Описание: Written by a leader in the field, "Analytical Methods in Combinatorial Chemistry" is the first comprehensive review of analytical methods in this field, with a focus
on combinatorial drug discovery. The second edition updates the first with close to 50 per cent new material and a detailed discussion of new developments in analytical methods,
technologies, and applications in combinatorial chemistry in the past three years. The book also includes new chapters on high-throughput purification and the application of
combinatorial chemistry in materials science and cataly
It focuses on new drug candidates and drugs developed through combinatorial chemistry.
Описание: Quality measurement, control, and improvement in combinatorial chemistry Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable." To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. A new volume in Wiley's Chemical Analysis series, this text has four parts covering: Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis High-throughput analytical methods used to analyze the quality of libraries High-throughput purification techniques Analytical methods applied in post-synthesis and post-purification stages Drawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (KC) technologies, as well as other analytical techniques. This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.
Описание: This volume describes advances in the design, research, development, and application of environmental chemical sensors and biosensors. Topics include the rational assembly of dynamic macromolecules, biocomponent stability, DNA based biosensors and molecular beacons.
Описание: Part of a series on Integrated Microanalytical Systems, this book discusses the applications of photonic technologies in bio-chemical sensing. Based on photonic structures, it is divided into 4 sections: Photonic crystal structures; Optical microring resonator structures; Optical fiber/waveguide structures; and, Miscellaneous or hybrid structures.
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