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Erythrocyte Engineering for Drug Delivery and Targeting, Magnani Mauro



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Автор: Magnani Mauro
Название:  Erythrocyte Engineering for Drug Delivery and Targeting
Перевод названия: Мауро Магнани: Выращивание эритроцитов для индустрии фармацевтики
ISBN: 9780306476914
Издательство: Springer
Классификация:
ISBN-10: 0306476916
Обложка/Формат: Hardback
Страницы: 148
Вес: 0.91 кг.
Дата издания: 01.01.2003
Серия: Biotechnology Intelligence Unit
Язык: English
Издание: Illustrated ed
Иллюстрации: Illustrations
Размер: 23.65 x 16.10 x 1.98
Читательская аудитория: Postgraduate, research & scholarly
Ссылка на Издательство: Link
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Поставляется из: Германии
Дополнительное описание: Язык: eng
Издание: Illustrated Edition
Оглавление: Red Blood Cell Loading: A Selection of Procedures; L. Rossi, S. Serafini, M. Magnani. Towards Activated Release of Payloads from Carrier Erythrocytes; A.M. Rollan, A.P. McHale. Targeting Drug Loaded Red Blood Cells; M. Magnani, L. Rossi, G. Brandi. Streptavidin-Mediated Coupling of Therapeutic Proteins to Carrier Erythrocytes; V.R. Muzykantov, J.-C. Murciano. Vaccination Strategy Using Red Blood Cells as Antigen Delivery System; L. Chiarantini. Engineered Nanoerythrocytes as a Novel Drug Delivery System; S. Jain, N.K. Jain. Red Blood Cells as Carriers of Antiviral Agents; A. Fraternale, A. Casabianca, M. Magnani. Erythrocytes as Carriers of Anthracycline Antibiotics in vitro and in vivo; V.M. Vitviksky. Drug-Loaded Red Blood Cells for the Control of the Inflammatory Response: Selective Targeting of Nuclear Factor-kB (NF-kB); R. Crinelli, A. Antonelli, M. Bianchi, L. Gentilini, M. Magnani. Design and Synthesis of New Pro-Drugs to be Used with Carrier Red Blood Cells; S. Scarfi, G. Damonte, U. Benatti. Engineered Red Blood Cells as Circulating Bioreactors; P. Ninfalli, E. Biagiotti.





Drug delivery and targeting for pharmacists and pharmaceutical scientists

Название: Drug delivery and targeting for pharmacists and pharmaceutical scientists
ISBN: 0415271983 ISBN-13(EAN): 9780415271981
Издательство: Taylor&Francis
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Цена: 7836 р.
Наличие на складе: Поставка под заказ.

Описание: An accessible and easy-to-read text, this is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications, and potential future developments, making it indispensable for pharmaceutical students, scientists and researchers. It covers how to optimize therapeutic efficacy; drug absorption, unwanted distribution and premature inactivation / elimination; attempts to minimize toxicity or alter immunogenicity; achieving rate-controlled drug release and effective drug targeting; routes of delivery; and technologies such as biosensors, microchips, stimuli-sensitive hydrogels, and plasmid-based gene therapy.

Allosteric Receptor Modulation In Drug Targeting

Автор: Bowery Norman G
Название: Allosteric Receptor Modulation In Drug Targeting
ISBN: 0824727916 ISBN-13(EAN): 9780824727918
Издательство: Informa
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Цена: 38803 р.
Наличие на складе: Нет в наличии.

Описание: Offering a wide array of illustrations and tables in every chapter, this book extensively covers the principles of allosterism in reference to drug action and progresses to a detailed examination of individual ionotropic and G-protein coupled receptor systems-helping those new to the subject understand the importance of allosterism and providing those already working in the field with specific reference information. This title provides in-depth chapters on basic principles of allosterism and its significance at GABAA, 5HT3, nicotinic, and GABAB receptors, ionotropic and metabotropic receptors for glutamate, muscarinic receptors and alpha 2 adrenoceptors to provide a firm foundation to the subject.

Multistate GTPase Control Co-translational Protein Targeting

Автор: Zhang
Название: Multistate GTPase Control Co-translational Protein Targeting
ISBN: 1441978070 ISBN-13(EAN): 9781441978073
Издательство: Springer
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Цена: 12704 р.
Наличие на складе: Поставка под заказ.

Описание: Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding of various biological processes. This dissertation comprehensively demonstrates how two universally conserved guanosine triphosphatases in the signal recognition particle and its membrane receptor maintain the efficiency and fidelity of the co-translational protein targeting process essential to all cells. A series of quantitative experiments reveal that the highly ordered and coordinated conformational states of the machinery are the key to their regulatory function. This dissertation also offers a mechanistic view of another fascinating system in which multistate protein machinery closely control critical biological processes.Written while completing graduate work at California Institute of Technology.

Antigen Delivery Systems: Immunological And Technological Issues (Drug Targeting & Delivery)

Автор: Gander Bruno
Название: Antigen Delivery Systems: Immunological And Technological Issues (Drug Targeting & Delivery)
ISBN: 9057022672 ISBN-13(EAN): 9789057022678
Издательство: Informa
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Цена: 20771 р.
Наличие на складе: Нет в наличии.

Описание: This text presents an up-to-date overview of recent developments in this field, reviews new trends in vaccine development programs, and emphasizes the requirements and importance of varied vaccine delivery systems.

Nanotechnology-Based Approaches for Targeting and Delivery of Dru

Автор: Mishra, Vijay
Название: Nanotechnology-Based Approaches for Targeting and Delivery of Dru
ISBN: 0128097175 ISBN-13(EAN): 9780128097175
Издательство: Elsevier Science
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Цена: 10967 р.
Наличие на складе: Поставка под заказ.

Описание: Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes provides an overview of the important aspects of nanomedicine in order to illustrate how to design and develop novel and effective drug delivery systems using nanotechnology. . The book is organized into three sections, beginning with an introduction to nanomedicine and its associated issues. Section two discusses the latest technologies in nanomedicine, while the third section covers future developments and challenges in the field. . By focusing on the design, synthesis, and application of a variety of nanocarriers in drug and gene delivery, this book provides pharmaceutical and materials science students, professors, clinical researchers, and industry scientists with a valuable resource aimed at tackling the challenges of delivering drugs and genes in a more targeted manner.

Drug Targeting / Strategies, Principles, and Applications

Автор: Francis G. E.
Название: Drug Targeting / Strategies, Principles, and Applications
ISBN: 089603531X ISBN-13(EAN): 9780896035317
Издательство: Springer
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Цена: 16746 р.
Наличие на складе: Поставка под заказ.

Описание: G. E. Francis and Cristina Delgado have assembled a comprehensive collection of leading-edge protocols for drug targeting studies. In addition to the detailed step-by-step instruction, the protocols review the principal current targeting strategies, discuss how to build the constructs, examine theoretical considerations relevant to solid tumors, and describe experimental and clinical applications of targeted drug delivery systems. Also present are new chemical and biological approaches to the preparation of targeted biopharmaceuticals, including ribonuclease-antibody chimeras, bispecific antibodies, enzyme-antibody conjugates, and folate-bearing conjugates. Applications include the targeting of myocardial infarctions using liposomal systems, the use of monoclonal antibodies to target malaria and HIV-infected cells, the targeting of fusion proteins to leukemias and lymphomas, and the use of antioxidant enzyme-antibody conjugates to target the pulmonary endothelium. Comprehensive and innovative, Drug Targeting: Strategies, Principles, and Applications documents in practical detail the major new chemical and biological targeting methods now being used to produce today's emerging rich array of novel diagnostic agents and promising biopharmaceuticals.

Biomedical Aspects of Drug Targeting

Автор: Muzykantov Vladimir R., Torchilin Vladimir P.
Название: Biomedical Aspects of Drug Targeting
ISBN: 1402072325 ISBN-13(EAN): 9781402072321
Издательство: Springer
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Цена: 26450 р.
Наличие на складе: Поставка под заказ.

Описание: This book includes general principles of drug targeting, targeting in the cardiovascular system, tumor targeting, brain targeting, miscellaneous targeting and novel approaches for targeting (new horizons). It is designed in a course-like fashion: from more general and simple to more specific and complex material. This framework will help even unfamiliar readers to learn new topics and navigate in the text. Although the book is aimed primarily at industrial and academic pharmacologists and drug discovery researchers, its design will make the book useful for advanced level graduate students. The book focuses on ligand-mediated drug targeting strategies, with additional chapters on general aspects of drug delivery that are of paramount importance in drug targeting (biological barriers, stealth technologies). Included are topics on targeting of genetic materials important in the biomedical context of the ligand-mediated targeting.

GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions

Автор: Gilchrist
Название: GPCR Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions
ISBN: 0470307781 ISBN-13(EAN): 9780470307786
Издательство: Wiley
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Цена: 19800 р.
Наличие на складе: Поставка под заказ.

Описание: The fundamental guide on the basic concepts and medical significance of GPCRs The focus of this book, G protein-coupled receptors (GPCRs) are a large protein family of transmembrane proteins that sense molecules outside the cell and relay the informati

Drug and Enzyme Targeting, Part A,112

Автор: Nathan P. Colowick
Название: Drug and Enzyme Targeting, Part A,112
ISBN: 0121820122 ISBN-13(EAN): 9780121820121
Издательство: Elsevier Science
Рейтинг:
Цена: 6347 р.
Наличие на складе: Поставка под заказ.

Targeting Protein Kinases for Cancer Therapy

Автор: Matthews
Название: Targeting Protein Kinases for Cancer Therapy
ISBN: 0470229659 ISBN-13(EAN): 9780470229651
Издательство: Wiley
Рейтинг:
Цена: 17463 р.
Наличие на складе: Поставка под заказ.

Описание: An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have t

Protein Targeting.1996

Автор: Hurtley
Название: Protein Targeting.1996
ISBN: 0199635617 ISBN-13(EAN): 9780199635610
Издательство: Oxford Academ
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Цена: 11641 р.
Наличие на складе: Поставка под заказ.

Описание: Protein targeting is the study of how proteins synthesized in one part of the cell reach their ultimate destination. This book is a preview of the latest research, which has applications for understanding cancer, studying diseases due to faulty targeting, and genetic manipulation of microorganisms.

Targeting Functional Centers of the Ribosome

Автор: Davidovich
Название: Targeting Functional Centers of the Ribosome
ISBN: 3642169309 ISBN-13(EAN): 9783642169304
Издательство: Springer
Рейтинг:
Цена: 10047 р.
Наличие на складе: Поставка под заказ.

Описание: This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.


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