Автор: Thurston
Название: Chemistry and Pharmacology of Anticancer Drugs, Second Edition
ISBN: 1439853266 ISBN-13(EAN): 9781439853269
Издательство: Taylor&Francis
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Цена: 11688 р.
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Описание: Bringing together a broad spectrum of information relating to the chemistry and pharmacology of anticancer drugs and therapies, this book covers the complete range of anticancer drug families and the chemical structures of all anticancer agents in clinical use, many at the research or clinical evaluation stage. The second edition features a new chapter on the quest for selectivity, which has become increasingly important in developing targeted drugs, that includes a table of all therapeutic classes along with their benefits and challenges. The text provides up-to-date information on biomarkers, pharmacogenetics and pharmacogenomics as well as agents used in the palliative care of cancer patients.

Автор: Teicher
Название: Anticancer Drug Development Guide. 2ed.2004
ISBN: 1588292282 ISBN-13(EAN): 9781588292285
Издательство: Springer
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Цена: 20543 р.
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Описание: This thoroughly updated and expanded second edition of Beverly Teicher's widely used classic survey provides a step-by-step guide to anticancer drug development from initial design through FDA approval. The authors have included new material on the use of high throughput screening in industry, on specialized in vitro/in vivo procedures employed by the National Cancer Institute (NCI) in preclinical drug evaluations, and on nonclinical testing to support both human clinical trials, as well as trials of biologic oncology products. The chapters on phase I, II, and III clinical trials and on novel phase II clinical trial designs for targeted therapies have been significantly updated, along with those on cancer drug development in Europe, working with the NCI, and the FDA's role in cancer drug development and setting requirements for approval.

Автор: Garrett-Mayer
Название: Principles of Anticancer Drug Development
ISBN: 1441973575 ISBN-13(EAN): 9781441973573
Издательство: Springer
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Цена: 15420 р.
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Описание: A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs.

Автор: Cho
Название: Evidence-based Anticancer Materia Medica
ISBN: 9400705255 ISBN-13(EAN): 9789400705258
Издательство: Springer
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Цена: 16962 р.
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Описание: Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers.Recently there have been encouraging results from both laboratory experiments and clinical trials demonstrating the anticancer effects of herbal medicine. There is considerable interest among oncologists and cancer researchers to find anticancer agents in herbal medicine. This volume is a specialised book presenting the up-to-date scientific evidence for anticancer herbal medicine. This unique book provides an overview of the anticancer herbal medicines and remedies, as well as a detailed evidence-based evaluation of 18 common anticancer herbal medicines covering their biological and pharmacological properties, efficacies, herb-drug interactions, adverse effects, pre-clinical studies, and clinical applications.Gathering international opinion leaders’ views, this volume will contribute great to the cancer, academic, and clinical community by providing evidence-based information on the anticancer efficacy of herbal medicine.ReadershipOncologists, cancer researchers, pharmacologists, pharmaceutical specialists, Chinese medicine practitioners, medical educators, postgraduates and advanced undergraduates in biomedical disciplines, cancer caregivers, cancer patients.

Автор: Robert M. Snapka
Название: The SV40 Replicon Model for Analysis of Anticancer Drugs,
ISBN: 0126536309 ISBN-13(EAN): 9780126536300
Издательство: Elsevier Science
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Цена: 8910 р.
Наличие на складе: Нет в наличии.

Описание: Provides a review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. This book focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. It covers the high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication.

Автор: Gordon M. Cragg
Название: Anticancer Agents from Natural Products, Second Edition
ISBN: 1439813825 ISBN-13(EAN): 9781439813829
Издательство: Taylor&Francis
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Цена: 11314 р.
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Описание: "This book covers clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. The second edition includes drugs that are currently in development. In addition, the text emphasizes the applications of synthetic and medicinal chemistry to the preparation of analogs with enhanced activities. Contributors also address the potential of novel drug discovery through the use of genome mining as well as the status of advanced development candidates. For each compound of class of compounds, the text provides information on the history, structure, mechanism of action, development, synthesis, medicinal chemistry, and clinical applications"--

Автор: Federico Innocenti
Название: Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response
ISBN: 1617376949 ISBN-13(EAN): 9781617376948
Издательство: Springer
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Цена: 16961 р.
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Описание: This book addresses the role of genomic information in cancer therapy and in drug development. It provides the most comprehensive body of knowledge on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients.

Автор: Bruce C. Baguley
Название: Anticancer Drug Development,
ISBN: 0120726513 ISBN-13(EAN): 9780120726516
Издательство: Elsevier Science
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Цена: 11798 р.
Наличие на складе: Нет в наличии.

Описание: Presents a spectrum of ideas on the development of anticancer drugs. Containing reviews of multidisciplinary fields of research, this book offers ideas on molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. It includes descriptions of sources for drugs and methods for testing.

Автор: Figg William D., McLeod Howard L.
Название: Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
ISBN: 1588291774 ISBN-13(EAN): 9781588291776
Издательство: Springer
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Цена: 15671 р.
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Описание: Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.

Автор: Buolamwini John K., Adjei Alex A.
Название: Novel Anticancer Drug Protocols
ISBN: 0896039633 ISBN-13(EAN): 9780896039636
Издательство: Springer
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Цена: 15419 р.
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Описание: This book not only surveys the whole arena of novel anticancer drug targets, but also presents a wide-ranging selection of cutting-edge techniques currently being applied throughout novel antitumor drug discovery and development. The methods are applied to experiments involving such topics as immunotherapy, angiogenesis, cancer metastasis, the cell cycle, signal transduction inhibitors, apoptosis, antibodies, antisense molecules, microarray gene expression, flow cytometry, and PET imaging for cancer target validation. There are also proven methods for the preclinical identification of drug targets and for target validation during the clinical trials of novel agents.

Автор: L. Harivardhan Reddy; Patrick Couvreur
Название: Macromolecular Anticancer Therapeutics
ISBN: 1461424925 ISBN-13(EAN): 9781461424925
Издательство: Springer
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Цена: 21588 р.
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Описание: This book details the macromolecular therapeutics for cancer therapy. It also covers the classification of these anticancer drugs based on therapeutic targets and elaborates on different classes of anticancer therapeutics.

Автор: L. Harivardhan Reddy; Patrick Couvreur
Название: Macromolecular Anticancer Therapeutics
ISBN: 1441905065 ISBN-13(EAN): 9781441905062
Издательство: Springer
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Цена: 21588 р.
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Описание: Cancer treatment using Macromolecular therapeutics has considerably improved the survival benefit for the patients. This book assembles various types and aspects of macromolecular anticancer therapeutics for cancer therapy and conveys the importance of this interdisciplinary field.