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Histopathology of Preclinical Toxicity Studies,, Peter Greaves

Автор: Peter Greaves
Название:  Histopathology of Preclinical Toxicity Studies,   (Петер Гревс: Гистопатология. Доклинические исследования отравлений)
Издательство: Elsevier Science
Классификация:
Медицинское оборудование и методы
Фармакология

ISBN: 0444538569
ISBN-13(EAN): 9780444538567
ISBN: 0-444-53856-9
ISBN-13(EAN): 978-0-444-53856-7
Обложка/Формат: Hardback
Страницы: 892
Вес: 2.532 кг.
Дата издания: 23.11.2011
Серия: Life Sciences
Язык: ENG
Издание: 4 rev ed
Иллюстрации: Approx. 200 illustrations (50 in full color)
Размер: 23.88 x 19.81 x 4.32 cm
Читательская аудитория: Professional & vocational
Подзаголовок: Interpretation and relevance in drug safety evaluation
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: Describes the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. This reference is suitable for those involved in drug safety evaluation, including pathologists, toxicologists, and pharmacologists.
Дополнительное описание:


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Склад Англия: 1шт.  
При оформлении заказа до: 15 июн 2018
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  Старое издание
Histopathology Of Preclinical Toxicity Studies, Interpretation An

Автор: Greaves
Название: Histopathology Of Preclinical Toxicity Studies, Interpretation An
ISBN: 0444505148 ISBN-13(EAN): 9780444505149
Издательство: Elsevier Science
Цена: 25344 р.
Наличие на складе: Невозможна поставка.

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Histopathology of preclinical toxicity studies

Автор: Greaves, Peter
Название: Histopathology of preclinical toxicity studies
ISBN: 0444527710 ISBN-13(EAN): 9780444527714
Издательство: Elsevier Science
Цена: 11436 р.
Наличие на складе: Невозможна поставка.
Описание: Covers various aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. This work relates to the preclinical safety assessment of new medicines. It also covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies.

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Preclinical safety evaluation of biopharmaceuticals

Название: Preclinical safety evaluation of biopharmaceuticals
ISBN: 0470108843 ISBN-13(EAN): 9780470108840
Издательство: Wiley
Рейтинг:
Цена: 15241 р.
Наличие на складе: Поставка под заказ.

Описание: Includes an overview of biopharmaceuticals with information on regulation and methods of production. This book discusses the principles of ICH S6 and their implementation in the US, Europe, and Japan. It covers practices in preclinical development and compares safety assessments for small molecules with those for biopharmaceuticals.

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Evaluation of drug candidates for preclinical development

Название: Evaluation of drug candidates for preclinical development
ISBN: 0470044918 ISBN-13(EAN): 9780470044919
Издательство: Wiley
Рейтинг:
Цена: 9537 р.
Наличие на складе: Поставка под заказ.

Описание: Explaining the assessment of potential drug compounds, this title includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. It is suitable for scientists, medicinal chemists, and others working in drug discovery.

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Regenerative Medicine II / Clinical and Preclinical Applications

Автор: Yannas Ioannis V.
Название: Regenerative Medicine II / Clinical and Preclinical Applications
ISBN: 3540228683 ISBN-13(EAN): 9783540228684
Издательство: Springer
Рейтинг:
Цена: 25432 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Organ regeneration, once unknown in adult mammals, is at the threshold of maturity as a clinical method for restoration of organ function in humans. Several laboratories around the world are engaged in the development of new tools such as stem cells and biologically active scaffolds. Others are taking fresh looks at well-known clinical problems of replacement of a large variety of organs: Bone, skin, the spinal cord, peripheral nerves, articular cartilage, the conjunctiva, heart valves and urologic organs. Still other investigators are working out the mechanistic pathways of regeneration and the theoretical implications of growing back organs in an adult. The time has come to present a collection of these efforts from leading practitioners in the field of organ regeneration.

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From Morphological Imaging to Molecular Targeting / Implications to Preclinical Development

Автор: Schwaiger M., Dinkelborg L., Schweinfurth H.
Название: From Morphological Imaging to Molecular Targeting / Implications to Preclinical Development
ISBN: 3540201378 ISBN-13(EAN): 9783540201373
Издательство: Springer
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Цена: 11439 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The current progress in molecular medicine allows the identification of a plethora of new and often human-specific drug targets. An early in vivo validation of specific ligands binding to these targets in humans is needed to assess their potential for targeted imaging and radiotherapy.

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Computer Techniques in Preclinical and Clinical Drug Development

Автор: Jackson
Название: Computer Techniques in Preclinical and Clinical Drug Development
ISBN: 0849376823 ISBN-13(EAN): 9780849376825
Издательство: Taylor&Francis
Рейтинг:
Цена: 11339 р.
Наличие на складе: Поставка под заказ.

Описание: It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to a number of factors that should be, at least partially, predictable from preclinical testing. Computer Techniques in Preclinical and Clinical Drug Development asks the question, "How can we use computational methods to improve the success rate in drug development?" It shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

Short TOC

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Histopathology Specimens

Автор: Allen
Название: Histopathology Specimens
ISBN: 1852335971 ISBN-13(EAN): 9781852335977
Издательство: Springer
Рейтинг:
Цена: 8796 р.
Наличие на складе: Поставка под заказ.

Описание: Covering anatomical, clinical, pathological and laboratory aspects of surgical histopathology specimens, this book relates specimen dissection and its clinical context to relevant histopathology reports, and therefore a more comprehensive patient prognosis and management is possible.Histopathology Specimens - Clinical, Pathological and Laboratory Aspects explains pathological and clinical terminology, including a glossary of clinical request form abbreviations. It offers a standardised step-wise approach to specimen handling illustrated by simple line diagrams and highlights essentials of the histopathology report, relating them to appropriate specimen dissection. This book will act as a reference tool for the medical trainee in histopathology and the biomedical scientist, and as a useful aide memoire for the histopathology consultant.

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Histopathology Reporting

Автор: Allen
Название: Histopathology Reporting
ISBN: 1852339608 ISBN-13(EAN): 9781852339609
Издательство: Springer
Рейтинг:
Цена: 10116 р.
Наличие на складе: Поставка под заказ.

Описание: Offers a framework for standardised histopathology reports in surgical cancer. This book details the gross description, histological classification, tumor differentiation, extent of local tumor spread, involvement of lymphovascular channels, lymph nodes and excision margins of the common carcinomas and summarises non-carcinomatous malignancies.

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Anticancer Drug Toxicity: Prevention, Management, and Clinical Pharmacokinetics

Автор: Lipp
Название: Anticancer Drug Toxicity: Prevention, Management, and Clinical Pharmacokinetics
ISBN: 0824719301 ISBN-13(EAN): 9780824719302
Издательство: Informa
Рейтинг:
Цена: 11641 р.
Наличие на складе: Нет в наличии.

Описание: Containing the latest findings on the toxicity of a wide range of chemotherapeutic agents, this up-to-the-minute reference offers expert analyses on the pharmacokinetic-pharmacodynamic and pharmacokinetic-toxicodynamic relationships of anticancer compounds.
Anticancer Drug Toxicity

  • explores therapeutic drug monitoring (TDM) as a method of maximizing the efficacy, and minimizing the dangers, of chemotherapy
  • presents a vast amount of clinical pharmacokinetic data on cytostatic drugs
  • offers a comprehensive classification of toxicity patterns associated with the use of cytotoxic drugs
  • analyzes the pharmacokinetics of alkylating agents, platinum compounds, anthracyclines, antimetabolites, semisynthetic podophyllotoxin- and camptothecin derivatives, mitotic inhibitors, and other cytotoxic agents
  • highlights the pharmacogenetics of 6-mercaptopurine and its clinical significance
  • explicates toxicity in relation to the lungs, kidneys, heart, and gonads
  • examines disorders caused by asparaginase preparations
  • reviews types of secondary malignancy such as leukemias, ovarian cancer, testicular cancer, breast cancer, secondary solid neoplasias, and Hodgkin's disease
  • clarifies the understanding of toxicity as a crucial element in supportive management of cancer therapy
  • and more!
    An enormously practical guide for everyday clinical practice, as well as a source of inspiration for further research in the field, Anticancer Drug Toxicity is an invaluable reference for clinical and medical oncologists; hospital, industrial, and clinical pharmacologists and pharmacists; toxicologists; pharmaceutical chemists; radiologists; and graduate and medical school students in these disciplines.
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    Recombinant FSH (Puregon): Preclinical And Clinical Experiences (Studies In Profertility)

    Автор: Coelingh
    Название: Recombinant FSH (Puregon): Preclinical And Clinical Experiences (Studies In Profertility)
    ISBN: 1850707464 ISBN-13(EAN): 9781850707462
    Издательство: Informa
    Рейтинг:
    Цена: 5588 р.
    Наличие на складе: Нет в наличии.

    Описание: This is a collection of papers on the pre-clinical and clinical aspects of recombinant human follicle-stimulating hormone (recFSH), Puregon. The 13 articles cover FSH by specialists in obstetrics and gynaecology, reproductive medicine, reproductive endocrinology and infertility, and physiology.

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    Preclinical Development Handbook: Toxicology

    Автор: Shayne Cox Gad
    Название: Preclinical Development Handbook: Toxicology
    ISBN: 0470248467 ISBN-13(EAN): 9780470248461
    Издательство: Wiley
    Рейтинг:
    Цена: 17578 р.
    Наличие на складе: Поставка под заказ.

    Описание: This book provides drug safety and toxicology scientists with practical guidance for testing and determining the effectiveness and safety of a new drug candidate. It authoritatively covers the important topics within toxicity testing, pharmacogenomics, and regulations for the preclinical safety testing of drug candidates.

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    Preclinical Development Handbook: ADME and Biopharmaceutical Properties

    Автор: Shayne Cox Gad
    Название: Preclinical Development Handbook: ADME and Biopharmaceutical Properties
    ISBN: 0470248475 ISBN-13(EAN): 9780470248478
    Издательство: Wiley
    Рейтинг:
    Цена: 17578 р.
    Наличие на складе: Поставка под заказ.

    Описание: Guides you through preclinical drug development. This book serves as a reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. It also sets forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage.

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    Preclinical Development Handbook: 2-Volume Set

    Автор: Shayne Cox Gad
    Название: Preclinical Development Handbook: 2-Volume Set
    ISBN: 0471213837 ISBN-13(EAN): 9780471213833
    Издательство: Wiley
    Рейтинг:
    Цена: 26461 р.
    Наличие на складе: Поставка под заказ.

    Описание: Provides an overview of the preclinical process along with a compendium of methods and techniques that need to be considered when developing a new drug. This book includes problems that are encountered, solutions to these problems, and limitations of various methods and techniques used in determining the safety and efficacy of a drug.

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