Автор: Stephen W. Looney Название: Biostatistical Methods ISBN: 1617372714 ISBN-13(EAN): 9781617372711 Издательство: Springer Рейтинг: Цена: 16196 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading biostatisticians and biomedical researchers describe many of the key techniques used to solve commonly occurring data analytic problems in molecular biology, and demonstrate how these methods can be used in the development of new markers for exposure to a risk factor or for disease outcomes.
Описание: Topics from modern cancer clinical trials include phase I clinical trials for combination therapies, exploratory phase II trials with multiple endpoints/treatments, and confirmative biomarker-based phase III trials with interim monitoring and adaptation.
Описание: The topical areas include active areas of the application of biostatistics to modern cancer research: survival analysis, screening, diagnostics, spatial analysis and the analysis of microarray data.Biostatistics is an essential component of basic and clinical cancer research.
Автор: Vexler Название: Biostatistical Methods ISBN: 1138196894 ISBN-13(EAN): 9781138196896 Издательство: Taylor&Francis Рейтинг: Цена: 11550 р. Наличие на складе: Поставка под заказ.
Описание: "This very informative book introduces classical and novel statistical methods that can be used by theoretical and applied biostatisticians to develop efficient solutions for real-world problems encountered in clinical trials and epidemiological studies. The authors provide a detailed discussion of methodological and applied issues in parametric, semi-parametric and nonparametric approaches, including computationally extensive data-driven techniques, such as empirical likelihood, sequential procedures, and bootstrap methods. Many of these techniques are implemented using popular software such as R and SAS."— Vlad Dragalin, Professor, Johnson and Johnson, Spring House, PA "It is always a pleasure to come across a new book that covers nearly all facets of a branch of science one thought was so broad, so diverse, and so dynamic that no single book could possibly hope to capture all of the fundamentals as well as directions of the field. The topics within the book’s purview—fundamentals of measure-theoretic probability; parametric and non-parametric statistical inference; central limit theorems; basics of martingale theory; Monte Carlo methods; sequential analysis; sequential change-point detection—are all covered with inspiring clarity and precision. The authors are also very thorough and avail themselves of the most recent scholarship. They provide a detailed account of the state of the art, and bring together results that were previously scattered across disparate disciplines. This makes the book more than just a textbook: it is a panoramic companion to the field of Biostatistics. The book is self-contained, and the concise but careful exposition of material makes it accessible to a wide audience. This is appealing to graduate students interested in getting into the field, and also to professors looking to design a course on the subject." — Aleksey S. Polunchenko, Department of Mathematical Sciences, State University of New York at Binghamton This book should be appropriate for use both as a text and as a reference. This book delivers a "ready-to-go" well-structured product to be employed in developing advanced courses. In this book the readers can find classical and new theoretical methods, open problems and new procedures. The book presents biostatistical results that are novel to the current set of books on the market and results that are even new with respect to the modern scientific literature. Several of these results can be found only in this book.
Автор: Commenges Название: Dynamical Biostatistical Models ISBN: 1498729673 ISBN-13(EAN): 9781498729673 Издательство: Taylor&Francis Рейтинг: Цена: 8315 р. Наличие на складе: Поставка под заказ.
Описание: Dynamical Biostatistical Models presents statistical models and methods for the analysis of longitudinal data. The book focuses on models for analyzing repeated measures of quantitative and qualitative variables and events history, including survival and multistate models. Most of the advanced methods, such as multistate and joint models, can be applied using SAS or R software. The book describes advanced regression models that include the time dimension, such as mixed-effect models, survival models, multistate models, and joint models for repeated measures and time-to-event data. It also explores the possibility of unifying these models through a stochastic process point of view and introduces the dynamic approach to causal inference. Drawing on much of their own extensive research, the authors use three main examples throughout the text to illustrate epidemiological questions and methodological issues. Readers will see how each method is applied to real data and how to interpret the results.
Описание: Praise for the First Edition ". . . an excellent textbook . . . an indispensable reference for biostatisticians and epidemiologists."?—International Statistical Institute A new edition of the definitive guide to classical and modern methods of biostatisti
Описание: The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in the healthcare field. The book provides valuable insight on where to look for information and material on sample size and statistical techniques commonly used in clinical research, and on how best to communicate with clinicians. It also covers the best practices to adopt in terms of project, time, and data management; relationship with collaborators; etc.
Автор: Lawrence L. Kupper, Sean M. O`Brien and Brian H. N Название: Problems and Solutions in Biostatistical Theory ISBN: 1584887222 ISBN-13(EAN): 9781584887225 Издательство: Taylor&Francis Рейтинг: Цена: 4157 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Drawn from nearly four decades of Lawrence L. Kupper 's teaching experiences as a distinguished professor in the Department of Biostatistics at the University of North Carolina, Exercises and Solutions in Biostatistical Theory presents theoretical statistical concepts, numerous exercises, and detailed solutions that span topics from basic probability to statistical inference. The text links theoretical biostatistical principles to real-world situations, including some of the authors own biostatistical work that has addressed complicated design and analysis issues in the health sciences.
This classroom-tested material is arranged sequentially starting with a chapter on basic probability theory, followed by chapters on univariate distribution theory and multivariate distribution theory. The last two chapters on statistical inference cover estimation theory and hypothesis testing theory. Each chapter begins with an in-depth introduction that summarizes the biostatistical principles needed to help solve the exercises. Exercises range in level of difficulty from fairly basic to more challenging (identified with asterisks).
By working through the exercises and detailed solutions in this book, students will develop a deep understanding of the principles of biostatistical theory. The text shows how the biostatistical theory is effectively used to address important biostatistical issues in a variety of real-world settings. Mastering the theoretical biostatistical principles described in the book will prepare students for successful study of higher-level statistical theory and will help them become better biostatisticians.
Описание: Biostatistics is defined as much by its application as it is by theory. This book provides an introduction to biostatistical applications in modern cancer research that is both accessible and valuable to the cancer biostatistician or to the cancer researcher, learning biostatistics. The topical areas include active areas of the application of biostatistics to modern cancer research: survival analysis, screening, diagnostics, spatial analysis and the analysis of microarray data.Biostatistics is an essential component of basic and clinical cancer research. The text, authored by distinguished figures in the field, addresses clinical issues in statistical analysis. The spectrum of topics discussed ranges from fundamental methodology to clinical and translational applications.
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