Tumor Infiltrating B Lymphocytes: A Novel Approach for Cancer Diagnostics and Therapeutics, Beatrix Kotlan (Ed.)
Автор: Nakamura Название: Cancer Diagnostics. 2004 ISBN: 1588291677 ISBN-13(EAN): 9781588291677 Издательство: Springer Рейтинг: Цена: 26450 р. Наличие на складе: Поставка под заказ.
Описание: offers a review of the considerable advances in technology during the past several years; the authors were concerned primarily with clinical laboratory tests; these tests may already, or in the near future, help in the early detection, evaluation, and prediction of human tumors for specific therapeutic decisions.
Автор: George Patrinos Название: Molecular Diagnostics, ISBN: 0125466617 ISBN-13(EAN): 9780125466615 Издательство: Elsevier Science Рейтинг: Цена: 12821 р. Наличие на складе: Невозможна поставка.
Описание: "Molecular Diagnostics" covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by examples from the authors' own expertise. The contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage.
Описание: This updated and expanded tutorial guide to molecular diagnostic techniques takes advantage of many new molecular technologies to include both improved traditional methods and totally new methods, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity testing, as well as new insights into the question of quality assurance in the molecular diagnostics laboratory. Additional chapters address other technologies found in the clinical laboratory that complementary to molecular diagnostic technologies and discuss genetic counseling and the ethical and social issues involved with nucleic acid testing. A value-added compact disk containing a companion e-book version of the book, is included for downloading and use in the reader's PC or PDA.
Описание: Provides the guidance necessary to select, perform, and evaluate the results of established laboratory tests. This book attempts to bridge the gap between the clinical laboratory and medical management by relating pathophysiology to analytical results in health and disease. It also describes variables that affect tests and results.
Автор: Berke Gideon, Clark William R. Название: Killer Lymphocytes ISBN: 1402065639 ISBN-13(EAN): 9781402065637 Издательство: Springer Рейтинг: Цена: 10971 р. Наличие на складе: Поставка под заказ.
Описание: We have known about the existence of killer lymphocytes since 1960, when they were discovered in connection with transplant rejection in vivo. Since then we have uncovered at least five subsets of lymphocytes that can kill other cells in vitro, establishing the study of cell-mediated cytotoxicity (CMC) as a major field of immunological inquiry. Berke and Clark summarize the extensive literature based on the study of CMC in vitro. Several important questions about killer cells have now been answered, for example, how they go about destroying other cells. Research ultimately revealed at least three lytic mechanisms available to killer lymphocytes. But do killer cells actually use these mechanisms in vivo? The possible involvement of CMC in transplant rejection, control of intracellular parasites, cancer, autoimmunity, and immune homeostatic regulation is analyzed in detail, yielding some surprising findings, and outlining important questions that remain unanswered. This extensively documented, comprehensive survey of cell-mediated cytotoxicity traces the history of killer lymphocytes from 1960 to the present, providing a definitive resource for specialists and non-specialists alike.
Описание: Principles of Molecular Diagnostics and Personalized Cancer Medicine" The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care. Improve your understanding of… • The basic mechanisms of carcinogenesis— including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors. • The most current molecular techniques —including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing. • Molecular tests —including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment. • Imaging and screening technologies —including molecular imaging, genetic tests, biostatistics, and bioinformatics. • The molecular basis of therapy —including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. • Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management. • Targeted treatment – including personalized medicine and targeted therapy for commonly occurring malignancies— plus insights on new approaches to targeted drug discovery and the future of molecular oncology!
Описание: Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements of biosensors and their applications in detection and diagnostics. The book addresses cancer molecular diagnostics, including genomic and proteomic approaches, from the perspective of biosensors and biodetection. It explains how to measure and understand molecular markers using biosensors and discusses the medical advantages of rapid and accurate cancer diagnostics. It also describes optical, electrochemical, and optomechanical biosensor technologies, with a focus on cancer analysis and the clinical utility of these technologies for cancer detection, diagnostics, prognostics, and treatment. Making biosensor technology more accessible to molecular biologists, oncologists, pathologists, and engineers, this volume advances the integration of this technology into mainstream clinical practice. Through its in-depth coverage of a range of biosensors, the book shows how they can play instrumental roles in the early molecular diagnosis of cancer.
Автор: Knudsen, Steen Название: Cancer diagnostics with dna microarrays ISBN: 0471784079 ISBN-13(EAN): 9780471784074 Издательство: Wiley Рейтинг: Цена: 22275 р. Наличие на складе: Поставка под заказ.
Описание: Acts as a reference work on the use of DNA microarray data in the diagnosis of and treatment planning for human cancers. This book deals with clinical application of microarray data to oncology diagnosis, leading to diagnosis of and treatment regimens for various human cancers. It also offers a summary presentation of the DNA microarrays.
Описание: The book provides a comprehensive compilation of fundamentals, technical solutions and applications for medical imaging systems. It is intended as a handbook for students in biomedical engineering, for medical physicists, and for engineers working on medical technologies, as well as for lecturers at universities and engineering schools.
Описание: This ready reference discusses different methods for statistically analyzing and validating data created with high-throughput methods. As opposed to other titles, this book focusses on systems approaches, meaning that no single gene or protein forms the
Автор: George Patrinos Название: Molecular Diagnostics, ISBN: 0123745373 ISBN-13(EAN): 9780123745378 Издательство: Elsevier Science Рейтинг: Цена: 13629 р. Наличие на складе: Поставка под заказ.
Описание: Key Features<br>. Contains state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders<br>. Includes in-depth discussion of ethical and safety considerations <br>. Identifies genetically modified organisms (GMO's)<br>. Covers forensic analysis and every-day issues in a diagnostic laboratory<br><br>Description<br>The second edition of Molecular Diagnostics, the only book dealing with diagnosis on a molecular level, discusses current molecular biological techniques used to identify the underlying molecular defects in inherited disease. The book delves further into the principle and brief description of the technique, followed by examples from the authors' own expertise. Contributors to the 2/e are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Molecular Diagnostics, 2/e , is a needed resource for graduate students, researchers, physicians and practicing scientists in molecular genetics; professionals from similar backgrounds working in diagnostic laboratories in academia or industry, as well as, academic institutions and hospital libraries.<br><br>RELATED TITLES:<br>Trent/Molecular Medicine, April 2005,$79.95, 0-12-699057-3 <br><br>Innis (1999) PCR Applications, HB, $89.95,0-12-372185-7, PB, $66.95, <br><br>Key Features:<br>*Deals exclusively with the currently used molecular biology techniques to identify the underlying molecular defect of inherited diseases<br><br>*Includes pharmacogenetics and pharmacogenomics relating to new cancer therapies<br><br>*Provies a comprehensive guide through emerging concepts and demonstrates how the available mutation screening technology can be implemented in diagnostic laboratories and provide better healthcare
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