Автор: Preedy, Victor R. Название: Handbook of Cannabis and Related Pathologies ISBN: 0128007567 ISBN-13(EAN): 9780128007563 Издательство: Elsevier Science Рейтинг: Цена: 33013.00 р. Наличие на складе: Поставка под заказ.
Описание:
Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs.
Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug's effects from across scientific disciplines.
This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders.
Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects.
Автор: Fettweis Название: The Pathologies of Power ISBN: 1107041104 ISBN-13(EAN): 9781107041103 Издательство: Cambridge Academ Рейтинг: Цена: 12355.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The foreign policy of the United States is guided by deeply held beliefs, few of which are recognized much less subjected to rational analysis, Christopher J. Fettweis writes, in this, his third book. He identifies the foundations of those beliefs, explains how they have inspired poor strategic decisions in Washington and proceeds to discuss their origins.
Автор: Jana Название: Inflammation: the Common Link in Brain Pathologies ISBN: 9811017107 ISBN-13(EAN): 9789811017100 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This unifying theme of this book-with sections on mechanisms of defense and neuropathogenesis, neurological diseases, infections of the nervous system, neuropharmacology, and novel therapies-is interactions of the immune and nervous systems. It also discusses the role of inflammation as a key mediator of different brain disorders. There have been significant scientific advances in the multidisciplinary field of neuroimmunology / neuroinflammation in the past decade, and this book, edited under the guidance of Professor P. N. Tandon, fosters communication between those who share an interest in this exciting area, including neuroscientists, immunologists, cell biologists, clinicians and neuropharmacologists.
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis.
This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy.
Presents the most advanced information regarding the role of the autophagic system in life and death
Contains a direct focus on the role of a novel binuclear palladacycle complex that inhibits melanoma growth
Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation
States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities
Edited work with chapters authored by leaders in the field from around the globe--the broadest, most expert coverage available
Автор: Nair Название: Pathologies Of Paradise ISBN: 0813935172 ISBN-13(EAN): 9780813935171 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 10672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Pathologies of Paradise presents the rich complexity of anglophone Caribbean literature from pluralistic perspectives that contest the reduction of the region to Edenic or infernal stereotypes. But rather than reiterate the familiar critiques of these stereotypes, Supriya Nair draws on the trope of the detour to plumb the depths of anti-paradise discourse, showing how the Caribbean has survived its history of colonization and slavery. In her reading of authors such as Jamaica Kincaid, Michelle Cliff, V. S. Naipaul, Zadie Smith, Junot D az, and Pauline Melville, among others, she examines dominant symbols and events that shape the literature and history of postslavery and postcolonial societies: the garden and empire, individual and national trauma, murder and massacre, contagion and healing, grotesque humor and the carnivalesque. In ranging across multiple contexts, generations, and genres, the book maps a syncretic and flexible approach to Caribbean literature that demonstrates the supple literary cartographies of New World identities.
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. "Volume 8 Autophagy and Human Diseases," concentrates on the role of Autophagy in human diseases, including tumorigenesis. The diseases discussed include melanoma, liver cancer, pancreatic cancer, and neurodegenerative disorders. Loss of autophagy in the central nervous system causes neurodegeneration (Alzheimers disease, Huntington s disease, Parkin s disease, and Amyotrophic Lateral Sclerosis). Melanoma is one of the most serious diseases in humans. Autophagy plays a key role in the anticancer response to Chemotherapy. However, autophagy can increase or decrease the effectiveness of chemotherapy. The reasons for these contradictory effects are explained. Autophagy also plays a role in idiopathic inflammatory diseases, infection, and immunity. An explanation is given how autophagy is closely linked to control of innate and adaptive immune responses in host defense in part by regulating cytokine production. The role of autophagy in cutaneous malignant melanoma is discussed in detail and expression of Beclin 1 and LC3 autophagic genes in melanoma is included to explain the molecular mechanisms underlying this very serious disease, which tends to metastasize to the brain. The effect of the treatment of this disease using Terfenadine through the induction of autophagy and apoptosis is also included. Autophagy and apoptosis are two main mechanisms involved in programmed cell death.
Considering that autophagy is associated with numerous biological processes including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases, there is a great need to understanding its role. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological situations (conditions) mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood.
Volumes in the Series
Volume 1: Molecular Mechanisms. Elucidates autophagy s association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer s, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn s Disease, Gaucher Disease, Huntington s Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and exec
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