they review in depth the modulation of antifolate drugs, folate and antifolate transport mechanisms, polyglutamation, resistance, and drug combinations, as well as pharmacogenomics, pharmacodynamics, regulation of gene expression, and mechanisms of cell death. Antifolate Drugs in Cancer Therapy provides entrГ© to exciting new avenues for future research and constitutes a new standard reference for all basic scientists and clinicians engaged in cancer therapeutics.

Cell Cycle Inhibitors in Cancer Therapy

Автор: Giordano Antonio, Soprano Kenneth J.
Название: Cell Cycle Inhibitors in Cancer Therapy
ISBN: 0896039307 ISBN-13(EAN): 9780896039308
Издательство: Springer
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Цена: 21412 р.
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Описание: Leading clinicians and investigators review in a comprehensible and user-friendly style all the latest information about the molecular biology of cell cycle control and demonstrate its clinical relevance to understanding neoplastic diseases. Topics range from Cdk inhibitors and cell cycle regulators to the prognostic value of p27 and tumor suppressor genes as diagnostic tools. Actual case studies show how the new molecular understanding has produced such drugs as Flavopiridol and Sulindac. The book brings all the recent critical research findings to bear on clinical practice, and clearly shows their powerful impact on the diagnostics, prognostics, and therapeutics of cancer, AIDS, and cardiovascular disease.

Polymer Therapeutics II / Polymers as Drugs, Conjugates and Gene Delivery Sytems

Автор: Satchi-Fainaro Ronit, Duncan Ruth
Название: Polymer Therapeutics II / Polymers as Drugs, Conjugates and Gene Delivery Sytems
ISBN: 354029211X ISBN-13(EAN): 9783540292111
Издательство: Springer
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Цена: 27022 р.
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Описание: With contributions by numerous experts

Managing Oral Anticoagulation Therapy, Clinical and Operational Guidelines, 3e

Автор: Ansell
Название: Managing Oral Anticoagulation Therapy, Clinical and Operational Guidelines, 3e
ISBN: 1574392875 ISBN-13(EAN): 9781574392876
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 19646 р.
Наличие на складе: Поставка под заказ.

Описание: Clinical and Operational Guidelines. Managing Oral Anticoagulation Therapy Clinical and Operational Guidelines provides the resources and information to enhance the care of patients receiving oral anticoagulation therapy. Written by a diverse and multidisciplinary group of health care professionals with handson experience, this book focuses on the anticoagulation management servicea model of anticoagulation care that is systematic, organized, and coordinated.

All aspects of development and implementation of this care model are addressed. The book is divided into two sections Part 1, Establishing an Anticoagulation

Farnesyltransferase Inhibitors in Cancer Therapy

Автор: Sebti SaГЇd M., Hamilton Andrew D.
Название: Farnesyltransferase Inhibitors in Cancer Therapy
ISBN: 0896036294 ISBN-13(EAN): 9780896036291
Издательство: Springer
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Цена: 14959 р.
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Описание: Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific and medical aspects of farnesyltransferase inhibitors. Signal Transduction Pathways: A Goldmine for Therapeutic Targets, Paul Workman. The Biochemistry of Farnesyltransferase and Geranylgeranyltransferase I, Chih-Chin Huang, Carol A. Fierke, and Patrick J. Casey. Structures of Protein Farnesyltransferase, Stephen B. Long and Lorena S. Beese. Peptidomimetic-Based Inhibitors of Farnesyltransferase, David Knowles, Jiazhi Sun, Saul Rosenberg, SaГЇd M. Sebti, and Andrew D. Hamilton. Antitumor Efficacy of a Farnesyltransferase Inhibitor in Transgenic Mice, Jackson B. Gibbs, Samuel L. Graham, George D. Hartman, Kenneth S. Koblan, Nancy E. Kohl, Charles Omer, Angel Pellicier, Jolene Windle, and Allen Oliff. Development of Farnesyltransferase Inhibitors as Potential Antitumor Agents, Veeraswamy Manne, Frank Lee, Ning Yan, Craig Fairchild, and William C. Rose. Tricyclic Farnesyl Protein Transferase Inhibitors: Antitumor Activity and Effects on Protein Prenylation, W. Robert Bishop, James J.-K. Pai, Lydia Armstrong, Marguerite B. Dalton, Ronald J. Doll, Arthur Taveras, George Njoroge, Michael Sinensky, Fang Zhang, Ming Liu, and Paul Kirschmeier. Histidylbenzylglycinamides: A Novel Class of Farnesyl Diphosphate-Competitive Peptidic Farnesyltransferase Inhibitors, Judith S. Sebolt-Leopold, Daniele M. Leonard, and W. R. Leopold. From Random Screening of Chemical Libraries to the Optimization of FPP-Competitive Inhibitors of Farnesyltransferase, Patrick Mailliet, Abdel Laoui, Jean-Dominique Bourzat, Marc Capet, Michel ChevГ©, Alain CommerГ§on, Norbert Dereu, Alain LeBrun, Jean-Paul Martin, Jean-FranГ§ois Peyronel, Christophe Salagnad, Fabienne Thompson, Martine Zucco, Jean-Dominique Guitton, Guy Pantel, Marie-Christine Bissery, Clive Brealey, Jacques Lavayre, Yves LeliГЁvre, Jean-FranГ§ois Riou, Patricia Vrignaud, Marc Duchesne, and FranГ§ois Lavelle. Genetic Analysis of FTase and GGTase I and Natural Product Farnesyltransferase Inhibitors, Fuyuhiko Tamanoi, Keith Del Villar, Nicole Robinson, MeeRhan Kim, Jun Urano, and Wenli Yang. Effects of Farnesyltransferase Inhibitors on Cytoskeleton, Cell Transformation, and Tumorigenesis: The FTI-Rho Hypothesis, George C. Prendergast. Prenyltransferase Inhibitors as Radiosensitizers, Eric J. Bernhard, Ruth J. Muschel, Elizabeth Cohen-Jonathan, Gilles Favre, Andrew D. Hamilton, SaГЇd M. Sebti, and W. Gillies McKenna. Farnesyltransferase and Geranylgeranyltransferase I Inhibitors as Novel Agents for Cancer and Cardiovascular Diseases, SaГЇd M. Sebti and Andrew D. Hamilton. Protein Prenylation in Trypanosomatids: A New Piggy-Back Medicinal Chemistry Target for the Development of Agents Against Tropical Diseases, Michael H. Gelb, Frederick S. Buckner, Kohei Yokoyama, Junko Ohkanda, Andrew D. Hamilton, Lisa Nguyen, Bartira Rossi-Bergmann, Kenneth D. Stuart, SaГЇd M. Sebti, and Wesley C. Van Voorhis. Early Clinical Experience with Farnesyl Protein Transferase Inhibitors: From the Bench to the Bedside, Amita Patnaik and Eric K. Rowinsky. Phase I Trial of Oral R115777 in Patients with Refractory Solid Tumors: Preliminary Results, Gary R. Hudes and Jessie Schol. Farnesyltransferase and Geranylgeranyltransferase Inhibitors: The Saga Continues, Adrienne D. Cox, L. Gerard Toussaint III, James J. Fiordalisi, Kelley Rogers-Graham, and Channing J. Der. Index.

Tumor Targeting in Cancer Therapy

Автор: PagГ© Michel
Название: Tumor Targeting in Cancer Therapy
ISBN: 0896039196 ISBN-13(EAN): 9780896039193
Издательство: Springer
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Цена: 23282 р.
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Описание: In Tumor Targeting in Cancer Therapy, Dr. Michel PagГ© and a panel of authoritative experts from the drug industry, clinics, and academia introduce the principles and techniques of tumor targeting and critically survey their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme prodrug immunotherapy, and immunotherapeutics with fusion proteins. There are also reviews of targeting tumors with radioimmunoconjugates, photodynamic therapy, and magnetic drugs, as well as discussions of the internalization of antibodies, bioconjugation and biodistribution, the use of cytotoxic drugs, and the pros and cons of targeting by antibody or ligand.


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