Описание: Proceedings of the Light-Activated Tissue Regeneration and Therapy II Conference covers issues such as the latest advances in the field and measurements including the determination of the mechanisms of light-activated tissue regeneration and therapy. Light sources, narrow and broadband, as well as the metrology and medical outcomes they produce, will be discussed.This book discusses the following topics: Laser therapy; Mechanism; Photodynamic therapy; Cardiovascular; Pain; Neuroscience/Progenitor and Stem cells; Wound healing; Unusual Sources; Electrical Fields, Optical Fields and Other fields; Dentistry; Diabetes.This book is the first to present the mechanism which explains why light is an effective treatment for so many illnesses and diseases. Proceedings of the Light-Activated Tissue Regeneration and Therapy II Conference not only explains this mechanism, but also describes uses for the mechanism, as well as what new work is planned and what changes will be seen in FDA regulations.
Автор: Marc S. Penn Название: Stem Cells and Myocardial Regeneration ISBN: 1617377058 ISBN-13(EAN): 9781617377051 Издательство: Springer Рейтинг: Цена: 21412 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF).
Автор: Penn Название: Stem Cells & Myocardial Regeneration. 2007 ISBN: 1588296644 ISBN-13(EAN): 9781588296641 Издательство: Springer Рейтинг: Цена: 21412 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presents the state of knowledge of cell based myocardial regeneration including focuses on findings in both the laboratory and the clinic trials. This book focuses on the magnitude of the problem of congestive heart failure diagnosed each year; followed by sections on the science behind cell based myocardial regeneration.
Автор: Keiichi Fukuda (Editor) Название: Cardiac Regeneration using Stem Cells ISBN: 1466578394 ISBN-13(EAN): 9781466578395 Издательство: Taylor&Francis Рейтинг: Цена: 13063 р. Наличие на складе: Невозможна поставка.
Описание: To achieve cardiac regeneration using pluripotent stem (iPS) cells, researchers must understand iPS cell generation methods, cardiomyocyte differentiation protocols, cardiomyocyte characterization methods, and tissue engineering. This book presents the current status and future possibilities in cardiac regeneration using iPS cells. Written by top researchers who present new data in these fields, this book reviews cardiac cell therapy for ischemic heart disease and explores in vitro generation of efficacious platelets from iPS cells. It also discusses modeling arrhythmogenic heart disease with patient-specific induced pluripotent stem cells.
Автор: Engel, Felix B. Название: Heart Regeneration: Stem Cells & Beyond ISBN: 9814299804 ISBN-13(EAN): 9789814299800 Издательство: World Scientific Publishing Рейтинг: Цена: 13964 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Injured mammalian hearts do not regenerate but scar. This is a major medical problem, as ischemic heart disease is among the leading causes of morbidity and mortality worldwide. Essential clues for human heart repair are uncovered when zebrafish and newt are found to regenerate cardiac muscle after injury.This book presents the major advances of the last decade in the field of cardiac regeneration. These recent advances include: demonstration that zebrafish, a genetically tractable system, can regenerate heart; the identification of several new stem cell populations in the heart; demonstration that stem cells can be used to improve heart function; and demonstration that induction of cardiomyocyte proliferation is a realistic future option to repair injured hearts. This book also provides detailed reviews of the research on model organisms capable of heart regeneration as well as innovative translational research to achieve regeneration in mammals, that comprises work on blood born stem cells, endogenous cardiac stem cells, paracrine factors, reawakening of cardiomyocyte proliferation, and bioengineering. More importantly, the book, in the concluding chapter, dovetails the studies with a comprehensive overview of clinical trials.
The second volume in the Stem Cells series concentrates on the mechanisms of stem cell regeneration in the adult organism with a view towards understanding how lost tissue can be replaced during adulthood and aging. The second focus of this volume is on stem cell identification and manipulation, including applications in basic research, medicine, and industry. The book closes with an outlook on generalized approaches that can be used to solve legislative and ethical challenges.
Описание: This book is the definitive reference on two of the most exciting areas of cardiovascular research - myocardial regeneration and stem cell therapy - for the treatment of disease. Edited by pioneers in the area, with contributions from every major inve
Описание: The fact that the cardiovascular system transports oxygen and nutrients to all parts of the body makes any threat to its well-being a serious hazard to organs, tissues, and cells. This fundamental truth underlines the importance of research into cardiovascular regeneration and, therefore, of this collection outlining the latest developments in the field. With input from many of the leading researchers and practitioners, this book describes techniques for therapeutic angiogenesis and vasculogenesis for the treatment of ischemic diseases and examines the current approaches to angiogenic cytokines, cardiovascular stem cells, and tissue-engineering tools. The latest clinical results using bone marrow-derived mononuclear cell therapy for intractable circulatory disorders are also covered. This body of work will be a valuable resource for professionals in the fields of cardiovascular surgery, regenerative medicine, and tissue engineering.
Recent advances in technology have led to the unprecedented accuracy in measurements of endogenous electric fields around sites of tissue disruption. State-of-the-art molecular approaches demonstrate the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. New information indicates that electric fields play a role in initiating and coordinating complex regenerative responses in development and wound repair and that they may also have a part in cancer progression and metastasis.
Compiling current research in this rapidly expanding field, Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer highlights relevant, cutting-edge topics poised to drive the next generation of medical breakthroughs. Chapters consider methods for detecting endogenous electric field gradients and studying applied electric fields in the lab. The book addresses bioelectricity's roles in guiding cell behavior during morphogenesis and orchestrating higher order patterning. It also covers the response of stem cells to applied electric fields, which reveals bioelectricity as an exciting new player in tissue engineering and regenerative medicine.
This book provides an in-depth exploration of how electric signals control corneal wound repair and skin re-epithelialization, angiogenesis, and inflammation. It also delves into the bioelectric responses of cells derived from the musculoskeletal system, bioelectrical guidance of neurons, and the beneficial application of voltage gradients to promote regeneration in the spinal cord. It concludes with a discussion of bioelectricity and cancer progression and the potential for novel cancer biomarkers, new methods for early detection, and bioelectricity-based therapies to target both the tumor and metastatic cancer cells.
This multidisciplinary compilation will benefit biologists, biochemists, biomedical scientists, engineers, dermatologists, and clinicians, or anyone else interested in development, regeneration, cancer, and tissue engineering. It can also serve as an ideal textbook for students in biology, medicine, medical physiology, biophysics, and biomedical engineering.
Heart disease is the leading cause of death in the UK and the United States. For those people who survive heart disease, few victims recover completely. Cell therapies, tissue engineering and biomaterials technologies have advanced and now offer the potential to reverse the damage caused by heart disease.
Volume 1 of this important book provides readers with comprehensive information on biomaterials and tissue engineering as strategies for the repair and regeneration of the heart. The book begins with an introduction to the field, and following chapters look at biomaterials for regeneration and repair of the heart. Further chapters discuss tissue engineering strategies for the regeneration and repair of the heart whilst the final chapters review vascular modelling and regeneration.
Volume 2 reviews the use of biomaterials, alone or combined with cell therapy, to provide tissue engineered constructs to repair the injured heart and prevent or reverse heart failure.
Описание: The topic of heart failure although extensively researched and reported, has several gray areas. This is especially seen in determining strategies for combating advanced heart failure. The global burden of ischemic heart disease is increasing at an alarming rate to almost pandemic proportions. Even in the presence of state-of the art technology for prompt and successful coronary reperfusion, the population progressing to ischemic cardiomyopathy is substantial. The treatment strategies for ischemic cardiomyopathy do not always ensure optimal clinical results, the reasons for which are varied. The proper patient selection is vital as is the tailoring of suitable therapy. The approach is thus multi-pronged, of which surgical ventricular restoration (SVR) has a definite role. Despite various randomized studies like the STICH-hypothesis 2, where there was a huge selection bias, with patients subjected to an erroneous technique of SVR, with inadequate ventricular remodelling assessment. The present need is to understand the unique anatomy of the left ventricle, its function and perturbations with the onset of heart failure, in order to plan therapeutic strategies to restore near normal anatomy and function. A study of the hemodynamics in ischemic cardiomyopathy is essential, as it differs in certain aspects from other causes of heart failure like idiopathic dilated cardiomyopathy and valvular heart diseases. Since information on these aspects are scattered in various scholarly articles, a concise source in the form of a book would be appropriate and useful for both cardiologists and cardiac surgeons. This project represents a concise review of normal and abnormal cardiac anatomy and physiology, the evolution of SVR to EVLPP with validation of near normal ventricular restoration, plus act as a reference guide for cardiac surgeons with interest in SVR.
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