Описание: A naval officer and man of science, Basil Hall (1788–1844) commanded the brig HMS Lyra as part of Lord Amherst's 1816 embassy to the Qing court in China. While Amherst was engaged on his ultimately abortive venture, the mission's ships visited the west coast of Korea, and then travelled to the island of Okinawa (then known as the Great Loo-Choo Island), where they stayed for several weeks. Little was known about these regions in Britain, and this illustrated account of the journey offered many insights. As well as providing nautical data, such as surveys, soundings and meteorological observations, Hall also comments on geography and culture. A substantial vocabulary and primer on the Okinawan language, compiled by fellow naval officer H. J. Clifford, is included in the appendix. Hall's narratives of his later travels to both North and South America are also reissued in the Cambridge Library Collection.
Описание: Now in its seventh edition, Burger's Medicinal Chemistry, Drug Discovery and Development provides an established, recognized, authoritative and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for
Описание: This book reviews diversity-oriented synthesis (DOS), a leading and dynamic area in organic chemistry and drug discovery. It first covers key chemical methods for the generation of small molecules according to DOS principles as well as important classes of molecules generated through DOS approaches.
Описание: Reflecting state-of-the-art developments, Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery reviews basic principles of micromachining as well as fluid flow and control, placing emphasis on analytical applications of microfluidic technology. This book covers micromachining methods, microfluidic operations, chemical separation, detection technology, and various chemical and biochemical analyses. The text is accessible for readers new to the field but also features various references for experienced researchers. It also adapts principles of operations on the chip, resulting in the miniaturization advantage and
Описание: Biostatistics, Second Edition, is a user-friendly guide on biostatistics, which focuses on the proper use and interpretation of statistical methods. This textbook does not require extensive background in mathematics, making it user-friendly for all students in the public health sciences field. Instead of highlighting derivations of formulas, the authors provide rationales for the formulas, allowing students to grasp a better understanding of the link between biology and statistics. The material on life tables and survival analysis allows students to better understand the recent literature in the health field, particularly in the study of chronic disease treatment. This updated edition contains over 40% new material with modern real-life examples, exercises, and references, including new chapters on Logistic Regression, Analysis of Survey Data, and Study Designs. The book is recommended for students in the health sciences, public health professionals, and practitioners.
Описание: Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in the successful development of marketable therapeutics. . The text introduces the fundamental principles of drug discovery and development, also discussing important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles in pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. It is designed to enable new scientists to rapidly understand the key fundamentals of drug discovery, including pharmacokinetics, toxicology, and intellectual property."
Описание: First defined in 1985, the field of bioorganometallic chemistry studies the role of metal ions or complexes in natural biological processes a well as the practicability of these results for the development of novel drugs, biosensors, radiopharmaceuticals,
Автор: Fischer Название: Analogue-based Drug Discovery III ISBN: 3527330739 ISBN-13(EAN): 9783527330737 Издательство: Wiley Рейтинг: Цена: 14108 р. Наличие на складе: Поставка под заказ.
Описание: Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries.
Автор: Li Название: The Drug Discovery Experience: Practices, Processes, and Perspectives ISBN: 0470942355 ISBN-13(EAN): 9780470942352 Издательство: Wiley Рейтинг: Цена: 7681 р. 10973.00-30% Наличие на складе: Есть (1 шт.) Описание: Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, t
Автор: Li Название: Heterocyclic Chemistry in Drug Discovery ISBN: 1118148908 ISBN-13(EAN): 9781118148907 Издательство: Wiley Рейтинг: Цена: 13272 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go han
Описание: Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, this book overviews plant biodiversity as a source of new drugs and drug discovery strategies.
Описание: Proteomic and Metabolomic Approaches to Biomarker Discovery demonstrates how to leverage biomarkers to improve accuracy and reduce errors in research. Disease biomarker discovery is one of the most vibrant and important areas of research today, as the identification of reliable biomarkers has an enormous impact on disease diagnosis, selection of treatment regimens, and therapeutic monitoring. Various techniques are used in the biomarker discovery process, including techniques used in proteomics, the study of the proteins that make up an organism, and metabolomics, the study of chemical fingerprints created from cellular processes. . Proteomic and Metabolomic Approaches to Biomarker Discovery is the only publication that covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods, and presents a standard operating procedure for sample selection, preparation, and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. A vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals, and graduate students, Proteomic and Metabolomic Approaches to Biomarker Discovery provides the information needed to reduce clinical error in the execution of research.
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