Описание: Understand and apply the scientific advances that are revolutionizing cancer research and practice with Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely hailed as the definitive clinical reference in oncology – the second editon of this popular Primer focuses on the molecular biology information that is of critical importance to research scientists and clinical oncologists alike.Get up-to-date, dependable coverage of every important frontier in aspect of the molecular biology of cancer with contributions from a noteworthy roster of leading scientists and clinicians, featuring an updated version of the classic “Hallmarks of Cancer” by Hanahan and WeinbergSee how molecular biology advances are impacting clinical practice with separate chapters on each of the 19 most common cancer types.Navigate the challenges and ethical dilemmas of cancer genetics with a thorough section chapters on genetic counseling and genetic testing.Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to:Complete content with enhanced navigationA powerful search that pulls results from content in the book, your notes, and even the webCross-linked pages, references, and more for easy navigationHighlighting tool for easier reference of key content throughout the textAbility to take and share notes with friends and colleaguesQuick reference tabbing to save your favorite content for future use
Описание: Alan B. Weitberg, MD, and a panel of internationally recognized basic scientists and clinicians present a comprehensive discussion of lung cancer, including a practice-oriented review of its diagnosis, evaluation, and treatment. The contributors offer not only an understandable description of its molecular origins-an essential key to developing future therapies and preventive measures-but also rigorously discuss well-tested approaches, as well as those that are currently being evaluated for future use in both the laboratory and clinic. The book also elucidates the creation and effective deployment of treatment guidelines introduced by third party payers to improve clinical outcomes, even while lowering healthcare costs.
Описание: The book`s many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis.
Автор: William B. Coleman (Ed.) Название: The Molecular Basis of Human Cancer ISBN: 1934115185 ISBN-13(EAN): 9781934115183 Издательство: Springer Рейтинг: Цена: 18699 р. Наличие на складе: Поставка под заказ.
This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care.
The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.
Автор: Coleman Название: Molecular Basis of Human Cancer.2001 ISBN: 0896036340 ISBN-13(EAN): 9780896036345 Издательство: Wiley Рейтинг: Цена: 11215 р. Наличие на складе: Поставка под заказ.
Описание: Internationally renowned basic and clinical scientists provide an account of our best current understanding of the genetics of cancer. These authoritative contributors describe in detail each of the known molecular mechanisms governing neoplastic transformation in the breast, prostate, lung, liver, colon, and skin, and in the leukemias and lymphomas. Their discussion illuminates both recent developments and established concepts in epidemiology, molecular techniques, oncogenesis, and mutation mechanisms, as well as the chemical, viral, and physical mechanisms in cancer induction.
Описание: Principles of Molecular Diagnostics and Personalized Cancer Medicine" The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today’s subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention—all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discussions share insights from noted experts in cancer research, clinical trials, molecular diagnostics, personalized therapy, bioinformatics, and federal regulations. From the basic mechanisms of carcinogenesis to the most advanced molecular screening, staging, and treatment technologies, readers will discover clear and straightforward discussions directly relevant to patient diagnosis and care. Improve your understanding of… • The basic mechanisms of carcinogenesis— including material on cell proliferation, signal transduction pathways, cancer stem cells, and the interaction between genetics and environmental factors. • The most current molecular techniques —including polymerase chain reaction (PCR) technique, single nucleotide polymorphisms, cancer cytogenomics and epigenetics, whole-genome assessments, and next- generation sequencing. • Molecular tests —including molecular screening, minimal residual disease detection, circulating tumor cell tests, molecular tumor staging, and molecular cancer prognosis assessment. • Imaging and screening technologies —including molecular imaging, genetic tests, biostatistics, and bioinformatics. • The molecular basis of therapy —including critical molecules as special treatment targets, particularly genes/DNA, RNA, micro RNAs, proteins/antibodies, and nanoparticles. • Molecular diagnostics – including updated molecular diagnostic approaches to common malignancies and role of pathology in targeted cancer management. • Targeted treatment – including personalized medicine and targeted therapy for commonly occurring malignancies— plus insights on new approaches to targeted drug discovery and the future of molecular oncology!
Описание: Provides a comprehensive overview of cancer biology, covering the status of both research and treatment. This book covers topics extending from the molecular alterations found in cancer cells and their causes to the range of approaches to treatment. It is useful for both undergraduates and postgraduates.
Описание: Providing an in-depth summary of the molecular aspects of carcinogenesis, this text comprehensively covers chemical, radiation, and viral carcinogenesis - from animal and human test data to metabolism and DNA binding. It covers organic and metal carcinogenesis related to lung, breast, prostate, skin, liver, colon, brain, and thyroid cancers. The book explores the human implications of data regarding oncogenesis of transgenic and knockout mice and rats. It also covers the genomics and proteomics of chemoprevention, risk and exposure assessments, and regulation of carcinogens. Molecular Carcinogenesis and the Molecular Biology of Human Cancer is an ideal text for graduate courses in cancer.
Автор: Cooper Название: The Molecular Genetics of Lung Cancer ISBN: 354022985X ISBN-13(EAN): 9783540229858 Издательство: Springer Рейтинг: Цена: 15894 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Lung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk.The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.
Описание: Leading physician scientists and noted researchers review novel methods for determining the etiology of a variety of lung cancers and present readily reproducible techniques for examining the associated multitude of genetic abnormalities. The methods make it possible to detect these alterations at the cellular, DNA, and protein levels, to study the development of lung cancer in vitro and in vivo-either in situ or in the form of metastases, and to test targeted therapies with detailed model systems. An animal models section gives explicit instructions for setting up and testing these systems, which are rarely described in the literature.
Автор: Farid Nadir R. Название: Molecular Basis of Thyroid Cancer ISBN: 1402081065 ISBN-13(EAN): 9781402081064 Издательство: Springer Рейтинг: Цена: 23282 р. Наличие на складе: Поставка под заказ.
Описание: Thyroid cancer shows the fastest rate of increase in women in the USA. There is an urgent need to better understand its underlying causes, explore efficient and sensitive methods for its diagnosis, new methods of treatment and follow-up, based on the recent advances in technology.Molecular Basis of Thyroid Cancer brings together top-flight experts from across the globe to consider present state of the art treatment and techniques and what the future holds. The product of this effort is invaluable to endocrinologists, particularly those with an interest in the thyroid, molecular oncologists, nuclear medicine physicians and those in biotechnology intent on devising innovative therapies for cancer.
Автор: John Mendelsohn Название: The Molecular Basis of Cancer ISBN: 1416037039 ISBN-13(EAN): 9781416037033 Издательство: Elsevier Science Рейтинг: Цена: 16924 р. Наличие на складе: Невозможна поставка.
Описание: Successfully fighting cancer starts with understanding how it begins. This title explores the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. It explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions used in clinical trials.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru