Автор: Vivier Eric, Colonna Marco Название: Immunobiology of Natural Killer Cell Receptors ISBN: 3540260838 ISBN-13(EAN): 9783540260837 Издательство: Springer Рейтинг: Цена: 28609 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Natural Killer (NK) cells are large granular lymphocytes of the innate immune system. They are widespread throughout the body, being present in both lymphoid organs and non-lymphoid peripheral tissues. NK cells are involved in direct innate immune reactions against viruses, bacteria, parasites and other triggers of pathology, such as malignant transformation, all of which cause stress in affected cells. Importantly, NK cells also link the innate and adaptive immune responses, contributing to the initiation of adaptive immune responses and executing adaptive responses using the CD16 FcgRIIIA immunoglobulin Fc receptor. Such responses are mediated through two major effector functions, the direct cytolysis of target cells and the production of cytokines and chemokines. The authors focus here on the nature of recognition events by NK cells and address how these events are integrated to trigger these distinct and graded effector functions.
Автор: Matsumoto Rae R., Bowen Wayne D., Su Tsung-Ping Название: Sigma Receptors / Chemistry, Cell Biology and Clinical Implications ISBN: 0387365125 ISBN-13(EAN): 9780387365121 Издательство: Springer Рейтинг: Цена: 36583 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an update on sigma receptors, and summarizes recent advances in the medicinal chemistry, molecular biology, and cell biology of sigma receptors. It describes the functional effects mediated by these receptors and the potential clinical implications of these actions. This information is put in a historical perspective to help newcomers to the field successfully navigate the confusing early history surrounding these proteins, and provides a launching point from which future studies and research directions can easily be developed. Major advances in our understanding of sigma receptors have been made during the past few years. This book will facilitate exciting new research that could lead to significant advances in the treatment of neurologic, psychiatric, cardiovascular, immunologic, and gastrointestinal disorders through a better understanding of sigma receptors.
Автор: Peter Parham Название: The Immune System ISBN: 0815341466 ISBN-13(EAN): 9780815341468 Издательство: Taylor&Francis Рейтинг: Цена: 7236 р. Наличие на складе: Невозможна поставка.
Описание: "The Immune System, Third Edition" is designed for use in immunology courses for undergraduate, medical, dental, and pharmacy students. This class-tested
and proven textbook synthesizes the established facts of immunology into a comprehensible, coherent, and up-to-date account of how the human immune system works and the effects
it has on the health and survival of individuals and populations, making generous use of medical examples to illustrate points. The reader-friendly text, full-color illustrations, and section
and chapter summaries make the book accessible and easily understandable to students.
The Third Edition is a major revision and includes two new chapters: Innate
Immunity (Chapter 2) and Principles of Adaptive Immunity (Chapter 3). Former Chapter 12 has been divided into three chapters: vaccination (Chapter 14), transplantation (Chapter 15),
and cancer (Chapter 16). The number of end-of-chapter questions has been expanded and now include essay, multiple choice, and case study (USMLE-format) questions with answers
provided at the end of the book.
"The Immune System" is adapted from "Immunobiology" by Janeway, Travers, and Walport.
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