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Design and Analysis of Clinical Trials with Time-to-Event Endpoints, 


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Название:  Design and Analysis of Clinical Trials with Time-to-Event Endpoints   (Проект и анализ клинических испытаний с конечными точками времени)
Издательство: Taylor&Francis
Классификация:
Медицинское оборудование и методы

ISBN: 1420066390
ISBN-13(EAN): 9781420066395
ISBN: 1-420-06639-0
ISBN-13(EAN): 978-1-420-06639-5
Обложка/Формат: Hardback
Страницы: 616
Вес: 0.978 кг.
Дата издания: 15.02.2009
Серия: Chapman & hall/crc biostatistics series
Язык: ENG
Иллюстрации: 95 black & white illustrations, 107 black & white tables
Размер: 23.11 x 16.51 x 3.81 cm
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: Provides a presentation of the design, monitoring, analysis, and interpretation of clinical trials in which time-to-event is of critical interest. This book discusses the design and monitoring of Phase II and III clinical trials with time-to-event endpoints.
Дополнительное описание:




Solutions Manual to Accompany Applied Survival Analysis: Regression Modeling of Time to Event Data

Автор: David W. Hosmer Jr.
Название: Solutions Manual to Accompany Applied Survival Analysis: Regression Modeling of Time to Event Data
ISBN: 0471249793 ISBN-13(EAN): 9780471249795
Издательство: Wiley
Цена: 2351 р.
Наличие на складе: Поставка под заказ.

Описание: Recent years have seen a major growth in the development of methods for analyzing survival time data. At the same time, there has been little in the statistical literature to guide researchers in health-related areas who study time-to-event data. Applied Survival Analysis fills this gap, providing a comprehensive, self-contained introduction to regression modeling used in the analysis of time-to-event data in epidemiological, biostatistical, and other health-related research.

Biomarkers and Surrogate Endpoints: Clinical Research and Applications,1205

Автор: G. J. Downing
Название: Biomarkers and Surrogate Endpoints: Clinical Research and Applications,1205
ISBN: 0444503161 ISBN-13(EAN): 9780444503169
Издательство: Elsevier Science
Цена: 9537 р.
Наличие на складе: Невозможна поставка.

Описание: The potential adaptation of biomarkers as substitutes for clinical endpoints, or surrogate endpoints, in clinical trials has recently taken on new importance. This volume summarizes the proceedings of the first international, multi-disciplinary conference held to discuss this important issue. A historical perspective is provided on the use of biomarkers in drug development, as diagnostic and clinical measuring tools, and in some cases their application as surrogate endpoints in diseases such as AIDS, cancer, and cardiovascular disease. Also included is a review of concepts, terminology, and examples which provide a background for those who are not familiar with the use of biomarkers in drug development and clinical trials. There is presently no other publication which gives such a unique insight into the current state of understanding of biomarkers for specific disease areas, and the emerging tools and technologies that may be used to discover and evaluate biomarkers. The book also focuses on areas of need or interest in identifying new biomarkers, and key issues for researchers in applying them in drug development and clinical trials.

The Evaluation of Surrogate Endpoints

Автор: Burzykowski
Название: The Evaluation of Surrogate Endpoints
ISBN: 0387202773 ISBN-13(EAN): 9780387202778
Издательство: Springer
Рейтинг:
Цена: 15427 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: How can one establish the adequacy of a surrogate? This book offers an account on this controversial topic. It presents major developments of the last couple of decades, together with a meta-analytic framework within which surrogates can be evaluated from several angles.

Design and Analysis of Quality of Life Studies in Clinical Trials

Автор: Fairclough
Название: Design and Analysis of Quality of Life Studies in Clinical Trials
ISBN: 1584882638 ISBN-13(EAN): 9781584882633
Издательство: Taylor&Francis
Рейтинг:
Цена: р.
Наличие на складе: Поставка под заказ.

Описание: Clinical trials often include the evaluation of Health-Related Quality of Life (HRQoL), yet many investigators remain unaware of the unique measurement and analysis issues associated with the assessment of HRQoL. Focusing on the specific features of QoL data, this book details the relevant issues and presents a range of solutions. Written from the author's extensive experience in the field, it includes SAS and S-PLUS programs, checklists, figures, and a clear presentation that combine to provide readers with the tools and skills they need to design, conduct, analyze, and report their own studies.

Design and Analysis of Clinical Trials: Concepts and Methodologies, 3rd Edition

Автор: Chow
Название: Design and Analysis of Clinical Trials: Concepts and Methodologies, 3rd Edition
ISBN: 0470887656 ISBN-13(EAN): 9780470887653
Издательство: Wiley
Рейтинг:
Цена: 13272 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Praise for the Second Edition ". . . a grand feast for biostatisticians. It stands ready to satisfy the appetite of any pharmaceutical scientist with a respectable statistical appetite." ?—Journal of Clinical Research Best Practices The Third Editio

Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition

Автор: Fairclough
Название: Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition
ISBN: 1420061178 ISBN-13(EAN): 9781420061178
Издательство: Taylor&Francis
Рейтинг:
Цена: 9090 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Using SAS, SPSS, and R, this book addresses design and analysis aspects in enough detail so that readers can apply statistical methods to their own longitudinal studies. This edition includes a new chapter on testing models that involve moderation and mediation, a new chapter on QALYs and QTWiST specific to clinical trials, and recent methodological developments for the analysis of trials with missing data. It also presents revised discussions of multiple comparisons procedures that focus on the integration of HRQoL outcomes with other study outcomes using gatekeeper strategies. Data sets, examples, applications, and SAS, R, and SPSS code are available on the book’s website.

Design and Analysis of Clinical Trials: Concepts and Methodologies, 2nd Edition

Автор: Shein-Chung Chow
Название: Design and Analysis of Clinical Trials: Concepts and Methodologies, 2nd Edition
ISBN: 0471249858 ISBN-13(EAN): 9780471249856
Издательство: Wiley
Рейтинг:
Цена: 13376 р.
Наличие на складе: Поставка под заказ.

Описание: Praise for the First Edition of Design and Analysis of Clinical Trials

Meta-Analysis of Controlled Clinical Trials

Автор: Anne Whitehead
Название: Meta-Analysis of Controlled Clinical Trials
ISBN: 0471983705 ISBN-13(EAN): 9780471983705
Издательство: Wiley
Рейтинг:
Цена: 11312 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials. The various approaches are presented within a general unified framework and meta-analysis techniques are described in detail.

Binary data analysis of randomized clinical trials with noncompliance

Автор: Lui, Kung-jong
Название: Binary data analysis of randomized clinical trials with noncompliance
ISBN: 0470660953 ISBN-13(EAN): 9780470660959
Издательство: Wiley
Рейтинг:
Цена: 8256 р.
Наличие на складе: Поставка под заказ.

Описание: It is quite common in a randomized clinical trial (RCT) to encounter patients who do not comply with their assigned treatment. Since noncompliance often occurs non-randomly, the commonly-used approaches, including both the as-treated (AT) and as-p

Design, Execution, and Management of Medical Device Clinical Trials

Автор: Salah Abdel-aleem
Название: Design, Execution, and Management of Medical Device Clinical Trials
ISBN: 0470474262 ISBN-13(EAN): 9780470474266
Издательство: Wiley
Рейтинг:
Цена: 9562 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: An essential introduction to conducting the various stages of medical device clinical trials Clinical research continues to be one of the most vital components of pharmaceutical, biostatistical, and medical studies. Design, Execution, and Management of Me

Managers` guide to the design and conduct of clinical trials

Автор: Good, Phillip I.
Название: Managers` guide to the design and conduct of clinical trials
ISBN: 0471788708 ISBN-13(EAN): 9780471788706
Издательство: Wiley
Рейтинг:
Цена: 10555 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Intended for prospective managers, this guide covers computer-assisted clinical trials. It addresses the various issues of the design and conduct of clinical trials, including study design, organization, regulatory agency liaison, data collection and analysis, as well as recruitment, software, monitoring, and reporting.

A Manager`s Guide to the Design and Conduct of Clinical Trials

Автор: Phillip I. Good
Название: A Manager`s Guide to the Design and Conduct of Clinical Trials
ISBN: 0471226157 ISBN-13(EAN): 9780471226154
Издательство: Wiley
Цена: 4964 р.
Наличие на складе: Поставка под заказ.

Описание: This engaging and non-technical guide to clinical trials covers issues study design, organization, management, analysis, recruitment, reporting, software, and monitoring. Free from the jargon-laden treatment of other books, A Manager's Guide to the Design and Conduct Clinical Trials is built upon the formula of first planning, then implementing, and finally performing essential checks.
" Offers an executive level presentation of managerial guidelines as
well as handy checklists accompanied by extracts from submitted
protocols
" Includes checklists, examples, and tips, as well as a useful appendix on available software
" Covers e-submissions and use of computers for direct data
acquisition
" Incorporates humorous yet instructive and true anecdotes to
illustrate common pitfalls


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