Molecular Basis of Breast Cancer / Prevention and Treatment, Russo Jose, Russo Irma H.
Автор: Mendelsohn, John Название: The Molecular Basis of Cancer ISBN: 1455740667 ISBN-13(EAN): 9781455740666 Издательство: Elsevier Science Рейтинг: Цена: 19865 р. Наличие на складе: Поставка под заказ.
Описание: Arms you with the advances in the battle against cancer. This title explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease.
Описание: The book focuses on the understanding of molecular pathways by which normal cell progress to the definable stage of cancer. The chapters explore microbiota and chronic inflammation, multiple myeloma chemoprevention, microRNAs, cancer regulation, liquid biopsies, and angiogenesis. Recent advances of molecular risk assessment, tumor microenvironment, microneoplasia, malignant gene expressions are highlighted to provide a means and design of future cancer prevention strategies and challenges thereupon. The volume also explores various receptor drugs that are in development process with the emphasis of inhibitors used to prevent malignant gene expression. The book bridges the gap between basic science and clinical application of current knowledge of cancer and emphasizes that tumor progression and cancer metastasis are not random - treatments and cure are logical and eventual.
Expertly authored and drawing from a wealth of international perspectives, Molecular Targets and Strategies in Cancer Prevention is invaluable reading for clinicians and researchers in the fields of oncology and molecular biology.
Описание: Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, including a practice-oriented review of its diagnosis, evaluation, and treatment. The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic. The book also elucidates the creation and effective deployment of treatment guidelines introduced by third party payers to improve clinical outcomes, even while lowering healthcare costs.
Описание: Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to r
Автор: Badve Название: Molecular Pathology of Breast Cancer ISBN: 3319417592 ISBN-13(EAN): 9783319417592 Издательство: Springer Рейтинг: Цена: 23747 р. Наличие на складе: Поставка под заказ.
Описание: The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques. The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics,“Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.
Описание: This book addresses the day-to-day treatment planning issues that radiation oncologists are likely to encounter during the treatment of breast cancer patients and provides numerous practical “tips” that will assist in navigation of the treatment planning process, from delineation of the tumor boundaries to discrimination of adjacent normal tissues and critical structures at risk of radiation injury. Differences in target delineation and treatment planning according to technique are emphasized, with coverage of conventional radiation therapy and advanced techniques including cardiac-sparing approaches, e.g., using active breathing control, intensity-modulated radiation therapy, proton beam therapy, and electron beam therapy post mastectomy. Individual chapters also focus on radiation setup and verification techniques and radiation treatment planning systems. The book, which is part of the Springer series Practical Guides in Radiation Oncology, is designed for hands-on use by radiation oncology residents/fellows in training and practicing radiation oncologists.
Описание: Winner: 2014 IPPY Book Award, Bronze - Health, 2014 NIEA Indie Excellence Award, 2014 Association Media and Publishing EXCEL Award, Silver, 2014 National Health Information, Silver, Patient Education Information, 2013 USA Best Book Award, Health - Cancer ------ Offering encouragement and support, this updated guide is the authority on coping with breast cancer. Highlighting all the latest medical developments, from diagnosis through treatment and recovery, this essential book guides newly diagnosed patients every step of the way. Including practical tips on managing the emotions, reactions, and side effects of breast cancer and its treatment, detailed questions to ask a medical team for empowerment, and wellness plans for recovery and life after cancer, this comprehensive manual is packed with information to best manage the breast cancer experience.
Описание: After her diagnosis of triple negative breast cancer (TNBC), health journalist Patricia Prijatel did what any reporter would do: start investigating the disease, how it occurs, and how it`s treated. While she learned that important research was emerging, she found a noticeable lack of resources on the disease, which affects 70,000 women a year and differs from hormone-positive breast cancer in important ways, including prognosis and treatment options. InSurviving-Triple Negative Breast Cancer, Prijatel delivers research-based information on the biology of TNBC; the role of genetics, family history, and race; how to navigate treatment options; and a plethora of strategies to reduce the risk of recurrence. Woven throughout the book are stories of women who havefaced TNBC: mothers, wives, daughters, and sisters who went through a variety of medical treatments and then got on with life.
Описание: Provides an overview of the techniques, agents and approaches for breast cancer and its treatment. This book presents organ-specific approaches and their impact on the re-classification of breast cancer. It also addresses the integration of biological markers, technologies, diagnostic and therapeutic approaches into clinical trials and practice.
Описание: The book`s many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis.
Автор: Monica Castiglione; Martine J. Piccart (Eds.) Название: Adjuvant Breast Cancer Treatment ISBN: 0387751149 ISBN-13(EAN): 9780387751146 Издательство: Springer Рейтинг: Цена: 32225 р. Наличие на складе: Поставка под заказ.
Описание: Adjuvant treatment is administered prior to, or as follow up to, surgical procedures for breast cancer. However, this book offers a unique perspective on the topic; all contributors are female, except for one male breast cancer survivor.
Автор: Mina Название: Breast Cancer Prevention and Treatment ISBN: 3319194364 ISBN-13(EAN): 9783319194363 Издательство: Springer Рейтинг: Цена: 8084 р. Наличие на складе: Поставка под заказ.
Описание: Uniquelydesigned for oncologists and general practitioners, this book offers clinicianscomprehensive guidelines when dealing with women at high risk for breastcancer. Written by experts in the field on the cutting edge of this research,the following questions will be answered for the reader by the end of the book:· Who is at elevated risk for breast cancer?· Who should be genetically screened?· When and how often should we obtain imaging?· What type of imaging is adequate?· What medications are available for prevention?· When is surgical intervention appropriate?· What lifestyle changes should be implemented to prevent thisdisaster?With one in eight women likely to contract breast cancer in herlifetime, the significance of identifying and managing the high-risk patient isevident. Breakthroughs in the identification of genes associated with breastcarcinoma, particularly BRCA1 and 2,as well as other risk factors, influence not only how patients are screened,but also how they are treated. Breast Cancer Prevention and Treatment providesa guided approach to prevention of breast cancer in women at elevated risk forthis malignancy.
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