Animal Models of Human Related Calcium Metabolic Disorders, Ornoy, M.D.; Asher
Автор: Cowart Название: Sphingolipids and Metabolic Disease ISBN: 1461406498 ISBN-13(EAN): 9781461406495 Издательство: Springer Рейтинг: Цена: 17476 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others. Failure of these tissues to clear excess lipids through either metabolism or sequestration into putatively inert triacylglycerols results in perturbation of bioactive lipid metabolism in cells. In particular, aberrant generation of bioactive sphingolipids is implicated in a multitude of pathological outcomes of metabolic disease including insulin resistance, inflammation, cardiomyopathy, and others. This volume addresses not only the fundamentals of sphingolipid metabolism and analysis, but also the roles of sphingolipids in these disease processes.
Описание: Highlights practical issues involved in managing patients with the metabolic syndrome. This book covers various aspects of the metabolic syndrome and its constituent diseases, including obesity, cardiovascular disease and diabetes. It explains the risk factors for the metabolic syndrome and how these vary among different ethnic groups.
Автор: Hosking Md Frcp Название: Treatment of Metabolic Bone Disease ISBN: 1853177555 ISBN-13(EAN): 9781853177552 Издательство: Informa Цена: 5725 р. Наличие на складе: Нет в наличии.
Описание: A comprehensive review of pharmacologic treatments for metabolic bone disease.
Автор: Bray, George A.|| Bray, George A.|| Название: A Guide to Obesity and the Metabolic Syndrome ISBN: 1439814570 ISBN-13(EAN): 9781439814574 Издательство: Taylor&Francis Рейтинг: Цена: 17243 р. Наличие на складе: Есть у поставщика Поставка под заказ.
In the historical record there is abundant evidence that obesity was a medical and health concern as long as medicine has been practiced. The idea of diet and exercise are bulwarks in the fight against obesity in history from the time of Hippocrates to the 16th century?a span of 2,000 years. However, our scientific understanding of this problem is only a little over 200 years old. An examination of the root cause of what many consider the obesity epidemic, A Guide to Obesity and the Metabolic Syndrome traces the origins and types of obesity and its treatment.
Examining in detail the developing treatment for obesity, this book provides:
A history of obesity, including treatment, proposed causes, and perceptions
An examination of the causes and problems associated with obesity
A discussion of lifestyle, diet, exercise, and treatment strategies
A detailed look at the medications and surgeries available for obesity
The fact that we have an epidemic of obesity today that is covering the globe suggests that the strategically simple ideas of eating less and exercising more, ideas that require commitment and personal involvement by the individual, have not been very successful. As we move forward in trying to understand this problem, we need to be alert to strategies and tactics that may not require individual motivation and commitment?history has shown that they do not work well. This book supplies guidance on developing and designing novel strategic interventions against obesity and metabolic disorders.
Описание: Now in an updated eighth edition, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism comprehensively covers key diseases of the bone and disorders of mineral metabolism.
Описание: The important Third Edition of this successful book conveys a modern and integrated picture of metabolism and metabolic regulation. Explaining difficult concepts with unequalled clarity, author Keith Frayn provides the reader with an essential guide to th
Автор: Beck-Nielsen Название: The Metabolic Syndrome ISBN: 370911330X ISBN-13(EAN): 9783709113301 Издательство: Springer Рейтинг: Цена: 17764 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Linked to inactive lifestyle and obesity, the metabolic cyndrome can develop into type 2 diabetes, cardiovascular disease and cancer. This book reviews lifestyle intervention and pharmacological treatment, offering a strategy for treatment in the daily clinic.
Автор: Wittmann Название: Systems Metabolic Engineering ISBN: 9400745338 ISBN-13(EAN): 9789400745339 Издательство: Springer Рейтинг: Цена: 17476 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.
Автор: Lipshultz Название: Pediatric Metabolic Syndrome ISBN: 1447123654 ISBN-13(EAN): 9781447123651 Издательство: Springer Рейтинг: Цена: 15894 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In just under three decades, the world has witnessed an enormous rise in obesity with a parallel growth in cardiometabolic disease risk factors characterized by insulin resistance, dyslipidemia, and hypertension, together known as the metabolic syndrome - conditions previously unheard of in children and adolescents. During this time, we have little knowledge of the global and cumulative detrimental health effects of childhood obesity. As obese children age, not only will their health be negatively affected, but infertility and pregnancy complications associated with the metabolic syndrome will affect generations to come. The work force will undoubtedly be affected because of increased sick days and decreased work productivity. Identifying children and adolescents at the earliest stages of chronic disease onset should be the goal of clinical practice, yet there is no clear guidance for defining the risk of metabolic syndrome or appropriate risk-factor thresholds in these groups. If children are identified early in the disease process, lifestyle and clinical interventions can be instituted when they are potentially more effective. Pediatric Metabolic Syndrome: Comprehensive Clinical Review and Related Health Issues approaches the pediatric metabolic syndrome by elucidating its effects on specific organ systems and by considering the problem through understanding the social, psychological and economic consequences of it. The Editors have recruited an invited group of esteemed experts in the field to provide the most timely and informative approaches on how to deal with this health crisis. Through educating our practitioners, our future researchers, our health and community organizations, our legislators and our families and children, we have the best chance at improving the health trajectory of the next generation.
Описание: This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug development. The authors examine the context of underlying molecular pathways and integrated physiology, th
Описание: Discusses the relationships between nutrition, metabolism, and cardiovascular disease. This book examines the role of obesity, hyperlipidemia diabetes, hypertension, thrombosis, and aging in atherogenesis. It describes scientific and clinical evidence of the etiopathogenesis of ischemic heart disease, peripheral and cerebrovascular disease.
Описание: An in-depth book on the role of cytochrome P450 proteins from a toxicological perspective, Cytochromes P450: Metabolics and Toxicological Aspects examines the proteins and their role in toxicity/carcinogenicity and the metabolism of foreign chemicals. Contributions from internationally acknowledged experts include an overview, profiles of each of the cytochrome P450 families and subfamilies involved in chemical metabolism, and recent issues and developments of interest. It is a useful source for research scientists, especially those working in the pharmaceutical industry, dealing with the safety evaluation of chemicals and the study of their metabolism, and toxicological properties.
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