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Making and Using Antibodies, Howard



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Автор: Howard
Название:  Making and Using Antibodies   (Говард: Изготовление и использование антител)
Издательство: Taylor&Francis
Классификация:
Иммунология
Биохимия
Промышленная химия

ISBN: 1439869081
ISBN-13(EAN): 9781439869086
ISBN: 1-439-86908-1
ISBN-13(EAN): 978-1-439-86908-6
Обложка/Формат: Paperback
Страницы: 458
Вес: 0.792 кг.
Дата издания: 10.09.2013
Серия: Medicine
Язык: ENG
Издание: 2 revised edition
Иллюстрации: 2 page/4 figure insert; 32 tables, black and white; 4 illustrations, color; 90 illustrations, black and white
Размер: 231 x 172 x 36
Читательская аудитория: Professional and scholarly
Ключевые слова: Biochemistry, MEDICAL / Biochemistry,MEDICAL / Immunology,MEDICAL / Pharmacology
Подзаголовок: A practical handbook, second edition
Ссылка на Издательство: Link
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Поставляется из: Англии
Описание: Antibodies protect us from a wide range of infectious diseases and cancers and have become an indispensable tool in science—both for conventional immune response research as well as other areas related to protein identification analysis. This second edition of Making and Using Antibodies: A Practical Handbook provides clear guidance on all aspects of how to make and use antibodies for research along with their commercial and industrial applications. Keeping pace with new developments in this area, all chapters in this new edition have been revised, updated, or expanded. Along with discussions of current applications, new material in the book includes chapters on western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present clear descriptions of basic methods for making and using antibodies and supply detailed descriptions of basic laboratory techniques. Each chapter begins with introductory material, allowing for a better understanding of each concept, and practical examples are included to help readers grasp the real-world scenarios in which antibodies play a part. From the eradication of smallpox to combating cancer, antibodies present an attractive solution to a range of biomedical problems. They are relatively easy to make and use, have great flexibility in applications, and are cost effective for most labs. This volume will assist biomedical researchers and students and pave the way for future discovery of new methods for making and using antibodies for a host of applications.
Дополнительное описание:




      Старое издание
Making and Using Antibodies

Автор: Gary C. Howard and Matthew R. Kaser
Название: Making and Using Antibodies
ISBN: 0849335280 ISBN-13(EAN): 9780849335280
Издательство: CRC Press
Цена: 11137 р.
Наличие на складе: Нет в наличии.
Описание: Written for professionals in the fields of biomedical research, this volume adopts a cookbook approach to presenting methods for the production, characterization, and use of antibodies. The book focuses on specific aspects of antibodies and takes readers on a step-by-step process from antigen preparation to immunizations, adjuvants, screening, purification, storage, and applications. Introductory material accompanies each chapter, giving readers a better understanding of the methods and applications. It covers basic techniques including enzyme-linked immunosorbent assay (ELISA), Western blotting, immunohistochemistry, and flow cytometry.


Biosimilars of Monoclonal Antibodies: A Practical Guide to Manufacturing, Preclinical, and Clinical Development

Автор: Liu
Название: Biosimilars of Monoclonal Antibodies: A Practical Guide to Manufacturing, Preclinical, and Clinical Development
ISBN: 1118662318 ISBN-13(EAN): 9781118662311
Издательство: Wiley
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Цена: 16093 р.
Наличие на складе: Поставка под заказ.

Описание: Addressing a significant need by describing the science and process involved to develop biosimilars of monoclonal antibody (mAb) drugs, this book covers all aspects of biosimilar development: preclinical, clinical, regulatory, manufacturing.

Название: Antibodies
ISBN: 148229110X ISBN-13(EAN): 9781482291100
Издательство: Taylor&Francis
Цена: 12645 р.
Наличие на складе: Поставка под заказ.

Immunochemical Techniques, Part F: Conventional Antibodies, Fc Re

Автор: Nathan P. Kaplan
Название: Immunochemical Techniques, Part F: Conventional Antibodies, Fc Re
ISBN: 0121819930 ISBN-13(EAN): 9780121819934
Издательство: Elsevier Science
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Цена: 5138 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Single Domain Antibodies

Автор: Saerens
Название: Single Domain Antibodies
ISBN: 161779967X ISBN-13(EAN): 9781617799679
Издательство: Springer
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Цена: 14492 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: The development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications.  In Single Domain Antibodies: Methods and Protocols, expert researchers examine single variable domain antibody fragments, referred to as VH, VL, VHH or VNAR. These fragments are the smallest intact antigen-binding fragments that can be produced recombinantly at low cost.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Kosma (Eds), Anticarbohydrate Antibodies

Название: Kosma (Eds), Anticarbohydrate Antibodies
ISBN: 3709108691 ISBN-13(EAN): 9783709108697
Издательство: Springer
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Цена: 19224 р.
Наличие на складе: Поставка под заказ.

Описание: Many pathogens and aberrant malignant cells express unique carbohydrates on their surface representing attractive targets for vaccine design. Considerable progress has recently been made in the identification of novel carbohydrate based vaccines and a large number has reached clinical phase studies. The success of several licensed carbohydrate based vaccines against bacterial pathogens such as Haemophilus influenzae type b, Neisseria meningitidis or Streptococcus pneumoniae demonstrates their great potential. However, the study of anti-carbohydrate antibodies is technically challenging and partly because of low affinities and promiscuous specificity they have not been medically exploited to full potential. The study of antibody specificities and identification of protective carbohydrate epitopes lies at the heart of successful vaccine design. In addition to therapy, antibodies in general serve as diagnostic tools in medical and scientific laboratories. In this setting high affinity and exquisite specificity are important factors for their successful use. “Anticarbohydrate Antibodies – from molecular basis to clinical application” compiles current knowledge on the immunological recognition of carbohydrates by the adaptive immune system from a molecular perspective providing fundamental insight needed for advancing clinically relevant diagnostics and therapeutic applications. Based on significant progress in the fields of glycoimmunology and structural biology in recent years, the book comprehensively reviews the state-of-the-art in defining the key elements of carbohydrate recognition by antibodies, the molecular mimicry of carbohydrate epitopes as well as the molecular features leading to specific and relaxed binding modes. Backed-up by a combination of modern technologies to elucidate structural details of carbohydrate-antibody interactions, biomedically important carbohydrate antigens from viral, bacterial, parasite, insect and tumor cells have been analyzed in in-depth reviews written by well-known experts in the field. Fundamental knowledge of these molecular mechanisms eventually provides a rational basis to improve efficacy of carbohydrate-based vaccines and to further refine diagnostic tools in detection of pathogens and malignant cells.

Monoclonal Antibodies in Biotechnology

Автор: Kenneth C. McCullough, Raymond E. Spier
Название: Monoclonal Antibodies in Biotechnology
ISBN: 0521103118 ISBN-13(EAN): 9780521103114
Издательство: Cambridge Academ
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Цена: 5725 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides a comprehensive description of principles, methodologies and applications of Monoclonal antibodies to modern science and industry.

Antibodies

Автор: Zanetti
Название: Antibodies
ISBN: 9057025892 ISBN-13(EAN): 9789057025891
Издательство: Taylor&Francis
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Цена: р.
Наличие на складе: Поставка под заказ.

Описание: Intended for specialists in B cell immunology, investigating such topics as movement of a monoclonal antibody from the laboratory into the clinic, the field of Fc receptors and the impact of monoclonal antibodies on diagnosis and treatment of human

Therapeutic Monoclonal Antibodies: From Bench to Clinic

Автор: Zhiquang
Название: Therapeutic Monoclonal Antibodies: From Bench to Clinic
ISBN: 0470117915 ISBN-13(EAN): 9780470117910
Издательство: Wiley
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Цена: 18497 р.
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Описание: * 70-chapter authoritative reference that covers therapeutic monoclonal antibody discovery, development, and clinical applications while incorporating principles, experimental data, and methodologies. * First book to address the discovery and development of antibody therapeutics in their entirety.

Antibodies to Endothelial Cells and Vascular Damage

Автор: Cervera
Название: Antibodies to Endothelial Cells and Vascular Damage
ISBN: 0849349141 ISBN-13(EAN): 9780849349140
Издательство: Taylor&Francis
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Цена: р.
Наличие на складе: Поставка под заказ.

Описание: Offers coverage of basic science and clinical implications of immunological interactions of antibodies to endothelial cells. This book is suitable for immunologists, rheumatologists, internists, and others interested in the subject.

Tumor Antigens Recognized by T-Cells and Antibodies.2003

Автор: Stauss
Название: Tumor Antigens Recognized by T-Cells and Antibodies.2003
ISBN: 0415296986 ISBN-13(EAN): 9780415296984
Издательство: Taylor&Francis
Рейтинг:
Цена: 14108 р.
Наличие на складе: Поставка под заказ.

Описание: Recent progress in fundamental tumor immunology has led to immunotherapy trials in patients with solid tumors and hematological malignancies. In the past, immunotherapy approaches were primarily based on enhancement of tumor immunity with cytokines and adjuvant therapy, without knowledge of relevant tumor antigens. The discovery of tumor antigens capable of eliciting immune responses has now resulted in the development of antigen-specific immunotherapy strategies. Vaccination with defined peptide epitopes, purified proteins, cell components, and whole cells expressing defined tumor antigens provides an opportunity to measure antigen-specific immune responses in vaccinated patients, and to correlate immunity with clinical outcome.Tumor Antigens Recognized by T Cells and Antibodies provides a comprehensive overview of the molecular nature of tumor antigens that can be recognized by antibodies, helper T lymphocytes and cytotoxic T lymphocytes. Novel strategies to enhance ineffective immunity against such antigens provide the basis for improved immunotherapy protocols for patient treatment. With contributions from a host of international experts in the field, this book provides invalua

Human Monoclonal Antibodies: Methods and Protocols

Автор: Michael Steinitz (Editor)
Название: Human Monoclonal Antibodies: Methods and Protocols
ISBN: 1627035850 ISBN-13(EAN): 9781627035859
Издательство: Springer
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Цена: 15894 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Therapeutic Antibodies

Автор: Antony S. Dimitrov (Ed.)
Название: Therapeutic Antibodies
ISBN: 1934115924 ISBN-13(EAN): 9781934115923
Издательство: Springer
Рейтинг:
Цена: 20569 р.
Наличие на складе: Поставка под заказ.

Описание: Presents a set of protocols for the discovery and development of therapeutic antibodies, featuring sections focusing on recombinant antigens, antibody libraries, antibody discovery, antibody engineering and antibody preclinical development. This work is suitable for those investigating and participating in this therapeutic market segment.


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