Proteomics of Human Bodyfluids / Principles, Methods, and Applications, Thongboonkerd Visith

Автор: Gary B. Smejkal and Alexander Lazarev
Название: Separation Methods In Proteomics
ISBN: 0824726995 ISBN-13(EAN): 9780824726997
Издательство: Taylor&Francis
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Цена: 33686.00 р.
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Описание: Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. "Separation Methods in Proteomics" provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems.

Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis.Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated 'subproteomes' for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, "Separation Methods in Proteomics" contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.

Автор: Agarwal
Название: Proteomics in Human Reproduction
ISBN: 3319484168 ISBN-13(EAN): 9783319484167
Издательство: Springer
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Цена: 7685.00 р.
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Описание: This Brief explores the use of proteomics as a tool for biomarker discovery in human reproduction and summarizes current findings and trends of proteomic studies in both male and female infertility. This simplifies this important but complex topic and equips the novice reader with sufficient background information on the use of proteomics in human reproduction. The up-to-date scenario on proteomic investigations will also appeal to researchers and post graduate students looking to keep abreast with the latest developments in reproductive research. This review summarizes current findings of contemporary proteomic studies on infertility in both males and females with various reproductive pathologies, and its use in predicting the outcome of assisted reproduction. In human reproduction, the search for biomarkers via proteomics is a fast-evolving approach that involves the analysis of proteins in the reproductive tissues and fluids, such as the male gametes, seminal plasma, ovarian and endometrial tissue, and follicular and uterine fluid. By comparing the protein profile of a healthy, fertile individual against that of an infertile individual, the differentially expressed proteins may give an indication to certain proteins that could serve as useful biomarkers that are related to infertility. As proteomic studies continue to unravel the dynamic proteome behind various infertility conditions, there is potential for the discovery of prognostic markers that could ultimately help in both natural and assisted human reproduction.

Автор: Matthiesen Rune
Название: Mass Spectrometry Data Analysis in Proteomics
ISBN: 158829563X ISBN-13(EAN): 9781588295637
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Aims to support researchers in deciding which programs to use in various tasks related to analysis of mass spectrometry data in proteomics. This work covers chapters that give a description of the theoretical background of each topic followed by descriptions of programs and the parameters best suited for different cases.

Автор: Hubert Rehm
Название: Protein Biochemistry and Proteomics,
ISBN: 012088545X ISBN-13(EAN): 9780120885459
Издательство: Elsevier Science
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Цена: 8251.00 р.
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Описание: Connects concepts and creates links to criminal behavior across crimes murder, sexual assault, and arson. This work provides a theoretical and practical foundation for understanding the motivation and dynamics in a range of serial offenses. It includes case examples that offer real-world uses of behavioral profiling in investigations.