Описание: Contains the selected papers presented at the seventh International Symposium on Blood Substitutes (7th ISBS) held at the International Conference Center of Waseda University in Tokyo on 7-10 September 1997. This book includes clinical results of leading companies which are manufacturing hemoglobin-based or fluorocarbon-based blood substitutes.
Автор: Robert M. Winslow Название: Blood Substitutes, ISBN: 0127597603 ISBN-13(EAN): 9780127597607 Издательство: Elsevier Science Рейтинг: Цена: 24035 р. Наличие на складе: Нет в наличии.
Описание: Blood substitutes are solutions designed for use in patients who need blood transfusions, but for whom whole blood is not available, or is not safe. This book describes the rationale, approaches, clinical efficacy, and design issues for various blood substitutes in clinical trials.
Описание: Describes the use of carriers such as liposomes, micelles, dendrimers, emulsion droplets, nanoparticles, and yeast cells in the delivery of poorly water-soluble drugs, small organic molecules, macromolecules. This book is of interest to readers in the chemical and pharmaceutical industry.
Описание: Offers a comprehensive overview of the medical applications of pharmaceutical particulate carriers, discussing the various routes of administration and controlled delivery of sites of action. Intravenous liposomal therapy for retroviral infections, especially AIDS, is discussed.
Описание: This exciting area of research will benefit from the pulling together of the work from hard-core chemists and free radical aficionados along with that of signaling enthusiasts and cell biologist devotees. This was the idea behind the conception of this new book. Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles provides relevant chemistry that can be applied across signaling systems and summarizes the current state of knowledge in the area of redox signaling, including controversies when they exist and future directions. ROS and RNS have been implicated in inflammation, aging and cancer and their novel role in signal transduction may offer new clues to their participation in these processes. This volume should be of great interest to researchers involved in a large range of scientific fields from biochemistry and physiology to pharmacology.
Описание: Part I: Vascular Changes in Health and Disease. 1. Analysis of Responses to Human Synthetic Adrenomedullin and Calcitonin Gene-related Peptides in the Hindlimb Vascular Bed of the Cat; H.C. Champion, et al. 2. Effect of Short-Term Treatment with a Monoclonal Antibody to P-Selectin on Balloon Catheter-Induced: Intimal Hyperplasia, Re-Endothelialization, and Attenuation of Endothelial-Dependent Relaxation; D.L. Akers, et al. 3. Differential Regulation of G-Protein Expression by Vasoactive Peptides; M.B. Anand-Srivastava, et al. 4. Endothelin Contraction in Pig Coronary Artery: Receptor Types and Ca2+-Mobilization; A.B. Elmoselhi, A.K. Grover. 5. Activation of the Neutrophil and Loss of Plasma Glutathione During Mg-Deficiency - Modulation by Nitric Oxide Synthase Inhibition; I.T. Mak, et al. 6. Velocity of Translation of Single Actin Filaments (AF) by Myosin Heads from Antigen-Sensitized Airway Smooth Muscle; N.L. Stephens, H. Jiang. 7. Smooth Muscle Contractility and Protein Tyrosine Phosphorylation; A.K. Srivastava, J. St-Louis. 8.Coronary Artery Smooth Muscle in Culture: Migration of Heterogeneous Cell Populations from Vessel Wall; L. Saward, P. Zahradka. 9. An Overview of the Influence of ACE Inhibitors on Fetal-Placental Circulation and Perinatal Development; H.S. Buttar. Part II: Cardiac Mechanisms in Health. 10. Differential Nature of Cross-Talk Among Three G-Coupled Receptors Regulating Adenylyl Cyclase in Rat Cardiomyocytes Chronically Exposed to Receptor Agonists; P.V. Sulakhe, et al. 11. Reversal of Phosphate Induced Decreases in Force by the Benzimadazole Pyridazinone, UD-CG 212CL, in Myofilaments from Human Ventricle; L.D. Fraker, et al. 12. Expression of Fibroblast Growth Factor Receptor-1 in Rat Heart H9c2 Mycoblasts Increases Cell Proliferation; F. Sheikh, et al. 13. Identification of an HMG-Like Protein Involved in Regulation of Na+/H+ Exchanger Expression; H. Wang, et al. 14. Cytochemical nd Immunocytochemical Localization of Na,K-ATPase &agr; Subunit Isoenzymes in the Rat Heart; J. Slezák, et al. 15. Estradiol Modulates the Sodium Pump in the Heart Sarcolemma; A. Džurba, et al. 16. Thyroid Hormones Differentially Affect Sarcoplasmic Reticulum Function in Rat Atria and Ventricles; A. Kaasik, et al. 17. Dietary and Physiological Studies to Investigate the Relationship Between Calcium and Magnesium Signalling in the Mammalian Myocardium; J. Singh, et al. 18. Biological Significance of Phosphorylation and Myristoylation in the Regulation of Cardiac Muscle Proteins; R.V.S. Raju, et al. 19. Contributions of Increased Efficiency and Capacity of Protein Synthesis to Rapid Cardiac Growth; H.E. Morgan, C.J. Beinlich. 20. Cell-Cycle Dependent Anti-FGF-2 Staining of Chicken Cardiac Myocytes: Movement from Chromosomal to Cleavage Furrow- and Midbody-Associated Sites; L. Liu, et al. 21. An Endogenous Positive Inotropic Factor (EPIF) From Porcine Heart: Its Effects on Sarcoplasmic Reticular (SR) Ca2+ Metabolism; J.C. Khatter, et al. Part III: Subcellular Changes in Cardiomyopathies and Heart Failure. 22. Prostaglandins Attenuate Cardiac Contractile Dysfunction Produced by Free Radical Generation but not by Hydrogen Peroxide; M. Karmazyn, K.M. Zimmer. 23. Changes in Fatty Acid Compositions of Myocardial Lipids in Rats with Heart Failure Following Myocardial Infarction; Y. Nasa, et al. 24. Mechanisms that May be Involved in Calcium Tolerance of the Diabetic Heart; A. Ziegelhöffer, et al. 25. Increases of T-Type Ca2+ Current in Heart Cells of the Cardiomyopathic Hamster; G. Bkaily, et al. 26. Myocardial Functional Preservation During Ischemia: Influence of Beta Blocking Agents; P.M. Toleikis, C.W. Tomlinson. 2+-ATPase to Ca2+ of Myofibrils Isolated from Stunned and Not-Stunned Porcine Myocardium; K. Bezstarosti, et al. 28. Is There a Link Between Impaired Glucose Metabolism and Protein Kinase C Activity in the Diabetic Heart? S.W. Schaffer, et al. 29. A New Technique of Coronary Artery Ligation: Experimental Myocardial Infarction in Rats in Vivo With Reduced Mortality; J. Ye, et al. 30. Adriamycin Depresses in Vivo and in Vitro Phosphatidylethanolamine N-Methylation in Rat Heart Sarcolemma; N. Iliskovic, et al. 31. A Calcium Stimulated Cysteine Protease Involved in Isoproterenol Induced Cardiac Hypertrophy; G.D. Arthur, A.N. Belcastro. 32. Early Fetal Like Slow Na+ Current in Heart Cells of Cardiomyopathic Hamster; D. Jacques, et al. 33. Na+-H+ Exchange Inhibition at Reperfusion is Cardioprotective During Myocardial Ischemia-Reperfusion; 31P NMR Studies; J.C. Docherty, et al. 34. Increased Gene Expression of Plasminogen Activators and Inhibitors in Left Ventricular Hypertrophy; C.M. Bloor, et al. 35. Cardiac Hypertrophy; Old Concepts, New Perspectives; M. Gupta, M.P. Gupta. 36. Characteristics of the Myocardial PM-FABP: Effect of Diabetes Mellitus; C.E. Heyliger, et al. 37. Cardiomyopathies and Mitochondrial DNA Mutations; N. Takeda. 38. Cardiac Depression and Cellular Injury in Hemorrhagic Shock and Reinfusion: Role of Free Radicals; R. Kapoor, et al. 39. Ischemic Preconditioning is not Additive to Preservation with Hypothermia or Crystalloid Cardioplegia in the Globally Ischemic Rat Heart; J.S. Jugg, et al. Part IV: Cellular Biochemistry in Non-Cardiovascular Tissues. 40. Regulation of Ca2+ Homeostasis by Glucose Metabolism in Rat Brain; M.S. Nijjar, R. Belgrave. 41. Age and Sex-Related Differences in Nuclear Lipid Content and Nucleoside Triphosphatase Activity in the JCR:LA-cp Corpulent Rat; M.P. Czubry, et al. 42. Studies on Hepatic Injury and Antioxidant Enzyme Activities in Rat Subcellular Organelles Following In Vivo Ischemia and Reperfusion; M. Gupta, et al.
Автор: Kobayashi K., Tsuchida E., Horinouchi Hirohisa Название: Artificial Oxygen Carrier / Its Frontline ISBN: 4431220747 ISBN-13(EAN): 9784431220749 Издательство: Springer Рейтинг: Цена: 26021 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: While a reliable supply of donated blood is vital in modern medicine, it remains the case that blood transfusion comes with its own problems, such as infectious diseases, immunological adverse reactions, and difficulties with long-term storage and transportation of blood components. With a view to solving these problems, developing a suitable blood substitute has been a major goal for decades. Artificial Oxygen Carrier: Its Front Line is a compilation of reports on the concepts behind artificial oxygen carriers, as well as the new discoveries in the field that were presented during the 13th Keio International Symposium for Life Science and Medicine. This volume describes valuable topics, including artificial red blood cells, modified haemoglobin, perfluorocarbons, and haemoglobin vesicles. It explains cutting-edge developments in artificial oxygen carrier research and will be a valuable resource to all concerned with the field.
Описание: This is the first book to provide a comprehensive review of the entire area of artificial cells. The author, a pioneer of the field, invented the first artificial cells
some 50 years ago and has continued to carry out active research in this field. Since then, there have been explosive research activities around the world on artificial cells, especially in
fields related to biotechnology, nanomedicine, cell therapy, blood substitutes, drug delivery and others.
However, instead of the term "artificial cells," many authors use other
terminologies such as blood substitutes, bioencapsulation, liposomes, nanoparticles and so on. Furthermore, papers in this highly interdisciplinary area are published in numerous journals
specializing in chemistry, medicine, surgery, bioengineering and others, while books in this area are mostly multi-authored, describing very specific and narrow areas. As a result, any
meaningful literature search for a complete idea of the present status of the whole field of artificial cells is impossible.
This monograph is written to fill this gap by including all
those areas in artificial cells that are disguised under different terminologies. Each chapter begins with a detailed overview, followed by detailed examples of the author's own research
and a full description of his methods and pro
edures. Readers interested in a detailed overview of the whole area can read from cover to cover, omitting the methods section at the end of each chapter; while those entering this
area of research will find the detailed methods and procedures very useful.
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