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Human Mitochondrial DNA and the Evolution of Homo sapiens, Bandelt



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Цена: 19532р.
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Автор: Bandelt
Название:  Human Mitochondrial DNA and the Evolution of Homo sapiens
Издательство: Springer
Классификация:
Социология и социальные исследования
Биологические науки: общие вопросы
Биология человека и связанные с ним разделы

ISBN: 3540317880
ISBN-13(EAN): 9783540317883
ISBN: 3-540-31788-0
ISBN-13(EAN): 978-3-540-31788-3
Обложка/Формат: Hardback
Страницы: 271
Вес: 0.724 кг.
Дата издания: 12/05/2006
Серия: Human Genetics / Nucleic Acids and Molecular Biology
Язык: English
Иллюстрации: 10 black & white tables, biography
Размер: 24.23 x 15.95 x 1.96
Читательская аудитория: Undergraduate
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: Mitochondrial DNA is one of the most explored genetic systems because of what it can tell us about the human past. This volume takes a unique perspective, presenting the disparate strands that must be tied together to exploit this system. From molecular biology to anthropolo y, statistics to ancient DNA, this first volume of three presents the global picture of human mitochondrial DNA variation.

It takes a critical look at the field, flagging the problems, as well as the successes, and always placing the mitochondrial phylogeny centre stage.




Human Mitochondrial DNA and the Evolution of Homo sapiens

Автор: Hans-J?rgen Bandelt; Martin Richards; Vincent Maca
Название: Human Mitochondrial DNA and the Evolution of Homo sapiens
ISBN: 3642068685 ISBN-13(EAN): 9783642068683
Издательство: Springer
Рейтинг:
Цена: 19531 р.
Наличие на складе: Нет в наличии.

Описание: Mitochondrial DNA is one of the most closely explored genetic systems, because it can tell us so much about the human past. From molecular biology to anthropology, statistics to ancient DNA, this first volume of three presents a comprehensive global picture and a critical appraisal of human mitochondrial DNA variation.

Mitochondrial Dysfunction in Neurodegenerative Disorders

Автор: Reeve
Название: Mitochondrial Dysfunction in Neurodegenerative Disorders
ISBN: 0857297007 ISBN-13(EAN): 9780857297006
Издательство: Springer
Рейтинг:
Цена: 14625 р.
Наличие на складе: Нет в наличии.

Описание: As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in which mitochondrial dysfunction contributes to the pathogenesis of these diseases, guiding the reader through the basic functions of mitochondria and the mechanisms that lead to their dysfunction, to the consequences of this dysfunction on neuronal function before finishing with the modelling of these disorders and discussion of new potential therapeutic targets. Mitochondrial Dysfunction in Neurodegenerative Disorders provides an accessible, authoritative guide to this important area for neurologists; research and clinical neuroscientists; neuropathologists; and residents with an interest in clinical research.

The Speciation of Modern Homo Sapiens

Название: The Speciation of Modern Homo Sapiens
ISBN: 0197262465 ISBN-13(EAN): 9780197262467
Издательство: Oxford Academ
Цена: 3394 р.
Наличие на складе: Нет в наличии.

Описание: Addresses the question of the speciation of modern Homo sapiens. The subject raises profound questions about the nature of the species, our defining characteristic (it is suggested it is language), and the brain changes and their genetic basis that make us distinct.

Gmo Sapiens: The Life-Changing Science of Designer Babies

Автор: Knoepfler Paul
Название: Gmo Sapiens: The Life-Changing Science of Designer Babies
ISBN: 9814678538 ISBN-13(EAN): 9789814678537
Издательство: World Scientific Publishing
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Цена: 3087 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book won the INDIEFAB 2015 Bronze Award for Science (Adult nonfiction).Genetically modified organisms (GMOs) including plants and the foods made from them, are a hot topic of debate today, but soon related technology could go much further and literally change what it means to be human. Scientists are on the verge of being able to create people who are GMOs.Should they do it? Could we become a healthier and 'better' species or might eugenics go viral leading to a real, new world of genetic dystopia? GMO Sapiens tackles such questions by taking a fresh look at the cutting-edge biotech discoveries that have made genetically modified people possible.Bioengineering, genomics, synthetic biology, and stem cells are changing sci-fi into reality before our eyes. This book will capture your imagination with its clear, approachable writing style. It will draw you into the fascinating discussion of the life-changing science of human genetic modification.

Gmo Sapiens: The Life-Changing Science of Designer Babies

Автор: Knoepfler Paul
Название: Gmo Sapiens: The Life-Changing Science of Designer Babies
ISBN: 9814667005 ISBN-13(EAN): 9789814667005
Издательство: World Scientific Publishing
Рейтинг:
Цена: от 6049 р.
Наличие на складе: Есть

Описание: This book won the INDIEFAB 2015 Bronze Award for Science (Adult nonfiction).Genetically modified organisms (GMOs) including plants and the foods made from them, are a hot topic of debate today, but soon related technology could go much further and literally change what it means to be human. Scientists are on the verge of being able to create people who are GMOs.Should they do it? Could we become a healthier and 'better' species or might eugenics go viral leading to a real, new world of genetic dystopia? GMO Sapiens tackles such questions by taking a fresh look at the cutting-edge biotech discoveries that have made genetically modified people possible.Bioengineering, genomics, synthetic biology, and stem cells are changing sci-fi into reality before our eyes. This book will capture your imagination with its clear, approachable writing style. It will draw you into the fascinating discussion of the life-changing science of human genetic modification.

Mitochondrial Genome Evolution,63

Автор: Laurence Marechal-Drouard
Название: Mitochondrial Genome Evolution,63
ISBN: 0123942799 ISBN-13(EAN): 9780123942791
Издательство: Elsevier Science
Рейтинг:
Цена: 17243 р.
Наличие на складе: Нет в наличии.

Описание: Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences.Features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. Thisthematic volume features reviews on Mitochondrial genome evolution.

Mitochondrial DNA, Mitochondria, Disease and Stem Cells

Автор: St. John
Название: Mitochondrial DNA, Mitochondria, Disease and Stem Cells
ISBN: 1627031006 ISBN-13(EAN): 9781627031004
Издательство: Springer
Рейтинг:
Цена: 16719 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease. It also highlights the importance of the mitochondrial assembly factors and how mutations to these can lead to mitochondrial disease. The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional mitochondria. Finally, it draws on assisted reproductive technologies to discuss how some of these approaches might be adapted to prevent the transmission of mutant and deleted mtDNA from one generation to the next.

Mitochondrial Dynamics and Neurodegeneration

Автор: Lu
Название: Mitochondrial Dynamics and Neurodegeneration
ISBN: 9400712901 ISBN-13(EAN): 9789400712904
Издательство: Springer
Рейтинг:
Цена: 19532 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.

Mitochondrial Dysfunction in Neurodegenerative Disorders

Автор: Reeve
Название: Mitochondrial Dysfunction in Neurodegenerative Disorders
ISBN: 3319286358 ISBN-13(EAN): 9783319286358
Издательство: Springer
Рейтинг:
Цена: 14106 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This second edition brings together up-to-date contributionsfrom leaders in the field internationally on the various ways in whichmitochondrial dysfunction contributes to the pathogenesis of neurodegenerativediseases, including Parkinson’s disease, Alzheimer’s disease and multiplesclerosis. The reader is guided through the basic functions of mitochondria andthe mechanisms that lead to their dysfunction, and on to the consequences ofthis dysfunction for neuronal function before finishing with the modelling ofthese disorders and discussion of new potential therapeutic targets. Additional chapters have been added to the book to reflectadvances in the field and there are many new contributors and topics, includinghow mitochondria are degraded and the interaction of the mitochondria withpathologically relevant proteins. Mitochondrial Dysfunction in Neurodegenerative Disordersprovides an accessible, authoritative guide to this important area forneurologists; research and clinical neuroscientists; neuropathologists; andresidents with an interest in clinical research.

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson`s Disease

Автор: Buhlman
Название: Mitochondrial Mechanisms of Degeneration and Repair in Parkinson`s Disease
ISBN: 3319421379 ISBN-13(EAN): 9783319421377
Издательство: Springer
Рейтинг:
Цена: 16602 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson’s etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson’s disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson’s disease, efforts to postpone, prevent and “cure” onset mitochondrial aberrations and neurodegeneration associated with Parkinson’s disease in various models are encouraging. While only about ten percent of Parkinson’s patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson’s disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.

How Homo Became Sapiens

Автор: G„rdenfors, Peter
Название: How Homo Became Sapiens
ISBN: 0198528515 ISBN-13(EAN): 9780198528517
Издательство: Oxford Academ
Рейтинг:
Цена: 6327 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In this entertaining work, Peter G„rdenfors embarks on an evolutionary detective story to try and solve one of the big mysteries surrounding human existence - how has the modern human being's way of thinking come into existence. Immensely readable and full of humorous insights, the book will be valuable for students in psychology and biology, and accessible to readers of popular science.

The Speciation of Modern Homo Sapiens

Автор: Crow, T. J.
Название: The Speciation of Modern Homo Sapiens
ISBN: 0197263119 ISBN-13(EAN): 9780197263112
Издательство: Oxford Academ
Рейтинг:
Цена: 2876 р.
Наличие на складе: Невозможна поставка.

Описание: This is the first volume to address directly the question of the speciation of modern Homo sapiens. The subject raises profound questions about the nature of the species, our defining characteristic (it is suggested it is language), and the brain changes and their genetic basis that make us distinct. The British Academy and the Academy of Medical Sciences have brought together experts from palaeontology, archaeology, linguistics, psychology, genetics and evolutionary theory to present evidence and theories at the cutting edge of our understanding of these issues. These essays will be vital reading for anyone interested in the nature and origins of the species, and specifically human abilities.


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