Osteoimmunology / Interactions of the Immune and Skeletal Systems, Choi Yongwon
Автор: Abul K. Abbass, Andrew H. H. Lichtman, Shiv Pillai Название: Basic Immunology, Functions and Disorders of the Immune System, 5th Edition ISBN: 032339082X ISBN-13(EAN): 9780323390828 Издательство: Elsevier Science Рейтинг: Цена: 4989 р. 6236.00-20% Наличие на складе: Есть (1 шт.) Описание: In this updated edition of Basic Immunology, the authors continue to deliver a clear, modern introduction to immunology, making this the obvious choice for today's busy students. Their experience as teachers, course directors, and lecturers helps them to distill the core information required to understand this complex field. Through the use of high-quality illustrations, relevant clinical cases, and concise, focused text, it's a perfectly accessible introduction to the workings of the human immune system.
Автор: Tak W. Mak Название: Primer to The Immune Response, ISBN: 0123852455 ISBN-13(EAN): 9780123852458 Издательство: Elsevier Science Рейтинг: Цена: 9119 р. Наличие на складе: Поставка под заказ.
Описание: Written in the same engaging conversational style as the acclaimed first edition, Primer to The Immune Response, 2ndEdition is a fully updated and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction to immunology. The authors bring clarity and readability to their audience, offering a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subject’s fascinating appeal. The content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. The superbly drawn figures are now in full color, complemented by full color plates throughout the book. The text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights. At the end of each chapter, a self-test quiz allows students to monitor their mastery of major concepts, while a set of conceptual questions prompts them to extrapolate further and extend their critical thinking. Moreover, as part of the Academic Cell line of textbooks, Primer to The Immune Response, 2nd Edition contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles also form the basis of case studies that are found in the associated online study guide and are designed to reinforce clinical connections.
Описание: This volume comprises the most up-to-date account of existing knowledge on the subject of cardiomyopathy and heart failure. Its multidisciplinary approach covers cardiovascular medicine; biochemistry; immunology; molecular biology; virology; epidemiology; and clinical medicine. Cardiomyopathies and Heart Failure: -Covers all major investigational and clinical aspects of the topic; -Provides syntheses as well as reviews; -Offers a unique multidisciplinary and international perspective; -Includes an extensive list of references to relevant work; -Targeted towards practicing physicians and basic researchers.
Описание: This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the Methods in Pharmacology and Toxicology series, the book includes the kind of detail and implementation advice to encourage success in the lab.
Authoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital background on epigenetics and state-of-the-art techniques in epigenomics.
Автор: Monie, Tomi Название: The Innate Immune System ISBN: 0128044640 ISBN-13(EAN): 9780128044643 Издательство: Elsevier Science Рейтинг: Цена: 10158 р. Наличие на складе: Поставка под заказ.
Описание: The Innate Immune System: A Compositional and Functional Perspective focuses on the components and functionality of the innate immune system, detailing how they work in their own right, and then progressing to cover their relevance to disease and how they interface with the adaptive response. Despite the growing appreciation of the importance of the innate immune system, many classical immunology books still focus predominantly on the adaptive immune response. Not only is this unbalanced, but it fails to reflect the growing synergy between the activation and function of the innate response and the final nature of adaptive response. This book fills the gap in knowledge that is needed to fully understand and appreciate the topic.
Описание: Artificial Immune Systems (AIS) are adaptive systems inspired by the biological immune system and applied to problem solving. This book provides an accessible introduction that will be suitable for anyone who is beginning to study or work in this area. It gives a clear definition of an AIS, sets out the foundations of the topic (including basic algorithms), and analyses how the immune system relates to other biological systems and processes. No prior knowledge of immunology is needed - all the essential background information is covered in the introductory chapters.Key features of the book include:- A discussion of AIS in the context of Computational Intelligence;- Case studies in Autonomous Navigation, Computer Network Security, Job-Shop Scheduling and Data Analysis =B7 An extensive survey of applications;- A framework to help the reader design and understand AIS;- A web site with additional resources including pseudocodes for immune algorithms, and links to related sites.Written primarily for final year undergraduate and postgraduate students studying Artificial Intelligence, Evolutionary and Biologically Inspired Computing, this book will also be of interest to industrial and academic researchers working in related areas.
Автор: Wilce, James M. Название: Social and Cultural Lives of Immune Systems ISBN: 0415310059 ISBN-13(EAN): 9780415310055 Издательство: Taylor&Francis Рейтинг: Цена: 7286 р. Наличие на складе: Поставка под заказ.
Описание: Social and Cultural Lives of Immune Systems introduces a provocative new hypothesis in medico-social theory - the theory that immunity and disease are in
part socially constituted, and that immune systems function not just as biological entities but also as symbolic concepts charged with political significance. Bridging elements of
psychology, sociology, body theory, immunology and medical anthropology, twelve papers from leading scholars explicate some of the health-hazards of emotional and social pressure,
whilst analysing the semiotic and social responses to the imagery of immunity. Is it possible, as some experts now claim, that the terminology of immunity, dependent upon the defense of
the self from the invasion by an alian other, has entered modern consciousness to a point where it serves as a metaphor and indicator of wider political strategy? Can immunological
rhetoric genuinely be shown to affect military operations, crime policy and international food distribution?If this is the case, what conclusions can be drawn from the fact that tactics of
disclosure, emotional openness and inclusion are clinically proven to boost immunity, whereas division, denial and containment - apparently modelled on the activities of immune cells -
ironically raise susceptibility to disease? Possibly the first cultural analysis of embodiment to give close attention to immune function, and certainly one of the first studies of immunology,
disease and healing to look seriously at concepts of the social self, it offers a comprehensive framework for future study in a
exciting new area.
James Wilce, Roger Booth, Kathryn Davison, Seamus Decker, Barry England, Mark Flinn, Laurence J Kirmayer, Margot Lyon, Samuel J. Mann, Emily
Martin, Thom McDade, Daniel Moerman, David Napier, James Pe
Описание: This volume will review the most recent advances in the understanding of cellular and molecular mechanisms for immune responses and immune regulation. Chapters in the first portion of this book will discuss the theoretical basis for current immunotherapies for autoimmune diseases. The second portion of the book will provide an updated review on the research behind the clinical trials/immunotherapies (e.g. T-cell vaccination, antibody therapy, etc.) in the areas of autoimmune diseases by the principal investigators of these studies. These chapters will discuss clinical and basic research as well as immunological data in the context of cellular and molecular mechanisms of the therapies. The book will finish with chapters by leaders in the field who will provide expert views on challenges and future directions.
Описание: Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Описание: During the past five years major progress has been made in understanding the basic mechanisms of lymphocyte homeostasis and in the developmental relationship between different memory T subsets and their traffic patterns and functional significance. This volume highlights the current concepts of lymphocyte development, factors regulating lymphocyte trafficking and development, and specialized characteristics and functional properties of naive and memory subsets. This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III. This includes tracking of dendritic cells in vivo, monitoring arterial smooth muscle-specific T cells in the inflamed vasculature, imaging of molecular migrations in immune synapses, and visualization of various immune cells in intact lymphoid tissues by two photon confocal imaging. This volume should be of interest to immunologists, molecular biologists, microbiologists, pathologists, academic physicians, cell biologists, and scientists and clinicians interested in vaccine development.
Описание: Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies. This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.
Автор: Diana Boraschi Название: Immune Rebalancing: The Future of Immunosuppression ISBN: 0128033029 ISBN-13(EAN): 9780128033029 Издательство: Elsevier Science Рейтинг: Цена: 8310 р. Наличие на складе: Поставка под заказ.
Описание:
Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine.
Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc.
Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes
Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections
Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches
Provides information on the new strategies for drug development in this field
Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations
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