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Single Nucleotide Polymorphisms / Methods and Protocols, Kwok Pui-Yan
Single Nucleotide Polymorphisms / Methods and Protocols

Автор: Kwok Pui-Yan
Название:  Single Nucleotide Polymorphisms / Methods and Protocols   (Полиморфизм нуклеотида / методы и протоколы)
Издательство: Springer
Медицинская генетика

ISBN: 0896039684
ISBN-13(EAN): 9780896039681
ISBN: 0-89603-968-4
ISBN-13(EAN): 978-0-89603-968-1
Обложка/Формат: Hardcover
Страницы: 288
Вес: 0.593 кг.
Дата издания: 2003
Серия: Methods in Molecular Biology
Язык: ENG
Размер: 23.52 x 15.85 x 2.08 cm
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
Дополнительное описание: Формат: 229x152
Илюстрации: 60
Круг читателей: Researchers interested in genetic studies, including association studies of common diseases in humans, DNA diagnostics, forensics, and agricultural biotechnology
Ключевые слова:
Язык: eng

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Human Chromosome Variation: Heteromorphism and Polymorphism

Автор: Wyandt
Название: Human Chromosome Variation: Heteromorphism and Polymorphism
ISBN: 9400708955 ISBN-13(EAN): 9789400708952
Издательство: Springer
Цена: 13877 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Human Chromosome Variation: Heteromorphism and Polymorphism was formerly printed under the title “Atlas of Human Chromosome Heteromorphism”. The Atlas has become a standard reference book in most cytogenetic laboratories and is cited as a significant reference in ISCN 2009. This revised version has updated and retained the most useful pictorial sections of the first edition, including the comprehensive review of normal and “not-so-normal” variations of the human karyotype with summaries and extensive reference lists organized by chromosome number. This updated edition features concise background information on chromosome methods and applications, essential information on heteromorphism frequencies in normal and clinical populations as well as new listing and discussions of euchromatic, subtelomeric and FISH variants. The addition of two new sections make this an even more valuable reference than before. A section on common and rare fragile sites includes a short historical discussion, definitions and an extensive table of officially recognized sites that includes the HUGO name, chromosomal location, methods of induction, genes and references to the most recent molecular characterization. A new section on array CGH discusses the clinical challenge of interpreting copy number variations (CNVs) revealed by this newest technology, gives examples of various levels of interpretation and lists the several most common websites used in this interpretation.

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Human Nucleotide Expansion Disorders

Автор: Fry Michael, Usdin Karen
Название: Human Nucleotide Expansion Disorders
ISBN: 3540333355 ISBN-13(EAN): 9783540333357
Издательство: Springer
Цена: 26318 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Human neurological and neuromuscular disorders caused by nucleotide expansion, first discovered in 1991, are the focus of growing interest of practicing physicians and of interested biomedical researchers. This volume represents a comprehensive and up-to-date description of many of the better-studied disorders. The expert authors discuss molecular, clinical and pathological aspects of the diseases as well as our current understanding of their underlying mechanisms. Of special interest are ideas and initial results of the different therapeutic strategies that can be employed to overcome some of the disorders. As a summary of the state-of-the-art research in this field, this book is of value to human geneticists, molecular biologists and biochemists as well as to practicing neurologists and pediatricians.

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Single Nucleotide Polymorphisms

Автор: Komar
Название: Single Nucleotide Polymorphisms
ISBN: 1603274103 ISBN-13(EAN): 9781603274104
Издательство: Springer
Цена: 10724 р.
Наличие на складе: Нет в наличии.

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Cytokine Gene Polymorphisms in Multifactorial Conditions

Автор: Koen Vandenbroeck
Название: Cytokine Gene Polymorphisms in Multifactorial Conditions
ISBN: 0849336198 ISBN-13(EAN): 9780849336195
Издательство: Taylor&Francis
Цена: 8602 р.
Наличие на складе: Поставка под заказ.

Описание: Written by the leading specialists, this book brings together, reviews, and structures up-to-date information on polymorphisms in cytokine genes. While the beginning chapters discuss the properties of individual cytokines, in the later chapters cytokines are re-presented considering the individual disease or condition. Broadening understanding of the effect of genetic variations on human immune responses, the organization, scope, and content of this book make it a valuable and easily accessible resource. A reference for geneticists, immunologists, cell biologists and clinicians, the book is a must for everyone involved in, or planning, cytokine genetics or immunogenetics studies.

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