Описание: Advances in cytogenetics continue to crop up in wonderful ways, and we know exponentially more about chromosomes now than mere decades ago. Likewise, the necessary skills in offering genetic counseling continue to evolve. This new edition of Chromosome Abnormalities in Genetic Counseling offers a practical, up-to-date guide for the genetic counselor to marshal cytogenetic data and analysis clearly and effectively to families.
Автор: Rossen Donev Название: Organisation of Chromosomes,90 ISBN: 0124105238 ISBN-13(EAN): 9780124105232 Издательство: Elsevier Science Рейтинг: Цена: 12062 р. Наличие на складе: Невозможна поставка.
Описание: Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.
Описание: Describes not only the classic methods, but also the various novel techniques for the transfer of large DNAs into the cells of both microbes and animals via large-insert recombinant DNAs. This book provides a variety of methods and applications for functional analysis of DNA-transformed organisms.
Автор: Sumner Название: Chromosomes.2002 ISBN: 0632054077 ISBN-13(EAN): 9780632054077 Издательство: Wiley Цена: 3130 р. Наличие на складе: Поставка под заказ.
Описание: Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour of chromosomes is central to genetics and the equal segregation of genes and chromosomes into daughter cells at cell division is vital. This text aims to provide a clear and straightforward explanation of these complex processes.Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNA replication; mitosis and
Описание: Human beings normally have a total of 46 chromosomes, with each chromosome present twice, apart from the X and Y chromosomes in males. Some three million people worldwide, however, have 47 chromosomes: they have a small supernumerary marker chromosome (sSMC) in addition to the 46 normal ones. This sSMC can originate from any one of the 24 human chromosomes and can have different shapes. Approximately one third of sSMC carriers show clinical symptoms, while the remaining two thirds manifest no phenotypic effects.This guide represents the first book ever published on this topic. It presents the latest research results on sSMC and current knowledge about the genotype-phenotype correlation. The focus is on genetic diagnostics as well as on prenatal and fertility-related genetic counseling. A unique feature is that research meets practice: numerous patient reports complement the clinical aspects and depict the experiences of families living with a family member with an sSMC.
Описание: With numerous case studies complementing the theoretical aspects of the subject, and focusing on genetic diagnostics as well as on prenatal and fertility-related genetic counseling, this book is the first of its kind and includes the latest research on sSMCs.
Автор: Sgaramella Vittorio, Eridani Sandro Название: Mammalian Artificial Chromosomes ISBN: 1588290964 ISBN-13(EAN): 9781588290960 Издательство: Springer Рейтинг: Цена: 11219 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading scientists in cell biology, genetics, cell culturing, and gene transfer present their most productive methods for the preparation, characterization, and use of artificial chromosomes. The authors cover all relevant areas of artificial chromosome research-from basic genetics to daring attempts at building new gene therapy tools-and describe possible applications in genetic manipulation requiring large portions of the genome. Each fully tested protocol is described in step-by-step detail and includes a background introduction outlining the principle behind the technique, reagent and equipment lists, and tips on troubleshooting and how to avoid pitfalls.
Описание: Human Chromosome Variation: Heteromorphism and Polymorphism was formerly printed under the title “Atlas of Human Chromosome Heteromorphism”. The Atlas has become a standard reference book in most cytogenetic laboratories and is cited as a significant reference in ISCN 2009. This revised version has updated and retained the most useful pictorial sections of the first edition, including the comprehensive review of normal and “not-so-normal” variations of the human karyotype with summaries and extensive reference lists organized by chromosome number. This updated edition features concise background information on chromosome methods and applications, essential information on heteromorphism frequencies in normal and clinical populations as well as new listing and discussions of euchromatic, subtelomeric and FISH variants. The addition of two new sections make this an even more valuable reference than before. A section on common and rare fragile sites includes a short historical discussion, definitions and an extensive table of officially recognized sites that includes the HUGO name, chromosomal location, methods of induction, genes and references to the most recent molecular characterization. A new section on array CGH discusses the clinical challenge of interpreting copy number variations (CNVs) revealed by this newest technology, gives examples of various levels of interpretation and lists the several most common websites used in this interpretation.
Автор: Wyandt Herman E., Tonk Vijay S. Название: Atlas of Human Chromosome Heteromorphisms ISBN: 1402013035 ISBN-13(EAN): 9781402013034 Издательство: Springer Рейтинг: Цена: 19224 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is not a panacea. However, it does provide, for the first time in one place, a comprehensive view of human chromosome heteromorphisms, their applications, and their often speculated roles in aberrant chromosome behaviour relating to abnormal phenotype, pregnancy loss and cancer. More significantly, the book is a pictorial atlas for common and unusual heteromorphisms and euchromatic variants as they have been studied both by classical banding techniques and by newer molecular or FISH technologies. To facilitate its use as a laboratory or clinical reference, plates in a pictorial section are organized by chromosome number with the most recent ISCN ideogram, summary and extensive list of references for each chromosome. A final pictorial section is devoted to FISH variants. The book is a work in progress, with submission of new variants encouraged for future editions
Описание: Contains information on the molecular organization of the chromosome. This book is suitable for those in the biotechnological industry.
Автор: Miller Название: Human Chromosomes ISBN: 0387950311 ISBN-13(EAN): 9780387950310 Издательство: Springer Рейтинг: Цена: 10485 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The fourth edition of this well-known text provides students, researchers, and technicians in the area of medicine, genetics, and cell biology with a concise,
understandable introduction to the structure and behavior of human chromosomes. It covers both basic and up-to-date material on normal and defective chromosomes. This new edition
is particularly strengthened by the complete revision of the material on the molecular genetics of chromosomes and chromosomal defects.
The mapping and molecular analysis
of chromosomes is one of the most exciting and active areas of modern biomedical research, and this book will be invaluable to scientists, students, technicians and physicians with an
interest in the function and dysfunction of chromosomes. From the reviews of the third edition: "Each word "tells" in this concise gem of a human cytogenetics text...Superb organization
makes this an excellent text...for any cytogenetics course." - "American Journal of Human Genetics". "...the leading textbook in English on human cytogenetics." - "Cell".
Автор: Olmo Название: Chromosomes Today ISBN: 3764357991 ISBN-13(EAN): 9783764357993 Издательство: Springer Рейтинг: Цена: 21412 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "Chromosomes Today, Volume 13" includes the plenary lectures presented at the 13th International Chromosome Conference, covering the most recent
advances in the studies on chromosomes. The contributions in this volume were presented by some of the world's leaders in cytogenetic and molecular research and outline the present
status of knowledge on the composition, structure, function and evolution of chromosomes, including, among others, the advancement of the human genome project. The use of
cytogenetic studies has greatly increased in the last few years, resulting in a progressive improvement in the available methods that has consequently allowed a more detailed analysis of
the molecular organization of eukaryotic chromosomes and a precise in situ localisation of specific gene sequences.
This volume of "Chromosomes Today" provides
up-to-date information regarding the to
ics at the forefront of chromosome research: genetic regulation, imprinting, DNA duplication and meiotic pairing.
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