Автор: Ruddon Название: Cancer Biology 4/e C ISBN: 0195175433 ISBN-13(EAN): 9780195175431 Издательство: Oxford University Press Цена: 6336.00 р. Наличие на складе: Невозможна поставка. Описание: A thorough yet concise account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into
malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It also defines the fundamental pathophysiological
changes that occur in tumor tissue and in the host animal or patient. The approach throughout the book is to discuss the historical development of a field, citing the key experimental
advances to the present day, and to evaluate the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell
behavior.
For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well illustrated
with schematic diagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography. In this revision, Dr.
Ruddon has
organized his text to provide more integrated discussion of the many topics covered in the third edition,. . At the same time, he has included much new material on molecular genetics
and genetic diagnosis (e.g., DNA microarrays to mark tumors), RNA interference, stem cells, cell cycle regulation, angiogenesis, etc.
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