Systems Biology in Cancer Research and Drug Discovery, Azmi
Автор: Weinberg Robert A Название: Biology of Cancer 2 ed. ISBN: 0815345283 ISBN-13(EAN): 9780815345282 Издательство: Wiley Рейтинг: Цена: 9625 р. Наличие на складе: Есть (1 шт.) Описание: Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology. The new Second Edition has been comprehensively revised and updated to include major advances in cancer biology over the past six years. Updates include current information on: The tumor microenvironment Metastatic dissemination Tumor immunology Cancer stem cells The epithelial-mesenchymal transition Multi-step tumorigenesis Invasion and metastasis Mutation of cancer cell genomes Greatly expanded treatment of traditional therapy Epigenetic contributions MicroRNA involvement The Warburg effect Besides its value as a textbook, The Biology of Cancer is a useful reference for individuals working in biomedical laboratories and for clinical professionals. Every copy of the book comes with an updated "Pathways in Human Cancer" poster and a DVD-ROM containing the book’s art program, a greatly expanded selection of movies, audio file mini-lectures, Supplementary Sidebars, and a Media Guide.
Автор: Pelengaris Название: The Molecular Biology of Cancer, 2nd Edition ISBN: 1118008812 ISBN-13(EAN): 9781118008812 Издательство: Wiley Рейтинг: Цена: 11619 р. Наличие на складе: Есть (1 шт.) Описание: Newly revised and updated for its second edition, this comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and
Автор: Wan Название: Systems Biology of Influenza Research ISBN: 1441976523 ISBN-13(EAN): 9781441976529 Издательство: Springer Рейтинг: Цена: 16164 р. Наличие на складе: Поставка под заказ.
Описание: This book is a bench manual that provides in one volume all the important and unique technologies necessary to studies of mammary gland biology and breast
cancer. The chapters are written by experts in each area with an emphasis on nitty-gritty details that are key points for the successful use of a method. Sections include in vivo model
systems, special techniques for in vivo studies, in vitro model systems, and molecular analysis and gene transfer techniques.
Описание: This book explores and discusses some of the most important topics in post-genomics life and biopharmaceutical sciences such as pharmacogenomics, chemical genomics, chemical biology, structural genomics, drug discovery, biophysics and bioengineering with various chapters contributed by experts in respective fields.
Описание: Now in its seventh edition, Burger's Medicinal Chemistry, Drug Discovery and Development provides an established, recognized, authoritative and comprehensive source on medicinal chemistry and drug discovery and development. This flagship reference for
Автор: Brown, Dennis M. Название: Drug Delivery Systems In Cancer Therapy ISBN: 0896038882 ISBN-13(EAN): 9780896038882 Издательство: Springer Рейтинг: Цена: 24826 р. Наличие на складе: Поставка под заказ.
Описание: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.
Автор: Wang Название: Cancer Systems Biology ISBN: 1439811857 ISBN-13(EAN): 9781439811856 Издательство: Taylor&Francis Рейтинг: Цена: 24750 р. Наличие на складе: Поставка под заказ.
Описание: The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorgenesis, cancer research is enjoying a series of new discoveries and biological insights. Unique in its dualistic approach, this book introduces the concepts and theories of systems biology and their applications in cancer research. It presents basic cancer biology and cutting-edge topics of cancer research for computational biologists alongside systems biology analysis tools for experimental biologists.
Описание: Due to the rapid and steady growth of available low-cost computer power, the use of computers for discovering and designing new drugs is becoming a central topic in modern molecular biology and medicinal chemistry. In Computational Drug Discovery and Design: Methods and Protocols expert researchers in the field provide key techniques to investigate biomedical applications for drug developments based on computational chemistry. These include methods and techniques from binding sites prediction to the accurate inclusion of solvent and entropic effects, from high-throughput screening of large compound databases to the expanding area of protein-protein inhibition, toward quantitative free-energy approaches in ensemble-based drug design using distributed computing. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, reference to software and open source analysis tools, step-by-step, readily reproducible computational protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Computational Drug Discovery and Design: Methods and Protocols aids scientists in the continuing study of state-of-the-art concepts and computer-based methodologies.
Описание: An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and
Описание: Methods and advances for understanding phosphodiesterases (PDEs), a hot area of drug and therapeutic research Cyclic-nucleotide phosphodiesterases (PDEs) are critical for the regulation of processes from cell birth to cell death, but diseases of the ce
Автор: Cesario Название: Cancer Systems Biology, Bioinformatics and Medicine ISBN: 9400715668 ISBN-13(EAN): 9789400715660 Издательство: Springer Рейтинг: Цена: 19634 р. Наличие на складе: Поставка под заказ.
Описание: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.
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