Pharmacogenomics an Introduction and Clinical Perspective, Bertino Joseph S

Автор: Yui-Wing Francis Lam
Название: Pharmacogenomics,
ISBN: 0123919185 ISBN-13(EAN): 9780123919182
Издательство: Elsevier Science
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Цена: 11620.00 р.
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Описание: Includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. This book contains review questions for an analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward.

Название: Pharmacogenomics
ISBN: 1588294404 ISBN-13(EAN): 9781588294401
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. The authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base. The methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and TaqMan assay for insertion/deletions.