Cancer Stem Cells, Yu

Автор: Mathews
Название: DNA Repair of Cancer Stem Cells
ISBN: 9400745893 ISBN-13(EAN): 9789400745896
Издательство: Springer
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Цена: 22203.00 р.
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Описание: The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.

Автор: Sadhan Majumder (Ed.)
Название: Stem Cells and Cancer
ISBN: 0387896104 ISBN-13(EAN): 9780387896106
Издательство: Springer
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Цена: 26122.00 р.
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Описание: Cancer is a primary cause of human mortality worldwide. This book intends to impart information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.

Автор: Hayat
Название: Stem Cells and Cancer Stem Cells, Volume 1
ISBN: 9400717083 ISBN-13(EAN): 9789400717084
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Difference between tissue specific stem cells and embryonic stem cells is explained. The advantages of the latter are included. The application of human pluripotent stem cells, mesenchymal stem cells, and hematopoietic stem cells in cancer therapy and tissue/organ regeneration is detailed. Role of neural cancer stem cells in brain tumors, including their role in brain tumor therapy and the role of CD133 stem cell antigen in glioma patients, is emphasized. Therapeutic role of bone marrow-derived stem cells in myocardial infarction and the role of mesenchymal stem cells in orthopedics are explained. Transplantation of umbilical cord hematopoietic stem cells and allogeneic hematopoietic stem cell transplantation followed by graft-versus-host disease are presented. Role of cancer stem cells specifically in glioblastoma and medulloblastoma is included. It is also emphasized that CD133 is an appropriate stem cell marker for gliomas. Targeting of cancer cells is also explained.

Автор: Otmar D. Wiestler; Bernhard Haendler; D. Mumberg
Название: Cancer Stem Cells
ISBN: 3540708529 ISBN-13(EAN): 9783540708520
Издательство: Springer
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Цена: 30039.00 р.
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Описание: Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. They have very different properties from the bulk of the tumor as they divide much more slowly and have very efficient drug resistance mechanisms. This book looks at various developments in the field of cancer stem cells.

Автор: Otmar D. Wiestler; Bernhard Haendler; D. Mumberg
Название: Cancer Stem Cells
ISBN: 3642420869 ISBN-13(EAN): 9783642420863
Издательство: Springer
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Цена: 26120.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. Current treatments might largely spare cancer stem cells. This book looks at recent developments in the field of cancer stem cells and the possible impact for the identification of novel treatment paradigms for cancer.