Drug Resistance in the Treatment of Cancer, Herbert M. Pinedo
Автор: Bristow Название: Early Diagnosis and Treatment of Cancer Series: Ovarian Cancer: Expert Consult: Online and Print ISBN: 1416046852 ISBN-13(EAN): 9781416046851 Издательство: Elsevier Science Рейтинг: Цена: 13102.00 р. 18717.00-30% Наличие на складе: Есть (1 шт.) Описание: Packed with practical information designed to cover the range of diagnostic procedures, including pathologic, radiologic, bronchoscopic, and surgical aspects, this title helps you to determine the safest, shortest, least invasive way to reach an accurate diagnosis; stage the disease; and, choose the best initial treatment for early stages.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Pinedo Название: Drug Resistance in the Treatment of Cancer ISBN: 0521473217 ISBN-13(EAN): 9780521473217 Издательство: Cambridge Academ Рейтинг: Цена: 26136.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reviews the mechanisms and clinical implications of drug resistance in cancer, considered to be the most significant obstacle to the cure of cancer today. Topics covered include multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and haematopoietic support.
Название: Multi-drug resistance in cancer ISBN: 1607614154 ISBN-13(EAN): 9781607614159 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The efficacy of chemotherapeutic management of cancer is often severely limited. This book provides comprehensive reviews of multidrug resistance mechanisms. It includes up-to-date techniques for detection and imaging of drug transporters.
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