Автор: Abbas, Abul K. Fausto, Nelson Kumar, Vinay Название: Robbins and Cotran Pathologic Basis of Disease.-9 ed. ISBN: 0808924508 ISBN-13(EAN): 9780808924500 Издательство: Elsevier Science Рейтинг: Цена: 9136.00 р. Наличие на складе: Поставка под заказ.
Описание: Ashton B. Carter said when announcing that the Pentagon would open all combat jobs to women, "I made a commitment to building America`s force of the future. In the twenty-first century, that requires drawing strength from the broadest possible pool of talent." William Taylor chronicles and analyses the long and ever-changing history of that often contentious and controversial effort.
Автор: Rudolph Название: Alzheimer`s Disease ISBN: 1439827087 ISBN-13(EAN): 9781439827086 Издательство: Taylor&Francis Рейтинг: Цена: 17149.00 р. 24499.00-30% Наличие на складе: Есть (1 шт.) Описание:
In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer's disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer's Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD.
With contributions from experts drawn from academia, clinical practice, and the biotechnology and pharmaceutical industries, the book explores:
The basis of AD and the role of Aβ oligomers in development of disease
Existing and emerging in vitro biomarker-based methodologies for the diagnosis of AD, focusing on genetic, biochemical, and conformational strategies
In vivo imaging diagnostic approaches
Evolving diagnostic criteria, health regulatory guidelines, biomarkers in clinical trials, and available and emerging therapies
Recent progress in small-molecule disease-modifier drug discovery efforts for AD, specifically in the areas of Aβ, tau, and emerging neuroprotective/neurorepair approaches
How a case study of AD raises issues regarding clinical and pathologic criteria, risk factors, and the amyloid hypothesis
The molecular conformational factors that govern the pathogenicity of aggregating proteins, and how these factors could represent new targets for disease-modifying therapies
The latest epidemiological, pathological, biochemical, and behavioral studies that may shed some light on the risk of developing AD and similar dementias after traumatic brain injury
Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases.
Overall, this is an excellent book on infectious conditions and diseases in the central nervous system, including their accurate diagnosis, understanding, and surgical and nonsurgical treatment and management. -- BIZ INDIA
The two editors have succeeded in producing a great reference on all aspects of neurosurgical infections. This is a well-written, comprehensive review of a difficult topic. -- Doody Enterprises, Inc.
Rapid diagnosis and treatment are crucial to successful outcomes in infections involving the central nervous system, which can cause significant neurological morbidity and mortality. Neurosurgical Infectious Disease: Surgical and Nonsurgical Management is a comprehensive guide that gives surgeons the core knowledge they need to diagnose, treat, and prevent infectious diseases of the central nervous system.
Key Features:
Emphasizes newer surgical techniques, including: endoscopy, neuronavigation, and intraoperative guidance
Covers contemporary radiologic diagnostic techniques and provides excellent imaging examples
Includes chapters on antibiotic prophylaxis, intracranial infection, and the infection of implanted devices
This excellent neurosurgical reference will be an essential part of the armamentarium used by neurosurgeons and infectious disease specialists in their daily practice.
Описание: Occupational and environmental health is the public health and multidisciplinary approach to the recognition, diagnosis, treatment, prevention, and control of disease, injuries, and other adverse health conditions resulting from hazardous environmental exposures in the workplace, the home, or the community. These are essential elements of public health practice and a core of the curriculum in the schools of public health. Thoroughly updated and expanded upon, the sixth edition of Occupational and Environmental Health provides comprehensive coverage and a clear understanding of occupational and environmental health and its relationships to public health, environmental science, and governmental policy. New chapters include Toxicology; The Roles of Government and International Organizations; and Risk Communication in Workplaces and Communities. The authors also expand on chapters included in previous chapters, and the book features practical case studies, numerous tables, graphs, and photos, and annotated bibliographies.
Автор: Rychik Jack Название: Fetal Cardiovascular Imaging: A Disease Based Approach ISBN: 1416031723 ISBN-13(EAN): 9781416031727 Издательство: Elsevier Science Рейтинг: Цена: 17854.00 р. Наличие на складе: Поставка под заказ.
Описание: A video atlas that provides visual guidance you need to successfully identify a range of fetal heart disorders. It guides the acquisition and interpretation of fetal images for accurate diagnosis and effective management.
Автор: Engleberg N. Cary, Dermody Terence, DiRita Victor Название: Schaechter`s mechanisms of microbial disease ISBN: 1451100051 ISBN-13(EAN): 9781451100051 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 10468.00 р. Наличие на складе: Поставка под заказ.
Описание: Schaechter's Mechanisms of Microbial Disease provides students with a thorough understanding of microbial agents and the pathophysiology of microbial diseases. The text is universally praised for "telling the story of a pathogen" in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms, rather than forcing students to memorize isolated facts by rote. The table of contents is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula. Case studies with problem-solving questions give students insight into clinical applications of microbiology, which is ideal for problem-based learning.
Автор: Lewin Mark B Название: Echocardiography in Congenital Heart Disease ISBN: 1437726968 ISBN-13(EAN): 9781437726961 Издательство: Elsevier Science Рейтинг: Цена: 14315.00 р. Наличие на складе: Поставка под заказ.
Описание: Provides practical how-to-do-it guidance on echocardiography for a number of pediatric and adult congenital heart disease patients. This title offers you a visual, case-based approach that facilitates understanding and equips you to accurately acquire and interpret images while avoiding pitfalls.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
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