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Animal Models of Human Related Calcium Metabolic Disorders, Ornoy, M.D.; Asher



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Автор: Ornoy, M.D.; Asher
Название:  Animal Models of Human Related Calcium Metabolic Disorders
Издательство: Informa
Классификация:
Метаболизм
Болезни и расстройства
Ортопедия и переломы

ISBN: 0849360242
ISBN-13(EAN): 9780849360244
ISBN: 0-8493-6024-2
ISBN-13(EAN): 978-0-8493-6024-4
Обложка/Формат: Hardback
Страницы: 260 pages, 47 figs.,
Вес: 0.612 кг.
Дата издания: 25/09/1995
Серия: Orthopaedics
Язык: ENG
Иллюстрации: 16 black & white tables, 12 black & white halftones
Размер: 229 x 152 mm, 1000 grams
Читательская аудитория: Professional & VocationalPostgraduate, Research &
Рейтинг:
Поставляется из: Англии
Описание: This book presents the available experimental models for common human calcium metabolic disorders. It provides valuable information for those planning animal experimental models for common and rare human bone diseases.Animal Models of Human Related Calcium Metabolic Disorders opens with a description of the major events of bone formation, growth, and remodeling in the human fetus. This is compared to bone formation in rats and mice.

Both the normal and abnormal mineralization processes in man and in laboratory animals are described.Unique to this book are the descriptions of all major skeletal dysplasias known in man and animal experimental models. Of special importance are the detailed experimental models in mice and rats where a variety of hormones and drugs transplacentally induce different types of skeletal injuries which mimic skeletal dysplasias.The effects of bone-seeking hormones on the skeleton are presented in later chapters as well as a comparison of the effects on human and animal bones, and the relation of the animal models to human growth and osteoporosis. Existing models of osteoporosis, disuse, and senescence osteoporosis are presented in depth.

The effects of newly synthesized active bisphosphonates and their potential use in the treatment of human bone diseases are also discussed.The last chapter describes several animal models of renal bone disease and includes original data on the bone structure in rats with acute and chronic renal failure, and the relevance to the situation in man. Animal Models of Human Related Calcium Metabolic Disorders will prove to be a useful reference to both students and scientists interested in all major aspects of calcium-related disorders.

Дополнительное описание:




Sphingolipids and Metabolic Disease

Автор: Cowart
Название: Sphingolipids and Metabolic Disease
ISBN: 1461406498 ISBN-13(EAN): 9781461406495
Издательство: Springer
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Цена: 17476 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others. Failure of these tissues to clear excess lipids through either metabolism or sequestration into putatively inert triacylglycerols results in perturbation of bioactive lipid metabolism in cells. In particular, aberrant generation of bioactive sphingolipids is implicated in a multitude of pathological outcomes of metabolic disease including insulin resistance, inflammation, cardiomyopathy, and others. This volume addresses not only the fundamentals of sphingolipid metabolism and analysis, but also the roles of sphingolipids in these disease processes.

The Metabolic Syndrome and Primary Care

Автор: Byrne
Название: The Metabolic Syndrome and Primary Care
ISBN: 0470512172 ISBN-13(EAN): 9780470512173
Издательство: Wiley
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Цена: 3161 р.
Наличие на складе: Поставка под заказ.

Описание: Highlights practical issues involved in managing patients with the metabolic syndrome. This book covers various aspects of the metabolic syndrome and its constituent diseases, including obesity, cardiovascular disease and diabetes. It explains the risk factors for the metabolic syndrome and how these vary among different ethnic groups.

Treatment of Metabolic Bone Disease

Автор: Hosking Md Frcp
Название: Treatment of Metabolic Bone Disease
ISBN: 1853177555 ISBN-13(EAN): 9781853177552
Издательство: Informa
Цена: 5725 р.
Наличие на складе: Нет в наличии.

Описание: A comprehensive review of pharmacologic treatments for metabolic bone disease.

A Guide to Obesity and the Metabolic Syndrome

Автор: Bray, George A.|| Bray, George A.||
Название: A Guide to Obesity and the Metabolic Syndrome
ISBN: 1439814570 ISBN-13(EAN): 9781439814574
Издательство: Taylor&Francis
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Цена: 17243 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

In the historical record there is abundant evidence that obesity was a medical and health concern as long as medicine has been practiced. The idea of diet and exercise are bulwarks in the fight against obesity in history from the time of Hippocrates to the 16th century?a span of 2,000 years. However, our scientific understanding of this problem is only a little over 200 years old. An examination of the root cause of what many consider the obesity epidemic, A Guide to Obesity and the Metabolic Syndrome traces the origins and types of obesity and its treatment.

Examining in detail the developing treatment for obesity, this book provides:

  • A history of obesity, including treatment, proposed causes, and perceptions
  • An examination of the causes and problems associated with obesity
  • A discussion of lifestyle, diet, exercise, and treatment strategies
  • A detailed look at the medications and surgeries available for obesity


The fact that we have an epidemic of obesity today that is covering the globe suggests that the strategically simple ideas of eating less and exercising more, ideas that require commitment and personal involvement by the individual, have not been very successful. As we move forward in trying to understand this problem, we need to be alert to strategies and tactics that may not require individual motivation and commitment?history has shown that they do not work well. This book supplies guidance on developing and designing novel strategic interventions against obesity and metabolic disorders.

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th Edition

Автор: Rosen
Название: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th Edition
ISBN: 1118453883 ISBN-13(EAN): 9781118453889
Издательство: Wiley
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Цена: 11495 р.
Наличие на складе: Поставка под заказ.

Описание: Now in an updated eighth edition, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism comprehensively covers key diseases of the bone and disorders of mineral metabolism.

Metabolic Regulation: A Human Perspective, 3rd Edition

Автор: Keith N. Frayn
Название: Metabolic Regulation: A Human Perspective, 3rd Edition
ISBN: 1405183594 ISBN-13(EAN): 9781405183598
Издательство: Wiley
Рейтинг:
Цена: 4492 р.
Наличие на складе: Поставка под заказ.

Описание: The important Third Edition of this successful book conveys a modern and integrated picture of metabolism and metabolic regulation. Explaining difficult concepts with unequalled clarity, author Keith Frayn provides the reader with an essential guide to th

The Metabolic Syndrome

Автор: Beck-Nielsen
Название: The Metabolic Syndrome
ISBN: 370911330X ISBN-13(EAN): 9783709113301
Издательство: Springer
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Цена: 17764 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Linked to inactive lifestyle and obesity, the metabolic cyndrome can develop into type 2 diabetes, cardiovascular disease and cancer. This book reviews lifestyle intervention and pharmacological treatment, offering a strategy for treatment in the daily clinic.

Systems Metabolic Engineering

Автор: Wittmann
Название: Systems Metabolic Engineering
ISBN: 9400745338 ISBN-13(EAN): 9789400745339
Издательство: Springer
Рейтинг:
Цена: 17476 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.

Pediatric Metabolic Syndrome

Автор: Lipshultz
Название: Pediatric Metabolic Syndrome
ISBN: 1447123654 ISBN-13(EAN): 9781447123651
Издательство: Springer
Рейтинг:
Цена: 15894 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In just under three decades, the world has witnessed an enormous rise in obesity with a parallel growth  in cardiometabolic disease risk factors characterized by insulin resistance, dyslipidemia, and hypertension, together known as the metabolic syndrome - conditions previously unheard of in children and adolescents. During this time, we have little knowledge of the global and cumulative detrimental health effects of childhood obesity. As obese children age, not only will their health be negatively affected, but infertility and pregnancy complications associated with the metabolic syndrome will affect generations to come.  The work force will undoubtedly be affected because of increased sick days and decreased work productivity. Identifying children and adolescents at the earliest stages of chronic disease onset should be the goal of clinical practice, yet there is no clear guidance for defining the risk of metabolic syndrome or appropriate risk-factor thresholds in these groups.  If children are identified early in the disease process, lifestyle and clinical interventions can be instituted when they are potentially more effective. Pediatric Metabolic Syndrome: Comprehensive Clinical Review and Related Health Issues approaches the pediatric metabolic syndrome by elucidating its effects on specific organ systems and by considering the problem through understanding the social, psychological and economic consequences of it.  The Editors have recruited an invited group of esteemed experts in the field to provide the most timely and informative approaches on how to deal with this health crisis.  Through educating our practitioners, our future researchers, our health and community organizations, our legislators and our families and children, we have the best chance at improving the health trajectory of the next generation.

Metabolic Syndrome: Underlying Mechanisms and Drug Therapies

Автор: Wang
Название: Metabolic Syndrome: Underlying Mechanisms and Drug Therapies
ISBN: 0470343427 ISBN-13(EAN): 9780470343425
Издательство: Wiley
Рейтинг:
Цена: 12645 р.
Наличие на складе: Поставка под заказ.

Описание: This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, th

Nutritional and Metabolic Bases of Cardiovascular Disease

Автор: Mancini
Название: Nutritional and Metabolic Bases of Cardiovascular Disease
ISBN: 1405182768 ISBN-13(EAN): 9781405182768
Издательство: Wiley
Рейтинг:
Цена: 13036 р.
Наличие на складе: Поставка под заказ.

Описание: Discusses the relationships between nutrition, metabolism, and cardiovascular disease. This book examines the role of obesity, hyperlipidemia diabetes, hypertension, thrombosis, and aging in atherogenesis. It describes scientific and clinical evidence of the etiopathogenesis of ischemic heart disease, peripheral and cerebrovascular disease.

Cytochromes P450: Metabolic and Toxicological Aspects

Автор: Ioannides; Costas
Название: Cytochromes P450: Metabolic and Toxicological Aspects
ISBN: 0849392241 ISBN-13(EAN): 9780849392245
Издательство: Informa
Рейтинг:
Цена: 16133 р.
Наличие на складе: Нет в наличии.

Описание: An in-depth book on the role of cytochrome P450 proteins from a toxicological perspective, Cytochromes P450: Metabolics and Toxicological Aspects examines the proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Contributions from internationally acknowledged experts include an overview, profiles of each of the cytochrome P450 families and subfamilies involved in chemical metabolism, and recent issues and developments of interest. It is a useful source for research scientists, especially those working in the pharmaceutical industry, dealing with the safety evaluation of chemicals and the study of their metabolism, and toxicological properties.


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