A Practical Approach to Microarray Data Analysis, Berrar Daniel P., Dubitzky Werner, Granzow Martin
Автор: Zhang Aidong Название: Advanced analysis of gene expression microarray data ISBN: 9812566457 ISBN-13(EAN): 9789812566454 Издательство: World Scientific Publishing Рейтинг: Цена: 9318 р. Наличие на складе: Есть (4 шт.) Описание: This book focuses on the development and application of the latest advanced data mining, machine learning, and visualization techniques for the identification of interesting, significant, and novel patterns in gene expression microarray data.Biomedical researchers will find this book invaluable for learning the cutting-edge methods for analyzing gene expression microarray data. Specifically, the coverage includes the following state-of-the-art methods:Ȣ Gene-based analysis: the latest novel clustering algorithms to identify co-expressed genes and coherent patterns in gene expression microarray data setsȢ Sample-based analysis: supervised and unsupervised methods for the reduction of the gene dimensionality to select significant genes. A series of approaches to disease classification and discovery are also describedȢ Pattern-based analysis: methods for ascertaining the relationship between (subsets of) genes and (subsets of) samples. Various novel pattern-based clustering algorithms to find the coherent patterns embedded in the sub-attribute spaces are discussedȢ Visualization tools: various methods for gene expression data visualization. The visualization process is intended to transform the gene expression data set from high-dimensional space into a more easily understood two- or three-dimensional space.
Автор: Mark Schena Название: Microarray Analysis ISBN: 0471414433 ISBN-13(EAN): 9780471414438 Издательство: Wiley Рейтинг: Цена: 19058 р. Наличие на складе: Поставка под заказ.
Описание: * Provides a working knowledge of applications to a broad spectrum of disciplines. * Includes coverage of bioinformatics, novel arrays, and applications for clinical studies. * Supplemented with a separate chapter on the business of the technology.
Автор: Jonathan R. Pollack (Ed.) Название: Microarray Analysis of the Physical Genome ISBN: 1603271910 ISBN-13(EAN): 9781603271912 Издательство: Springer Рейтинг: Цена: 15151 р. Наличие на складе: Поставка под заказ.
Описание: Covers DNA micro array applications for the detection and characterization of genomic DNA-associated copy number alteration, loss of heterozygosity (LOH), cytosine methylation, protein binding sites, regulatory elements, and replication timing, with an emphasis on higher eukaryote (animal) and cancer genomes.
Автор: Fraser Название: Microarray Image Analysis ISBN: 1420091530 ISBN-13(EAN): 9781420091533 Издательство: Taylor&Francis Рейтинг: Цена: 11118 р. Наличие на складе: Невозможна поставка.
Описание: To harness the high-throughput potential of DNA microarray technology, it is crucial that the analysis stages of the process are decoupled from the requirements of operator assistance. This book presents an automatic system for microarray image processing to make this decoupling a reality. The proposed system integrates and extends traditional analytical-based methods and custom-designed novel algorithms. The authors cover many new approaches for processing microarray images, such as novel subgrid detection, feature identification, and graph-cutting techniques. They include details of the algorithmic processes along with an analysis of the processes performance over real-world microarray image data.
Автор: Wu Название: Protein Microarray for Disease Analysis ISBN: 1617790427 ISBN-13(EAN): 9781617790423 Издательство: Springer Рейтинг: Цена: 15151 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein microarrays have been used for a wide variety of important tasks, such as identifying protein-protein interactions, discovering disease biomarkers, identifying DNA-binding specificity by protein variants, and for characterization of the humoral immune response. In Protein Microarray for Disease Analysis: Methods and Protocols, expert researchers provide concise descriptions of the methodologies currently used to fabricate microarrays for the comprehensive analysis of proteins or responses to proteins that can be used to dissect human disease. These methodologies are the toolbox for revolutionizing drug development and cell-level biochemical understanding of human disease processes. Beginning with a section on protein-detecting analytical microarrays, the volume continues with sections covering antigen microarrays for immunoprofiling, protein function microarrays, the validation of candidate targets, proteomic libraries, as well as signal detection strategies and data analysis techniques. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, Protein Microarray for Disease Analysis: Methods and Protocols serves as a solid framework to aid scientists in understanding how protein microarray technology is presently developing and how it can be applied to transform our analysis of human disease.
Автор: Geoffrey J. McLachlan Название: Analyzing Microarray Gene Expression Data ISBN: 0471226165 ISBN-13(EAN): 9780471226161 Издательство: Wiley Рейтинг: Цена: 15246 р. Наличие на складе: Поставка под заказ.
Описание: With emphasis on clustering of data of gene tissues, this book includes fresh research findings and activities in molecular biology. It highlights the important general field of bioinformatics and genomics and discusses the impact of microarray analysis on both.
Автор: Dov Stekel Название: Microarray Bioinformatics ISBN: 052152587X ISBN-13(EAN): 9780521525879 Издательство: Cambridge Academ Рейтинг: Цена: 4140 р. Наличие на складе: Невозможна поставка.
Описание: This book is a comprehensive guide to all of the mathematics, statistics and computing you will need to successfully operate DNA microarray experiments. It is written for researchers, clinicians, laboratory heads and managers, from both biology and bioinformatics backgrounds, who work with, or who intend to work with microarrays. The book covers all aspects of microarray bioinformatics, giving you the tools to design arrays and experiments, to analyze your data, and to share your results with your organisation or with the international community. There are chapters covering sequence databases, oligonucleotide design, experimental design, image processing, normalisation, identifying differentially expressed genes, clustering, classification and data standards. The book is based on the highly successful Microarray Bioinformatics course at Oxford University, and therefore is ideally suited for teaching the subject at postgraduate or professional level.
Автор: Stafford Название: Methods in Microarray Normalization ISBN: 1420052780 ISBN-13(EAN): 9781420052787 Издательство: Taylor&Francis Рейтинг: Цена: 9123 р. Наличие на складе: Поставка под заказ.
Описание: This organized text compiles, for the first time, the most useful normalization methods developed for interpreting microarray data. Experts examine the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. They also review modern software, including discussions on key algorithms, comparative data, and download locations. The book contains the latest microarray innovations from companies such as Agilent, Affymetrix, and GeneGo as well as new, readily adaptable normalization methods for expression and CGH arrays. It also lists of open-source molecular profiling normalization algorithms available and where to access them.
Описание: The last few years have seen an unprecedented drive toward the application of proteomics to resolving challenging biomedical and biochemical tasks. Separation techniques combined with modern mass spectrometry are playing a central role in this drive. This book discusses the increasingly important role of mass spectrometry in proteomic research, and emphasizes recent advances in the existing technology and describes the advantages and pitfalls as well. Provides a scientifically valid method for analyzing the approximatey 500,000 proteins that are encoded in the human genome Explains the hows and whys of using mass spectrometry in proteomic analysis Brings together the latest approaches combining separation techniques and mass spectrometry and their application in proteome analysis Comments on future challenges and how they may be addressed Includes sections on troubleshooting
Описание: The emergence of genomics, the study of genes, is one of the major scientific revolutions of this century. Microarrays, a method used to analyze numerous DNA samples rapidly, enables scientists to make sense of this mountain of data using statistical analysis. They are being used in such areas of biomedical research as studying patterns for gene activity that cause cancers tpread. This book presents a comprehensive methodology for analyzing DNA microarray and protein array data. The most comprehensive treatment of this important emerging field, Exploration and Analysis of DNA Microarray and Protein Array Data includes: A review of basic molecular biology and a chapter introducing microarrays and their preparation Chapters on processing scanned images, preprocessing microarray data, group comparative experiments, and other designs Discussions of clustering, protein arrays, and applications for diagnostic tools Ample exercises assist absorbtion
Описание: The text provides an introduction to microarray technology, then moving on to image analysis, data analysis, cluster analysis, and beyond. With all chapters rewritten, updated, and expanded to include the latest generation of technology and methods, Guide to Analysis of DNA Microarray Data, Second Edition offers practitioners reliable information using concrete examples and a clear, comprehensible style. This Second Edition features entirely new chapters on: Image analysis Integrated analysis, and systems biology Experiment design Interpretation of results Automated analysis, Intended for readers seeking practical applications, this text covers a broad spectrum of proven approaches in this rapidly growing technology. Additional features include further reading suggestions for each chapter, as well as a thorough review of available analysis software.
Автор: Causton Helen, Barold S. Serge, Quackenbush John, Название: Microarray Gene Expression Data Analysis ISBN: 1405106824 ISBN-13(EAN): 9781405106825 Издательство: Wiley Рейтинг: Цена: 8720 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Microarrays are an automated way of carrying out thousands of experiments at once, allowing scientists to obtain huge amounts of information very quickly. This book provides a concise introduction to this difficult topic.
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