Автор: Prendergast Название: Cancer Immunotherapy. 2007 ISBN: 0123725518 ISBN-13(EAN): 9780123725516 Издательство: Elsevier Science Цена: 12815.00 р. Наличие на складе: Невозможна поставка. Описание: Highlights principles of immune suppression that drive cancer and offers ideas about how therapy can be improved by attacking these principles. This book demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models.
Автор: Yotnda Название: Immunotherapy of Cancer ISBN: 1607617854 ISBN-13(EAN): 9781607617853 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Автор: Ludewig Burkhard, Hoffmann Matthias W. Название: Adoptive Immunotherapy / Methods and Protocols ISBN: 1588294064 ISBN-13(EAN): 9781588294067 Издательство: Springer Рейтинг: Цена: 24456.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An authoritative collection of optimal techniques for producing and characterizing the immunologically active cells and effector molecules now gaining wide use in the clinical treatment of patients. Taking advantage of the latest technologies, the authors present readily reproducible experimental protocols for the study of dendritic cells, T cells, monoclonal antibodies, and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on the progress of selected approaches in clinical trials. Additional chapters cover the molecular definition of target antigens, mathematical modeling approaches to immunotherapy, and the utilization of regulatory T cells. The protocols make it possible to study the adoptive transfer of tailored antigen-specific immune cells and to improve the clinical application of adoptive immunotherapy.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Zhang Название: Progress in Cancer Immunotherapy ISBN: 9401775532 ISBN-13(EAN): 9789401775533 Издательство: Springer Рейтинг: Цена: 22203.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thisbook provides readers an extensive overview of recent progress in basicand clinical research on cancer immunotherapy. Thanks to rapid advances inmolecular biology and immunology, it has become increasingly evident thatcancer growth is influenced by host immune responses. With the success of anumber of clinical trials, immunotherapy has become a promising treatmentmodality of cancer. This book covers five major topics, including monoclonalantibodies, biological response modifiers, cancer vaccines, adoptive cellulartherapy and oncolytic viruses. It also examines the combination of differentimmune strategies as well as the combination of immunotherapy with othertreatments to increase anti-tumor effects. Throughthecomprehensive discussion of the topic, the book sheds valuable new light on thetreatment of tumors.
Автор: Lockey / Ledford Название: Allergens and Allergen Immunotherapy, Fourth Edition ISBN: 1420061976 ISBN-13(EAN): 9781420061970 Издательство: Informa Рейтинг: Цена: 20970.00 р. Наличие на складе: Нет в наличии.
Описание: Compiling the research of an influential team of investigators and scientists, Allergens and Allergen Immunotherapy is filled with quick reference charts, tables and indexes. Allergists, immunologists, and otolaryngologists will find this new streamlined fourth edition a great practical reference for on-the-go diagnosis, treatment, and management of allergies.
Автор: Sampson, John H. Название: Translational Immunotherapy of Brain Tumors ISBN: 0128024208 ISBN-13(EAN): 9780128024201 Издательство: Elsevier Science Рейтинг: Цена: 15917.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Besides the Privacy & Data Protection Foundation Courseware - English (ISBN: 9789401803595) publication you are advised to obtain the publication EU GDPR, A pocket guide (ISBN: 978 1 849 2855 5).Privacy & Data Protection Foundation covers the main subjects related to the protection of personal data. Candidates benefit from a certification that is designed to impart all the required knowledge to help ensure compliancy to the General Data Protection Regulation.Within the European Union regulations and standards regarding the protection of data are stringent. The General Data Protection Regulation (GDPR) went into force in May 2016 and organizations have until May 2018 to change their policies and processes to ensure they fully comply. Companies outside Europe will also need to comply when doing business in Europe. One of the solutions to comply in time is to qualify staff. Having certified professionals with the right level of knowledge can help prepare your organization to face these opportunities. The EXIN Privacy & Data Protection program covers the required knowledge of legislation and regulations relating to data protection and how this knowledge should be used to be compliant.
Автор: Rees Robert C. Название: Tumor Immunology and Immunotherapy ISBN: 0199676860 ISBN-13(EAN): 9780199676866 Издательство: Oxford Academ Рейтинг: Цена: 36036.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
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